2,350 research outputs found

    Analysis of the coupled effect of steel studs and surface emissivity on internal insulation systems performance

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    Many kinds of insulation systems have been developed and applied over the years to all the constructive elements of the building, but the two most used strategies remain the external and internal insulation of vertical walls. However, about the latter often a significant issue is neglected: the overestimation of the thermal performance by disregarding the contribution of construction elements. Usually a uniform stratigraphy of the wall is considered and the evaluation of the performance of a non-uniform one leads to erroneous results about the overall behavior of the system. In this paper, we developed a different approach considering the presence of the steel studs used to attach this package to the existing wall and their influence on the thermal behavior of the structure. Through both experimental and numerical analysis, the possible application of low-e sheets inside the air cavity in various configurations and with different thicknesses of insulation is also taken into account. Results showed that neglecting the presence of the steel studs leads to an erroneous evaluation of the conductance of the refurbished wall with errors reaching up to 28.0% in low-e high-insulated cases. This work highlights how careful the designers have to be when using standard formulas to compute the thermal resistance of internal insulation wall systems

    An analytical energy loss line shape for high depth resolution in ion beam analysis

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    The knowledge of the energy loss distribution in a single ion atom collision is a prerequisite for subnanometric resolution in depthprofiling techniques such as nuclear reaction profiling NRP and medium energy ion scattering MEIS . The usual Gaussian approximation specified by the stopping power and energy straggling is not valid for near surface regions of solids, where subnanometric or monolayer resolution can be achieved. In this work we propose an analytical formula for the line shape to replace the usual Gaussian distribution widely used in low resolution ion beam analysis. Furthermore, we provide a simple physical method to derive the corresponding shape parameters. We also present a comparison with full coupled channel calculations as well as with experimental data at nearly single collision condition

    Salivary cytokines as biomarkers for oral squamous cell carcinoma: A systematic review

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    The prognosis of patients with oral squamous carcinoma (OSCC) largely depends on the stage at diagnosis, the 5-year survival rate being approximately 30% for advanced tumors. Early diagnosis, including the detection of lesions at risk for malignant transformation, is crucial for limiting the need for extensive surgery and for improving disease-free survival. Saliva has gained popularity as a readily available source of biomarkers (including cytokines) useful for diagnosing specific oral and systemic conditions. Particularly, the close interaction between oral dysplastic/neoplastic cells and saliva makes such fluid an ideal candidate for the development of non-invasive and highly accurate diagnostic tests. The present review has been designed to answer the question: “Is there evidence to support the role of specific salivary cytokines in the diagnosis of OSCC?” We retrieved 27 observational studies satisfying the inclusion and exclusion criteria. Among the most frequent cytokines investigated as candidates for OSCC biomarkers, IL-6, IL-8, TNF-α are present at higher concentration in the saliva of OSCC patients than in healthy controls and may therefore serve as basis for the development of rapid tests for early diagnosis of oral cancer

    Kelvin-Helmholtz instability at proton scales with an exact kinetic equilibrium

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    The Kelvin-Helmholtz instability is a ubiquitous physical process in ordinary fluids and plasmas, frequently observed also in space environments. In this paper, kinetic effects at proton scales in the nonlinear and turbulent stage of the Kelvin-Helmholtz instability have been studied in magnetized collisionless plasmas by means of Hybrid Vlasov-Maxwell simulations. The main goal of this work is to point out the back reaction on particles triggered by the evolution of such instability, as energy reaches kinetic scales along the turbulent cascade. Interestingly, turbulence is inhibited when Kelvin-Helmholtz instability develops over an initial state which is not an exact equilibrium state. On the other hand, when an initial equilibrium condition is considered, energy can be efficiently transferred towards short scales, reaches the typical proton wavelengths and drives the dynamics of particles. As a consequence of the interaction of particles with the turbulent fluctuating fields, the proton velocity distribution deviates significantly from the local thermodynamic equilibrium, the degree of deviation increasing with the level of turbulence in the system and being located near regions of strong magnetic stresses. These numerical results support recent space observations from the Magnetospheric MultiScale mission of ion kinetic effects driven by the turbulent dynamics at the Earth's magnetosheath (Perri et al., 2020, JPlPh, 86, 905860108) and by the Kelvin-Helmholtz instability in the Earth's magnetosphere (Sorriso-Valvo et al., 2019, PhRvL, 122, 035102).Comment: 14 pages, 11 figure

    Antimicrobial effects of chemically functionalized and/or photo-heated nanoparticles

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    Antibiotic resistance refers to when microorganisms survive and grow in the presence of specific antibiotics, a phenomenon mainly related to the indiscriminate widespread use and abuse of antibiotics. In this framework, thanks to the design and fabrication of original functional nanomaterials, nanotechnology offers a powerful weapon against several diseases such as cancer and pathogenic illness. Smart nanomaterials, such as metallic nanoparticles and semiconductor nanocrystals, enable the realization of novel drug-free medical therapies for fighting against antibiotic-resistant bacteria. In the light of the latest developments, we highlight the outstanding capabilities of several nanotechnology-inspired approaches to kill antibiotic-resistant bacteria. Chemically functionalized silver and titanium dioxide nanoparticles have been employed for their intrinsic toxicity, which enables them to exhibit an antimicrobial activity while, in a different approach, photo-thermal properties of metallic nanoparticles have been theoretically studied and experimentally tested against several temperature sensitive (mesophilic) bacteria. We also show that it is possible to combine a highly localized targeting with a plasmonic-based heating therapy by properly functionalizing nanoparticle surfaces with covalently linked antibodies. As a perspective, the utilization of properly engineered and chemically functionalized nanomaterials opens a new roads for realizing antibiotic free treatments against pathogens and related diseases
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