683 research outputs found

    Rethinking digital copyright law for a culturally diverse, accessible, creative Europe. - D3.3:Survey Data Perspectives Authors and Performers

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    These two reports represent the work done as part of the reCreating Europe project on Authors and Performers and their experience with digital and disruptive factors and how they impact them professionally and financially. The first deliverable (D3.2) represents the survey questionnaire developed by Abeer Pervaiz and Joost Poort and the ensuing data set

    From invention to industry from a social movement perspective: the emergence of the 3D printing industry

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    In the entrepreneurship literature, the phenomenon of industry emergence has been largely investigated from an institutional perspective. Appropriate institutions would allow then a group of individual entrepreneurs (\u201cthe heroes\u201d) to create an industry through innovative ventures. New ventures create new industries and firm entry, survival, and exit drive industry evolution. Our research, however, explores what creates the favorable set of circumstances for new ventures to emerge and focuses on the pre-emergence phase and we propose that the patterns of emergence resemble those of social movements. Through an actor perspective, this research highlights the existence of diverse actors, not necessarily entrepreneurs, who are necessary to trigger a collective action during the pre-emergence phase of industries. This research is also distinct from entrepreneurial ecosystems as its development already requires some successful entrepreneurial action. The 3D printing industry was chosen as a single longitudinal case study, where the actors are the embedded units of analysis. The findings of the study lead to the identification of three aggregate dimensions\u2014\u201cSocial Movement Composition,\u201d Temporal Engagement,\u201d and \u201cCoalitions Development\u201d\u2014that were prevalent during the pre-emergence phase of the 3D printing industry. Our propositions emphasize the importance of large collective action and the role of multiple actors in order to create the conditions for, first, firm emergence and, the second, to the process of industry emergence

    Murine Typhus Presenting with Acute Psychosis and Disseminated Intravascular Coagulation: A Case Report

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    Murine typhus is an endemic infectious disease caused by Rickettsia typhi and is transmitted by fleas. It typically causes a mild illness with symptoms of fever, rash, headache, chills, and non-specific gastrointestinal complaints. However, there have been no reported cases in the literature of murine typhus infection causing symptoms of acute psychosis and disseminated intravascular coagulation (DIC). A 30-year-old female with a history of gastric bypass and chronic pain syndrome presented to the emergency department with altered mental state and fever. She developed vivid visual hallucinations, DIC, and hypoxia with pulmonary opacities, ultimately requiring intubation. Magnetic resonance imaging (MRI) showed leptomeningeal enhancement with unremarkable cerebrospinal fluid (CSF) studies. Serum murine typhus serology came back positive. Doxycycline therapy was initiated, which resulted in complete patient recovery. This case shows that murine typhus infection may present with acute psychosis and can mimic DIC, leading to diagnostic confusion. MRI sequences may show leptomeningeal enhancement, which has never been reported before in patients with typhus. Early neurological imaging using advanced MRI sequences for patients presenting with altered sensorium, visual hallucinations, and symptoms similar to thrombotic thrombocytopenic purpura (TTP) may help with early diagnosis, decreased hospital stay, and better prognosis

    A Rare Presentation of Cardiac Aspergilloma in an Immunocompetent Host: Case Report and Literature Review

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    Cardiac aspergilloma is exceptionally rare with only a handful of cases reported and majority of them being in immunocompromised patients. Here, we present a case of cardiac aspergilloma involving the right and left ventricle in an immunocompetent patient that initially presented with acute limb ischemia. He was later found to have a cardiac mass with histopathological diagnosis confirming Aspergillus species. Despite aggressive medical and surgical interventions, the patient had an unfavorable outcome due to low suspicion of invasive fungal endocarditis given his immunocompetent status. Cardiac aspergilloma should remain in the differential diagnosis of immunocompetent patients as early clinical suspicion will result in early treatment and decreased mortality. Novel therapies are required to decrease mortality in the future from this fatal disease

    Single stage bilateral total hip replacement: Is it an option or a risk?

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    Abstract OBJECTIVE: To evaluate safety and feasibility of two-stage total hip arthroplasty and to compare it with single-stage procedure. METHODS: The retrospective study was conducted at The Aga Khan University Hospital and comprised all cases of total hip replacements between January 2001 and December 2014 that were retrieved from the database using International Classification of Diseases (9th Revision) coding. A standardised questionnaire was completed, including patient demographics, primary diagnosis, peri and postoperative morbidity and mortality. Differences among patients\\u27 data were analysed using chi square test for dichotomous variables and student t-test for continuous variables. RESULTS: Of the 48 cases, 34(71%) had single-stage bilateral total hip replacement and 14(29%) had two-stage procedure. The mean hospital stay in the single-stage group was 8.1±3.2 days compared to 19.6±5 days in the other group. The two-stage group required a significantly greater need for transfusion compared to the single-stage group (P\u3c0.05). There was no statistically significant increase in peri or postoperative complication (p\u3e 0.05). CONCLUSIONS: Simultaneous bilateral total hip arthroplasty was found to be a safe and viable option with a decreased transfusion requirement and shorter hospital stay along with no significant increase in morbidity or mortality

    Experimental study of masonry wall exposed to blast loading

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    The challenge of protecting the nation against the attack of terrorism has raised the importance to explore the understanding of building materials against the explosion. Unlike most of the building materials, brick masonry materials offer relatively small resistance against blast loading. In this research, a brick masonry wall was exposed to varying blast load at different scaled distances. Six tests with different amounts of explosives at various distances were carried out. Pressure time history, acceleration time history and strain at specific location were measured. The parameters measured from experimental pressure time history and acceleration time history is compared with those determined by ConWep to establish the correlations between experimental determined records and ConWep values. The experimental results were also compared with some researchers. These correlations may assist in understanding the behaviour of masonry structures subjected to explosive loading
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