A giant solid cystic inferior fourth ventricle subependymoma: Case report and literature review

Subependymomas are a rare subtype of ependymomas, slow growing WHO grade I tumors that develop either intracranial from the subependymal glial precursor cells layer of the ventricles or intramedullary. These tumors originate in the undifferentiated Subependymal layer of cells that can become either ependymocytes or astrocytes. Most of the subependymomas are located inside the fourth ventricle (50-60%). We reviewed the case of a 40 years old woman with a giant solid cystic fourth ventricle ependymoma. The patient underwent total resection of the tumor through a subociipital transvermian approach. We discussed the characteristics of these benign tumors and reviewed the literature on this subject and concluded that total resection is the treatment of choice for symptomatic Subependymomas localized in posterior fossa

Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post‐hoc analysis of a randomised controlled trial

Magnesium status and vitamin B6 intake have been linked to mental health and/or quality of life (QoL). In an 8‐week Phase IV randomised controlled study in individuals with low magnesemia and severe/extremely severe stress but who were otherwise healthy, greater stress reduction was achieved with magnesium combined with vitamin B6 than with magnesium alone. We present a previously unreported secondary analysis of the effect of magnesium, with and without vitamin B6, on depression, anxiety, and QoL. Adults with Depression Anxiety Stress Scales (DASS‐42) stress subscale score >18 were randomised 1:1 to magnesium + vitamin B6 combination (Magne B6®; daily dose 300 and 30 mg, respectively) or magnesium alone (Magnespasmyl®; daily dose 300 mg). Outcomes included changes from baseline in DASS‐42 depression and anxiety scores, and QoL (Short Form‐36 Health Survey). DASS‐42 anxiety and depression scores significantly improved from baseline to week 8 with both treatments, particularly during the first 4 weeks. Improvement in QoL continued over 8 weeks. Participants' perceived capacity for physical activity in daily life showed greater improvement with magnesium + vitamin B6 than magnesium alone (Week 4). In conclusion, magnesium supplementation, with or without vitamin B6, could provide a meaningful clinical benefit in daily life for individuals with stress and low magnesemia

Impact of Aligning Climatological Day on Gridding Daily Maximum-Minimum Temperature and Precipitation over Canada

On 1 July 1961, the climatological day was redefined to end at 0600 UTC at all principal climate stations in Canada. Prior to that, the climatological day at principal stations ended at 1200 UTC for maximum temperature and precipitation and 0000 UTC for minimum temperature and was similar to the climatological day at ordinary stations. Hutchinson et al. reported occasional larger-than-expected residuals at 50 withheld stations when the Australian National University Spline (ANUSPLIN) interpolation scheme was applied to daily data for 1961-2003, and it was suggested that these larger residuals were in part due to the existence of different climatological days. In this study, daily minimum and maximum temperatures at principal stations were estimated using hourly temperatures for the same climatological day as local ordinary climate stations for the period 1953-2007. Daily precipitation was estimated at principal stations using synoptic precipitation data for the climatological day ending at 1200 UTC, which, for much of the country, was close to the time of the morning observation at ordinary climate stations. At withheld principal stations, the climatological-day adjustments led to the virtual elimination of large residuals in maximum and minimum temperature and a marked reduction in precipitation residuals. Across all 50 withheld stations the climatological day adjustments led to significant reductions, by around 12% for daily maximum temperature, 15% for daily minimum temperature, and 22% for precipitation, in the residuals reported by Hutchinson et al

The problem of sexual inversion in the minnow, Phoxinus phoxinus (L.)

none3The incidence of sexual inversion in Phoxinus phoxinus has been studied by examining histologically (a) the gonads of 406 adult specimens caught from the wild during a period of 16 months, (b) the gonads of 168 adults kept in captivity in groups with an experimentally altered sex-ratio, and (c) the differentiation of the gonads in the fry. All the adults had either testes or ovaries and no case of intersexuality was observed. For both testis and ovary, we recognized two phases, depending on the seasonal cycle: an active spring-summer phase, corresponding with the period of reproduction, and a quiescent autumn-winter phase. The ovaries showed an asynchrony in oocyte development, which is typical of species that spawn many times during the breeding season. In P. phoxinus the ovaries are easily recognizable just one month after hatching and testes are well differentiated in 2-month-old fingerlings. Differentiation is, therefore, precocious and follows a pattern typical of gonochoristic species in which hermaphroditism never occurs.noneM. B. Rasotto;P. Cardellini;E. MarconatoRasotto, MARIA BERICA; P., Cardellini; E., Marconat