Enhancement and suppression effects resulting from information structuring in sentences

Information structuring through the use of cleft sentences increases the processing efficiency of references to elements within the scope of focus. Furthermore, there is evidence that putting certain types of emphasis on individual words not only enhances their subsequent processing, but also protects these words from becoming suppressed in the wake of subsequent information, suggesting mechanisms of enhancement and suppression. In Experiment 1, we showed that clefted constructions facilitate the integration of subsequent sentences that make reference to elements within the scope of focus, and that they decrease the efficiency with reference to elements outside of the scope of focus. In Experiment 2, using an auditory text-change-detection paradigm, we showed that focus has similar effects on the strength of memory representations. These results add to the evidence for enhancement and suppression as mechanisms of sentence processing and clarify that the effects occur within sentences having a marked focus structure

Expanding the use of real-time electromagnetic tracking in radiation oncology.

In the past 10 years, techniques to improve radiotherapy delivery, such as intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT) for both inter- and intrafraction tumor localization, and hypofractionated delivery techniques such as stereotactic body radiation therapy (SBRT), have evolved tremendously. This review article focuses on only one part of that evolution, electromagnetic tracking in radiation therapy. Electromagnetic tracking is still a growing technology in radiation oncology and, as such, the clinical applications are limited, the expense is high, and the reimbursement is insufficient to cover these costs. At the same time, current experience with electromagnetic tracking applied to various clinical tumor sites indicates that the potential benefits of electromagnetic tracking could be significant for patients receiving radiation therapy. Daily use of these tracking systems is minimally invasive and delivers no additional ionizing radiation to the patient, and these systems can provide explicit tumor motion data. Although there are a number of technical and fiscal issues that need to be addressed, electromagnetic tracking systems are expected to play a continued role in improving the precision of radiation delivery

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs

Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected animals or consumption of contaminated animal meats. Genotypes 3 and 4 HEV are zoonotic and infect humans and other animal species, whereas genotypes 1 and 2 HEV are restricted to humans. There exists a single serotype of HEV, although the cross-protective ability among the animal HEV strains is unknown. Thus, in this study we expressed and characterized N-terminal truncated ORF2 capsid antigens derived from swine, rat, and avian HEV strains and evaluated their cross-protective ability in a pig challenge model. Thirty, specific-pathogen-free, pigs were divided into 5 groups of 6 pigs each, and each group of pigs were vaccinated with 200 µg of swine HEV, rat HEV, or avian HEV ORF2 antigen or PBS buffer (2 groups) as positive and negative control groups. After a booster dose immunization at 2 weeks post-vaccination, the vaccinated animals all seroconverted to IgG anti-HEV. At 4 weeks post-vaccination, the animals were intravenously challenged with a genotype 3 mammalian HEV, and necropsied at 4 weeks post-challenge. Viremia, fecal virus shedding, and liver histological lesions were compared to assess the protective and cross-protective abilities of these antigens against HEV challenge in pigs. The results indicated that pigs vaccinated with truncated recombinant capsid antigens derived from three animal strains of HEV induced a strong IgG anti-HEV response in vaccinated pigs, but these antigens confer only partial cross-protection against a genotype 3 mammalian HEV. The results have important implications for the efficacy of current vaccines and for future vaccine development, especially against the novel zoonotic animal strains of HEV

The 2.5-5.0 micron spectra of Io: Evidence for H2S and H2O frozen in SO2

The techniques of low temperature spectroscopy are applied to identify the constituents of the ices covering the surface of Io, a satellite of Jupiter. Infrared spectra of Io in the 4000-2000 cm exp -1 region, including new observational data, are analyzed using laboratory studies of plausible surface ices

Near Infrared Spectra of H2O/HCN Mixtures

Cassini's VIMS has already returned exciting results interpreting spectra of Saturn's icy satellites. The discovery of unidentified features possibly due to CN compounds inspired the work reported here. We wanted to test HCN as a possibility for explaining these features, and also explore how the features of HCN change when mixed with H2O. We have previously noted that mixing H20 and CO2 produces new spectral features and that those features change with temperature and mixing ratio

A computational approach to implicit entities and events in text and discourse

In this paper we will focus on the notion of “implicit” or lexically unexpressed linguistic elements that are nonetheless necessary for a complete semantic interpretation of a text. We refer to “entities” and “events” because the recovery of the implicit material may affect all the modules of a system for semantic processing, from the grammatically guided components to the inferential and reasoning ones. Reference to the system GETARUNS offers one possible implementation of the algorithms and procedures needed to cope with the problem and enables us to deal with all the spectrum of phenomena. The paper will address at first the following three types of “implicit” entities and events: – the grammatical ones, as suggested by a linguistic theories like LFG or similar generative theories; – the semantic ones suggested in the FrameNet project, i.e. CNI, DNI, INI; – the pragmatic ones: here we will present a theory and an implementation for the recovery of implicit entities and events of (non-) standard implicatures. In particular we will show how the use of commonsense knowledge may fruitfully contribute to find relevant implied meanings. Last Implicit Entity only touched on, though for lack of space, is the Subject of Point of View, which is computed by Semantic Informational Structure and contributes the intended entity from whose point of view a given subjective statement is expressed

Orbital dynamics of Cygnus X-3

Orbital-phased-resolved infrared spectra of Cygnus X-3 in outburst and quiescence, including tomographic analysis, are presented. We confirm the phasing of broad HeII and NV lines in quiescence, such that maximum blue shift corresponds to the X-ray minimum at phase = 0.00 +/- 0.04. In outburst, double-peaked HeI structures show a similar phasing with two significant differences: (a) although varying in relative strength, there is continuous line emission in blue and red peaks around the orbit, and (b) an absorption component, ~1/4 of an orbit out of phase with the emission features, is discerned. Doppler tomograms of the double-peaked profiles are consistent with a disk-wind geometry, rotating at velocities of 1000 km/s. Regrettably, the tomography algorithm will produce a similar ring structure from alternative line sources if contaminated by overlying P Cygni profiles. This is certainly the case in the strong 2.0587 micron HeI line, leading to an ambiguous solution for the nature of double-peaked emission. The absorption feature, detected 1/4 of an orbit out of phase with the emission features, is consistent with an origin in the He star wind and yields for the first time a plausible radial velocity curve for the system. We directly derive the mass function of the system, 0.027 M_sun. If we assume a neutron star accretor and adopt a high orbital inclination, i > 60 degrees, we obtain a mass range for the He star of 5 M_sun < M_WR < 11 M_sun. Alternatively if the compact object is a black hole, we estimate M_BH < 10 M_sun. We discuss the implications of these masses for the nature and size of the binary system.Comment: Accepted for publication in ApJ main journa