Novel Zn (II) complexes of N1,N2-bis(2-nitrobenzylidene) ethane-1,2-diamine as effective corrosion inhibitors for mild steel in 5.0 M HCl solution

Mild steel is a common material and has found widespread use in many industries. However, its ability to corrode in aggressive environments limits its application. This study aims to study mild steel corrosion inhibition in 5.0 M HCl using Zn (II) complexes (C3), based on N1,N2-bis(2-nitrobenzylidene)ethane-1,2-diamine (L2). Measurements of electrochemical techniques, such as polarization plots and Electrochemical Impedance Spectroscopy (EIS) were used to study their behavior. Polarization plots revealed that these inhibitors are mixed type. The inhibition efficiency increases with increasing inhibitors concentrations. The impedance diagrams show that the charge transfer resistance increase in the presence of inhibitors and the value of double layer capacity decrease. The inhibition efficiency reaches 90% for 5.10-4M of C3. This result in good agreement that inhibitors studied act by forming an inhibitor film on steel surface. The surface of the steel before and after corrosion was characterized by the Scanning Electron Microscope coupled with Dispersive Energy Analysis (SEM-EDAX), The results of electrochemical studie and the surface analysis of the steel show that these the complexe is effective for the protection of steel in 5.0 M HCl, in addition, this complexe is adsorbed to the steel surface following the isotherm of Langmuir

Tuberculosis of the parotid gland: Histology surprise

The Parotid gland is rarely involved in tuberculosis, even in endemic countries. We report a case of a 26 year-old woman with no medical history, who presented with a swelling of the parotid lodge. Pathology performed after surgery found a tuberculous parotitis, and the patient received  anti-tuberculous regimen with a satisfactory evolution. We discuss both diagnostic and therapeutic modalities for this infection

Impact of peanut shells, olive pomace, and plaster on the dielectric properties of PA6

Polyamide 6 (PA6) is among the most widely used technical polymers due to its excellent balance between performance and cost. The diversity of its applications reflects its main qualities (good mechanical properties, thermal stability, resistance to many solvents and bases, etc.). PA6 is often used as an electrical insulator, and in this study, we have shown that we can keep this property by using Plaster (PL) as reinforcement, just as we can by incorporating bio-reinforcements including peanut shell powder (PSP) or olive pomace powder (OPP) to modify this behavior. This was achieved by studying the electrical and dielectric properties of PA6 and PA6/PSP, PA6/OPP, and PA6/PL composites using impedance spectroscopy in the glass transition region ranging from 20°C to 50°C in a range frequency 1Hz - 1MHz. The results show that the PA6/PSP and PA6/OPP composites exhibited low resistance; therefore, very good electrical conductivity was recorded. However, PA6/PL inherits almost the same characteristics as PA6. The present study asserts that the presence of charges in the composite's interfacial region greatly influences the electrical and dielectric behavior and that this behavior is strongly affected near the Tg

Synthesis, Characterization, DFT Mechanistic Study, Antimicrobial Activity, Molecular Modeling, and ADMET Properties of Novel Pyrazole-isoxazoline Hybrids

A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was successfully synthesized, characterized, and evaluated for their antimicrobial responses. The synthesized compounds were obtained utilizing N-alkylation and 1,3-dipolar cycloaddition reactions, as well as their structures were established through spectroscopic methods and confirmed by mass spectrometry. To get more light on the regioselective synthesis of new hybrid compounds, mechanistic studies were performed using DFT calculations with B3LYP/6-31G(d,p) basis set. Additionally, the results of the preliminary screening indicate that some of the examined hybrids showed potent antimicrobial activity, compared to standard drugs. The results confirm that the antimicrobial activity is strongly dependent on the nature of the substituents linked pyrazole and isoxazoline rings. Furthermore, molecular docking studies were conducted to highlight the interaction modes between the investigated hybrid compounds and the Escherichia coli and Candida albicans receptors. Notably, the results demonstrate that the investigated compounds have strong protein binding affinities. The stability of the formed complexes by the binding between the hybrid compound 6c, and the target proteins was also confirmed using a 100 ns molecular dynamics simulation. Finally, the prediction of ADMET properties suggests that almost all hybrid compounds possess good pharmacokinetic profiles and no signs of observed toxicity, except for compounds 6e, 6f, and 6g