Quantum-secured blockchain

Blockchain is a distributed database which is cryptographically protected against malicious modifications. While promising for a wide range of applications, current blockchain platforms rely on digital signatures, which are vulnerable to attacks by means of quantum computers. The same, albeit to a lesser extent, applies to cryptographic hash functions that are used in preparing new blocks, so parties with access to quantum computation would have unfair advantage in procuring mining rewards. Here we propose a possible solution to the quantum era blockchain challenge and report an experimental realization of a quantum-safe blockchain platform that utilizes quantum key distribution across an urban fiber network for information-theoretically secure authentication. These results address important questions about realizability and scalability of quantum-safe blockchains for commercial and governmental applications.Comment: 7 pages, 2 figures; published versio

Vulnerability of primitive human placental trophoblast to Zika virus

Infection of pregnant women by Asian lineage strains of Zika virus (ZIKV) has been linked to brain abnormalities in their infants, yet it is uncertain when during pregnancy the human conceptus is most vulnerable to the virus. We have examined two models to study susceptibility of human placental trophoblast to ZIKV: cytotrophoblast and syncytiotrophoblast derived from placental villi at term and colonies of trophoblast differentiated from embryonic stem cells (ESC). The latter appear to be analogous to the primitive placenta formed during implantation. The cells from term placentas, which resist infection, do not express genes encoding most attachment factors implicated in ZIKV entry but do express many genes associated with antiviral defense. By contrast, the ESC-derived trophoblasts possess a wide range of attachment factors for ZIKV entry and lack components of a robust antiviral response system. These cells, particularly areas of syncytiotrophoblast within the colonies, quickly become infected, produce infectious virus and undergo lysis within 48 h after exposure to low titers (multiplicity of infection > 0.07) of an African lineage strain (MR766 Uganda: ZIKVU) considered to be benign with regards to effects on fetal development. Unexpectedly, lytic effects required significantly higher titers of the presumed more virulent FSS13025 Cambodia (ZIKVC). Our data suggest that the developing fetus might be most vulnerable to ZIKV early in the first trimester before a protective zone of mature villous trophoblast has been established. Additionally, MR766 is highly trophic toward primitive trophoblast, which may put the early conceptus of an infected mother at high risk for destruction

Modelling of electromechanical processes of electric drive on the example of one of the coordinates (the rotation mechanism) of an industrial robot-manipulator TOUR-10

The article describes the stages of development and preparation of mathematical models of kinematics and actuator control for robot manipulator TOUR-10. The mathematical model includes 3 stages of modeling. The first step is to create a mathematical model of electric drive control system of the robot manipulator and the analysis of obtained transients of the stator current, speed and position of the motor shaft. The second step is to create a mathematical model of the mechanical system of the robot manipulator. The third stage is the creation of complex Electromechanical systems of a robot manipulator.В статье описываются этапы разработки и подготовки математической модели одной из координат (механизма поворота) кинематики и системы управления электропривода для многозвенного робота манипулятора ТУР-10. Математическая модель включает в себя 3 части моделирования. Первая часть – это создание математической модели системы управления электроприводом робота манипулятора и анализ полученных переходных процессов тока статора, скорости и положения вала двигателя. Вторая часть – это создание математической модели механической системы робота манипулятора. Третья часть – это создание комплексной электромеханической системы робота манипулятора

State and prospects using hardware-software simulator electrical complex in educational process

The problems of the use of real-time simulation in the educational process in the study of subjects related to the development of electric systemsРассматриваются вопросы использования симуляторов реального времени в учебном процессе при изучении дисциплин, связанных с освоением систем электроприводо

Research of a bi-directional DC-DC converter integrated in electric car power installation

This article presents the results of the simulation study of the bi-directional DC converter, including the time diagrams of the electric vehicle speed, voltage and current changes in various experiments, Also presented are the results of efficiency change and charge level, when using a bi-directional converter as well as without using it. The HFEDC (Highway Fuel Economy Driving Schedule) model was chosen for the simulation of the electric vehicle drive model using units simulating standardized driving cycles and as an algorithm for changing the vehicle's control signal. Studies of the operating modes of the electrical equipment and the electric vehicle with the DC voltage conversion device in the power circuit of the DC source have been carried out by computer simulation in specialized programs for the study of dynamic systems. The simulation model of the reversible DC converter in the electrical power equipment of an electric vehicle was constructed on the basis of mathematical models of the individual elements reflecting their real physical properties. The present solution is the use of two-way DC voltage converters in the power conversion systems of modern electric drives, including the electric propulsion systems of prospective vehicles improves the efficiency of these systems. © Published under licence by IOP Publishing Ltd

Project distance learning for students with intellectual disabilities

In order to include all students, despite the disability, in a general education class, general education teachers should have the skills to work with them. Many students with mental retardation can be educated in an inclusive environment if they are provided with appropriate support, for example through training methods such as teaching, project-based, which actively involves students in studying real problems and answering the relevant questions. This article focuses on the use of distance learning based on projects for teaching children with intellectual deficiency in inclusive educationС целью включения всех обучающихся, несмотря на инвалидность, в общеобразовательный класс, педагоги общего образования должны иметь навыки работы с ними. Многие учащиеся с умственной отсталостью могут обучаться в инклюзивной среде, если им обеспечена надлежащая поддержка, например, посредством учебных методов, таких как обучение на основе проектов, которое активно привлекает учащихся к изучению реальных проблем и ответов на соответствующие вопросы. В этой статье основное внимание уделяется использованию метода дистанционного обучения на основе проектов для обучения детей с интеллектуальной недостаточностью в рамках инклюзивного образовани

Антиаритмические свойства монохлоргидрата N-дезацетиллаппаконитина

The aim of the investigation was the research of the N-deacetyllappaconitine hydrochloride antiarrhythmic properties. It was found that the studied substance was effective on the cardiac arrhythmias model caused by aconitine hydrochloride, but does not act on the models of calciume chlorideinduced arrhythmias and reperfusion ventricular fibrillation. The studied compound is less toxic than the comparison drug lappaconitine hydrobromide and acts in lower doses on the aconitine model of arrhythmias. N-Deacetyllappaconitine hydrochloride appears to be a Class I antiarrhythmic agent according to the Vaughan Williams classification.Цель исследования – изучить антиаритмические свойства монохлоргидрата N-дезацетиллаппаконитина. Установлено, что изучаемое вещество эффективно на модели нарушений ритма сердца, вызываемых аконитина гидрохлоридом, но не действует на моделях хлоридкальцевых и реперфузионных фибрилляций желудочков сердца. Изучаемое соединение менее токсично, чем препарат сравнения лаппаконитина гидробромид, и действует в меньших дозах на аконитиновой модели аритмий. Монохлоргидрат N-дезацетиллаппаконитина, по-видимому, является антиаритмическим средством I класса по классификации Vaughan Williams