52 research outputs found
Graphene-based ultrathin flat lenses
Flat lenses when compared to curved surface lenses have the advantages of being aberration free and they offer a compact design necessary for a myriad of electro-optical applications. In this paper we present flat and ultra-thin lenses based on graphene, the world’s thinnest known material. Monolayers and low number multilayers of graphene were fabricated into Fresnel zones to produce Fresnel zone plates which utilize the reflection and transmission properties of graphene for their operation. The working of the lens and their performance in the visible and terahertz regimes was analyzed computationally. Experimental measurements were also performed to characterize the lens in the visible regime and a good agreement was obtained with the simulations. The work demonstrates the principle of atom thick graphene-based lenses, with perspectives for ultra-compact integration.HB would like to thank The Leverhulme Trust for the research funding. QD is supported by Bureau of International Cooperation, Chinese Academy of Sciences (121D11KYSB20130013).This is the accepted manuscript. The final version is available from ACS at http://pubs.acs.org/doi/abs/10.1021/ph500197j
Non-technical skills evaluation in the critical care air ambulance environment: introduction of an adapted rating instrument - an observational study
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer
We attempted to investigate immunohistochemical expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor (PD-ECGF), c-erbB-2, matrix metalloproteinase-2 (MMP-2), and MMP-9 using surgical specimens of 119 non-small-cell lung carcinoma (NSCLC) cases and to evaluate the relationship between the expression levels of each molecule and clinicopathological factors or prognosis. VEGF expression levels were significantly associated with the local invasion (P = 0.0001), lymph node involvement (pN-factor) (P = 0.0019), pathological stage (p-stage) (P = 0.0027) and lymphatic permeation (P = 0.0389). PD-ECGF expression levels were associated with pN-factor (P = 0.0347). MMP-2 expression levels were associated with pN-factor (P = 0.004) and lymphatic permeation (P = 0.0056). Also, MMP-9 expression levels showed a significant correlation to local invasion (P = 0.0012), pN-factor (P = 0.0093) and p-stage (P = 0.0142). Multivariate analysis showed VEGF to be the most related to local invasion (P = 0.0084), and MMP-2 was the only factor with significant independent impact on lymphatic permeation (P = 0.0228). Furthermore, log-rank analysis showed significant association with poor survival by VEGF, bFGF, MMP-2 and MMP-9. Especially, combined overexpression of VEGF and MMP-2 revealed poor prognosis, our study might provide a basis for the better evaluation of biological characteristics and a new therapeutic strategy based on chemotherapy. © 2001 Cancer Research Campaign http://www.bjcancer.co
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
Meeting abstrac
Non-technical Skills in Healthcare
AbstractNon-technical Skills (NTS) are a set of generic cognitive and social skills, exhibited by individuals and teams, that support technical skills when performing complex tasks. Typical NTS training topics include performance shaping factors, planning and preparation for complex tasks, situation awareness, perception of risk, decision-making, communication, teamwork and leadership. This chapter provides a framework for understanding these skills in theory and practice, how they interact, and how they have been applied in healthcare, as well as avenues for future research
Emerging market for mobile remote physiological monitoring services
This paper offers an initial analysis of economic and market issues in the development and deployment of mobile remote physiological monitoring services for medical patients through wireless wearable sensors and actuators. Examining the characteristics of the service technologies and related industries, this study focuses on the structure, participants and roles of standardisation of the layers within the emerging mobile remote physiological monitoring industry. The study concludes that the structure of the emerging mobile remote physiological monitoring industry will be oriented about service provision, be integrated with other personal / patient data storage services and be heavily influenced by the interplay of technological developments, the health market structure, existing players and regulation. Additionally, the keys players are likely to be the system integrators and service providers concentrating on large institutional customers. A focus of the paper is analysing both the causes and implications of a modular, horizontally layered industry structure likely to result from the mix of technologies, suppliers and customers as this market develops. The paper discusses why, although horizontal specialisation is the most likely outcome, there is little risk of key layers becoming commoditised. The paper also discusses the appropriate types and levels of standardisation and equipment certification activities that should be encouraged, along with from which groups and industries the pressure for these will com
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