323 research outputs found

    From classical to quantum spintronics: Theory of coherent spin injection and spin valve phenomena

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    We present a theory of coherent quantum transport in ferromagnetic/ non-magnetic/ ferromagnetic heterojunctions. We predict quantum coherence to give rise to a quantum spin valve effect that, unlike its familiar classical analog, occurs even in the absence of a net spin current through the heterostructure. Thus the relationship between spin and charge transport is qualitatively different in the presence of quantum interference than in the (semi)classical regime. This has important implications for the design of quantum coherent spintronic devices and the interpretation of experiments.Comment: 5 pages, 2 figures. To appear in EP

    Development Status of a CVD System to Deposit Tungsten onto UO2 Powder via the WCI6 Process

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    Nuclear Thermal Propulsion (NTP) is under development for deep space exploration. NTP's high specific impulse (> 850 second) enables a large range of destinations, shorter trip durations, and improved reliability. W-60vol%UO2 CERMET fuel development efforts emphasize fabrication, performance testing and process optimization to meet service life requirements. Fuel elements must be able to survive operation in excess of 2850 K, exposure to flowing hydrogen (H2), vibration, acoustic, and radiation conditions. CTE mismatch between W and UO2 result in high thermal stresses and lead to mechanical failure as a result UO2 reduction by hot hydrogen (H2) [1]. Improved powder metallurgy fabrication process control and mitigated fuel loss can be attained by coating UO2 starting powders within a layer of high density tungsten [2]. This paper discusses the advances of a fluidized bed chemical vapor deposition (CVD) system that utilizes the H2-WCl6 reduction process

    (p)ppGpp and CodY promote Enterococcus faecalis virulence in a murine model of catheter-associated urinary tract infection

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    ABSTRACT In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in a catheter-associated urinary tract infection (CAUTI) mouse model and used global transcriptional analysis to investigate the relationship of (p)ppGpp and CodY. The absence of (p)ppGpp or single inactivation of codY led to lower bacterial loads in catheterized bladders and diminished biofilm formation on fibrinogen-coated surfaces under in vitro and in vivo conditions. Single inactivation of the bifunctional (p)ppGpp synthetase/hydrolase rel did not affect virulence, supporting previous evidence that the association of (p)ppGpp with enterococcal virulence is not dependent on the activation of the stringent response. Inactivation of codY in the (p)ppGpp0 strain restored E. faecalis virulence in the CAUTI model as well as the ability to form biofilms in vitro. Transcriptome analysis revealed that inactivation of codY restores, for the most part, the dysregulated metabolism of (p)ppGpp0 cells. While a clear linkage between (p)ppGpp and CodY with expression of virulence factors could not be established, targeted transcriptional analysis indicates that a possible association between (p)ppGpp and c-di-AMP signaling pathways in response to the conditions found in the bladder may play a role in enterococcal CAUTI. Collectively, data from this study identify the (p)ppGpp-CodY network as an important contributor to enterococcal virulence in catheterized mouse bladder and support that basal (p)ppGpp pools and CodY promote virulence through maintenance of a balanced metabolism under adverse conditions. IMPORTANCE Catheter-associated urinary tract infections (CAUTIs) are one of the most frequent types of infection found in the hospital setting that can develop into serious and potentially fatal bloodstream infections. One of the infectious agents that frequently causes complicated CAUTI is the bacterium Enterococcus faecalis, a leading cause of hospital-acquired infections that are often difficult to treat due to the exceptional multidrug resistance of some isolates. Understanding the mechanisms by which E. faecalis causes CAUTI will aid in the discovery of new druggable targets to treat these infections. In this study, we report the importance of two nutrient-sensing bacterial regulators, named (p)ppGpp and CodY, for the ability of E. faecalis to infect the catheterized bladder of mice

    Evaluación de calidad de agua en un sistema ribereño utilizado para riego agrícola de subsistencia

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    En la evaluación del impacto de la contaminación en el ambiente, existen diversas herramientas y técnicas que se aplican para conocer la calidad ambiental de los recursos naturales. El objetivo de este trabajo fue evaluar la calidad del agua en un sistema ribereño en San Luis Potosí, México asociado al impacto del uso agrícola, urbano e industrial. Fueron establecidos cinco puntos de muestreo asociado a diversos usos y descargas residuales en donde se evaluaron 28 muestras durante cuatro días de muestro. Estas fueron distribuidas a los 20, 40, 60, 80, 100 y 120 minutos del trayecto determinando con un medidor multiparámetro los sólidos disueltos totales (SDT), temperatura (T), conductividad eléctrica (CE), pH y oxígeno disuelto (OD). El resultado más destacado de las 28 muestras diarias y del total de 112 que los promedios oxígeno disuelto indican condición hipoxia que indica la desaparición de organismos y especies sensibles, concluyendo que el área ribereña requiere un constante monitoreo y diversificación de parámetros para evaluar su condición para actividades agrícolas.In the assessment of the impact of pollution on the environment, there are various tools and techniques that are applied to know the environmental quality of natural resources. The objective of this work was to evaluate water quality in a river system in San Luis Potosí, Mexico associated with the impact of agricultural, urban and industrial use. Five sampling points associated to various uses and residual discharges were established where 28 samples were evaluated during four days of sampling. The total dissolved solids (SDT), temperature (T), electrical conductivity (CE), pH and dissolved oxygen (OD) were distributed at 20, 40, 60, 80, 100 and 120 minutes of the path. The most outstanding result of the 28 daily samples and the total of 112 that dissolved oxygen averages indicate hypoxia condition indicating the disappearance of sensitive organisms and species, concluding that the riparian area requires constant monitoring and diversification of parameters to evaluate agricultural activities.Fil: Alcalá Jáuregui, J. A. Universidad Autónoma de San Luis Potosí. Facultad de AgronomíaFil: Acosta Doporto Geiler, A. Instituto Tecnológico Superior de los Ríos de Balancan (México)Fil: Rodríguez Ortiz, J.C. Universidad Autónoma de San Luis Potosí. Facultad de AgronomíaFil: Hernández Montoya, A. Universidad Autónoma de San Luis Potosí. Facultad de AgronomíaFil: Martínez Carretero, Eduardo. Consejo Nacional de Investigaciones Científicas y TécnicasFil: Filippini, Maria Flavia. Universidad Nacional de Cuyo. Facultad de Ciencias AgrariasFil: Díaz Flores, P. E. Universidad Autónoma de San Luis Potosí. Facultad de AgronomíaFil: Lara Mireles, J. L. Universidad Autónoma de San Luis Potosí. Facultad de Agronomí

    Spin transport of electrons through quantum wires with spatially-modulated strength of the Rashba spin-orbit interaction

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    We study ballistic transport of spin-polarized electrons through quantum wires in which the strength of the Rashba spin-orbit interaction (SOI) is spatially modulated. Subband mixing, due to SOI, between the two lowest subbands is taken into account. Simplified approximate expressions for the transmission are obtained for electron energies close to the bottom of the first subband and near the value for which anticrossing of the two lowest subbands occurs. In structures with periodically varied SOI strength, {\it square-wave} modulation on the spin transmission is found when only one subband is occupied and its possible application to the spin transistor is discussed. When two subbands are occupied the transmission is strongly affected by the existence of SOI interfaces as well as by the subband mixing

    Effect of bulk inversion asymmetry on the Datta-Das transistor

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    A model of the Datta-Das spin field-effect transistor is presented which, in addition to the Rashba interaction, takes into account the influence of bulk inversion asymmetry of zinc-blende semiconductors. In the presence of bulk inversion asymmetry, the conductance is found to depend significantly on the crystallographic orientation of the channel. We determine the channel direction optimal for the observation of the Datta-Das effect in GaAs and InAs-based devices.Comment: 4 pages, Revtex4, 4 EPS figure

    Ballistic spin-polarized transport and Rashba spin precession in semiconductor nanowires

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    We present numerical calculations of the ballistic spin-transport properties of quasi-one-dimensional wires in the presence of the spin-orbit (Rashba) interaction. A tight-binding analog of the Rashba Hamiltonian which models the Rashba effect is used. By varying the robustness of the Rashba coupling and the width of the wire, weak and strong coupling regimes are identified. Perfect electron spin-modulation is found for the former regime, regardless of the incident Fermi energy and mode number. In the latter however, the spin-conductance has a strong energy dependence due to a nontrivial subband intermixing induced by the strong Rashba coupling. This would imply a strong suppression of the spin-modulation at higher temperatures and source-drain voltages. The results may be of relevance for the implementation of quasi-one-dimensional spin transistor devices.Comment: 19 pages (incl. 9 figures). To be published in PR
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