Damage buildup in Si under bombardment with MeV heavy atomic and molecular ions

Accumulation of structural disorder in Si bombarded at −196 °C with 0.5 MeV ²⁰⁹Bi₁ and 1 MeV ²⁰⁹Bi₂ ions (the so-called molecular effect) is studied by Rutherford backscattering/channeling spectrometry. Results show that the damage buildup is sigmodal even for such heavy-ion bombardment at liquid nitrogen temperature. This strongly suggests that, for the implant conditions of this study, the buildup of lattice damage cannot be considered as an accumulation of completely disordered regions. Instead, damage-dose curves are well described by a cascade-overlap model modified to take into account a catastrophic collapse of incompletely disordered regions into an amorphous phase after damage reaches some critical level. Results also show that Bi₂ ions produce more lattice damage than Bi₁ ions implanted to the same dose. The ratio of lattice disorder produced by Bi₂ and Bi₁ ions is 1.7 near the surface, decreases with depth, and finally becomes close to unity in the bulk defect peak region. Parameters of collision cascades obtained using ballistic calculations are in good agreement with experimental data. The molecular effect is attributed to a spatial overlap of (relatively dense) collision subcascades, which gives rise to (i) nonlinear energy spike processes and/or (ii) an increase in the defect clustering efficiency with an effective increase in the density of ion-beam-generated defects.Research at StPSTU was supported in part by the Ministry for General and Professional Education of the Russian Federation

Studies of the structure and functions of blood cells in senile patients with pneumonia on the biological model of hypoxia by scanning probe microscopy

Biological model of hypoxia can be used for the diagnosis of functional changes in human erythrocytes under the effect of the hypoxic factor. The use of this model together with modern methods of scanning probe microscopy for evaluation of the severity of pulmonological disease in senile patients will help to predict treatment efficiency and outcom

Instantaneous pitch estimation algorithm based on multirate sampling

The paper presents an algorithm for accurate pitch estimation that takes advantage of the sinusoidal model with instantaneous parameters. The algorithm decomposes the signal into subband components, extracts their instantaneous parameters and evaluates period candidate generating function (PCGF). In order to achieve high accuracy for low and high-pitched sounds it is assumed that possible pitch variation range is proportional to current pitch value. The bandwidths of the decomposition filters and length of the analysis frame are scaled for each period candidate by multirate sampling. The algorithm is compared to other widely used pitch extractors on artificial quasiperiodic signals and natural speech. The proposed algorithm shows a remarkable frequency and time resolution for pitch-modulated sounds and performs well both in clean and noisy conditions

Fundamentos del enfoque de sistemas para la metodología de evaluación de instalaciones de obras acuáticas en medio natural

De acuerdo con los requisitos reglamentarios y ambientales sobre el funcionamiento de las instalaciones sanitarias denominadas objetos de actividad, se debe evaluar la influencia ambiental de estas instalaciones. en términos de utilización de los recursos hídricos, que es exactamente el objetivo de este estudio. Los fundamentos de la metodología de esta evaluación se desarrollan mediante el enfoque de sistema centrado en la noción de sistema. Los resultados del estudio de la interacción del objeto de actividad (OA) con los ambientes naturales (NENV) del geosistema de cuenca se utilizan en el desarrollo de los fundamentos de la metodología de evaluación de la influencia ambiental (EIA). Los resultados del estudio se han utilizado para diseñar y construir instalaciones de ingeniería hidroeléctrica en el norte del Cáucaso en el sur de Rusi

ОБРАБОТКА РЕЧЕВЫХ СИГНАЛОВ В ПРИЛОЖЕНИЯХ МУЛЬТИМЕДИА НА ОСНОВЕ ПЕРИОДИЧЕСКОЙ МОДЕЛИ С НЕСТАЦИОНАРНЫМИ ПАРАМЕТРАМИ

Methods of time-varying speech parameterization for analysis, processing and synthesis in multimedia systems. The main theoretical points are given and practical issues are discussed. Some practical results of instantaneous pitch estimation and quality of voice morphing are presented.Рассматриваются методы нестационарной параметризации речевых сигналов, позволяющие выполнять анализ, обработку и синтез речи в приложениях мультимедиа. Формулируются основные теоретические положения и рассматриваются вопросы практической реализации. Приводятся результаты применения методов к задачам оценки основного тона и изменения просодических характеристик речевого сигнала

PREDICTION OF METASTATIC DAMAGE OF REGIONAL LYMPHATIC NODES IN PATIENTS WITH BREAST CANCER

Purpose of the study. Solving the problem of searching for prognostic factors of metastatic lesion of regional lymph nodes among the morphological and molecular characteristics of the primary breast tumor will bring modern oncology closer to finding the optimal model for individualizing diagnosis and treatment of breast cancer.Materials and methods. The statistical analysis of clinical data and morphological factors obtained in the oncology department of the breast pathology of the Voronezh regional clinical oncological dispensary during a comprehensive study involving 223 patients was carried out. Only the stages I T1N0M0 and IIa T2N0M0 were taken into account.Results and discussion. The study found that patients with a lack of metastases are characterized by a relatively smaller average tumor size (20.43 ± 9.28 mm) than in patients with metastases (27.43 ± 12.4 mm), with 25 % of them having Size ≤10 mm, 50 % – from 10 to 34 mm and 25 % – ≥ 34 mm. The difference in groups on the basis of “age” is absent. A statistical relationship (p < 0.05) between the biological tumor subtype and its histological diagnosis, between the biological tumor subtype and histological diagnosis and the absence / presence of metastases in the lymph nodes (p <0.0001) was established.Conclusions. Thus, it was established that the histological and morphological study of the primary tumor provides the necessary information not only to determine its sensitivity to different types of systemic treatment and the choice of therapeutic tactics, but also to solve the problem of predicting the metastatic lesion of regional lymph nodes in breast cancer patients

КОНЦЕПЦІЯ МОБІЛЬНОЇ ЛАБОРАТОРІЇ КОМПЛЕКСНОЇ ОЦІНКИ ТА ПРОГНОЗУВАННЯ НАДЗВИЧАЙНИХ СИТУАЦІЙ

The concept of elaboration of mobile laboratories of integrated assessment and forecasting of emergency situations was developed. They provide operational radiation control in routine and emergency situations, remote and contact monitoring of concentration of harmful chemical contaminants in the atmosphere, soil, water, food, forage, etc. High technology equipment in theselaboratories enables to carry out assessment of the integral man-made and natural risks, to anticipate arising and development of emergency situations promptly, to forecast development and implementation of priority measures, to mitigate and eliminate potential effects of accidents and disasters.Розроблена концепція зі створення мобільних лабораторій комплексної оцінки та прогнозування надзвичайних ситуацій, які забезпечать оперативний радіаційний контроль в штатних і аварійних ситуаціях, дистанційний і контактний контроль концентрацій шкідливих хімічних домішок в атмосфері, ґрунті, воді, продуктах харчування, кормах та ін. Наукомістка апаратура таких лабораторій дає можливість проводити інтегральну оцінку техногенних і природних ризиків, прогнозувати виникнення та розвиток надзвичайних ситуацій, оперативно здійснювати розробку і впровадження першочергових заходів з ліквідації та пом'якшення можливих наслідків аварій і катастроф

ЦИФРОВЫЕ БАНКИ ФИЛЬТРОВ ДЛЯ СОВРЕМЕННЫХ ЗАДАЧ ОБРАБОТКИ ЗВУКОВЫХ СИГНАЛОВ

The paper reviews techniques of digital filter bank synthesis that can be applied for contemporary speech processing challenges. The paper describes practical experience of using digital filter banks in original systems of sound processing, namely, musical player with noise-aware audio enhancement and hearing aid application for a smartphone.В работе выполнен обзор способов синтеза цифровых банков фильтров, которые могут применяться для решения современных прикладных задач обработки звуковых сигналов. Описывается практический опыт использования цифровых банков фильтров в оригинальных системах обработки звука: музыкальном плеере с функцией повышения разборчивости звучания при прослушивании в шумной акустической обстановке, а также слуховом аппарате на базе смартфона

Association between antiarrhythmic, electrophysiological and antioxidative effects of melatonin in ischemia/reperfusion

Melatonin is assumed to confer cardioprotective action via antioxidative properties. We evaluated the association between ventricular tachycardia and/or ventricular fibrillation (VT/VF) incidence, oxidative stress, and myocardial electrophysiological parameters in experimental ischemia/reperfusion under melatonin treatment. Melatonin was given to 28 rats (10 mg/kg/day, orally, for 7 days) and 13 animals received placebo. In the anesthetized animals, coronary occlusion was induced for 5 min followed by reperfusion with recording of unipolar electrograms from ventricular epicardium with a 64-lead array. Effects of melatonin on transmembrane potentials were studied in ventricular preparations of 7 rats in normal and ?ischemic? conditions. Melatonin treatment was associated with lower VT/VF incidence at reperfusion, shorter baseline activation times (ATs), and activation-repolarization intervals and more complete recovery of repolarization times (RTs) at reperfusion (less baseline-reperfusion difference, ΔRT) (p < 0.05). Superoxide dismutase (SOD) activity was higher in the treated animals and associated with ΔRT (p = 0.001), whereas VT/VF incidence was associated with baseline ATs (p = 0.020). In vitro, melatonin led to a more complete restoration of action potential durations and resting membrane potentials at reoxygenation (p < 0.05). Thus, the antioxidative properties of melatonin were associated with its influence on repolarization duration, whereas the melatonin-related antiarrhythmic effect was associated with its oxidative stress-independent action on ventricular activation.Fil: Sedova, Ksenia A.. Czech Technical University In Prague; República ChecaFil: Bernikova, Olesya G.. Ural Branch of Russian Academy of Sciences; RusiaFil: Cuprova, Julia I.. Czech Technical University In Prague; República ChecaFil: Ivanova, Alexandra D.. Lomonosov Moscow State University; RusiaFil: Kutaeva, Galina A.. Pitirim Sorokin Syktyvkar State University; RusiaFil: Pliss, Michael G.. Almazov National Medical Research Centre; RusiaFil: Lopatina, Ekaterina V.. University of Saint Petersburg; RusiaFil: Vaykshnorayte, Marina A.. Ural Branch Of Russian Academy Of Sciences; RusiaFil: Diez, Emiliano Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Medicas. Instituto de Fisiologia; ArgentinaFil: Azarov, Jan E.. Ural Branch of Russian Academy of Sciences; Rusia. Pitirim Sorokin Syktyvkar State University; Rusi

System for wireless power transfer

Поступила: 15.02.2021. Принята в печать: 10.03.2021.Received: 15.02.2021. Accepted: 10.03.2021.Рассмотрены вопросы беспроводной передачи энергии на малые расстояния. Подход может быть применим для беспроводной зарядки батарей беспилотных транспортных средств. Предлагается для передачи энергии использовать технику микрополосковых структур. При приближении микрополосковых структур друг к другу с лицевой части они образуют направленный ответвитель на симметричных полосковых линиях. Длина линий взаимодействия выбирается в несколько раз большей, чем четверть длины волны. Балластные сопротивления из схемы исключаются. Такой подход приводит к малым потерям передачи энергии при изменении расстояния между микрополосковыми структурами в широких пределах. Осуществлено моделирование работы системы передачи энергии, изготовлен экспериментальный образец и проведены экспериментальные исследования. Моделирование и эксперимент хорошо согласуются друг с другом.The issues of wireless power transfer over short distances are considered. The approach may be used for wireless charging of batteries in unmanned vehicles. It is proposed to use the technique of microstrip structures for power transfer. The microstrip structures form a directional coupler on symmetrical strip lines when approaching by front parts. The length of the interaction lines is chosen several times longer than a quarter of the wavelength. Ballast resistors are excluded from the circuit. This approach leads to small losses of power transfer when the distance between microstrip structures changes over a wide range. Modeling of the operation of the power transfer system has been carried out, an experimental sample has been made and experimental studies have been carried out. The simulation and experiment are well accorded.Работа выполнена при поддержке РФФИ и Севастопольского региона, проект № 20-48-920001.The research is carried out with the financial support of the RFBR and the Sevastopol region, project № 20-48-920001