Influence du Procede de Fabrication sur la Conformite aux Normes des Produits d’une Boyauderie Industrielle au Centre du Maroc

L'industrie de boyauderie a connu un développement prodigieux ces derniers temps au Maroc. Cette situation exige une conformité des produits de boyauderie destinés à l'exportation, étant donné que les produits de charcuterie sont souvent soumis à de multiples sources de contamination liées à la longueur et à la complexité de leur cheminement, c'est-à-dire, de l'étable à la table. Afin d'évaluer la qualité hygiénique des boyaux, des analyses microbiologiques ont été réalisées sur 7 lots différents de boyaux, à des stades différents de traitement dans une unité de boyauderie, au centre du Maroc. Les résultats montrent que tous les échantillons analysés durant les étapes de mesurage, égouttage et salage ont été conformes. Cependant, les étapes du calibrage, tubage et conditionnement ont présenté un pourcentage de non- conformité de 28,6, 42,9 et 14,3 %, respectivement. La non-conformité des échantillons analysés a été liée principalement à la présence de coliformes totaux et fécaux. Cette contamination fécal a sans doute été causée par le non-respect des règles d'hygiène au niveau des ateliers de production et/ou par les manipulateurs et pourrait être à l'origine d'un risque sanitaire. L'évaluation du microbisme bactérien a révélé que le calibrage, le tubage et le conditionnement sont des étapes critiques, dont la maîtrise est nécessaire pour assurer la conformité du produit fini. Ce qui traduit la nécessité d'instaurer un système de contrôle qualité.Mots clés : Boyaux, qualité hygiénique, analyses, risque sanitaire, conformité, Maro

Efficacy of once daily darunavir/ritonavir 800/100 mg in PI/r-experienced HIV-1 infected patients with suppressed HIV-1 replication: the RADAR study

International audiencen.

Operational framework based on modeling languages to support product repository implementation.

Part 3: Tools and MethodologiesInternational audienceEmbracing Product Lifecycle Management approach involves integrating a product repository in the company information system. From customer's needs to disposal stage, several product representations exist. The product repository purpose is to secure consistency of one product representation with the others. This paper presents an operational modeling framework that supports product repository implementation. In order to ensure consistency, this framework identifies correspondences between entities of languages (“trade” languages and standard languages). The presented concepts are illustrated with correspondences between language entities of product designed and productplanned to be built Bills of Materials

Mechanisms explaining transitions between tonic and phasic firing in neuronal populations as predicted by a low dimensional firing rate model

Several firing patterns experimentally observed in neural populations have been successfully correlated to animal behavior. Population bursting, hereby regarded as a period of high firing rate followed by a period of quiescence, is typically observed in groups of neurons during behavior. Biophysical membrane-potential models of single cell bursting involve at least three equations. Extending such models to study the collective behavior of neural populations involves thousands of equations and can be very expensive computationally. For this reason, low dimensional population models that capture biophysical aspects of networks are needed. \noindent The present paper uses a firing-rate model to study mechanisms that trigger and stop transitions between tonic and phasic population firing. These mechanisms are captured through a two-dimensional system, which can potentially be extended to include interactions between different areas of the nervous system with a small number of equations. The typical behavior of midbrain dopaminergic neurons in the rodent is used as an example to illustrate and interpret our results. \noindent The model presented here can be used as a building block to study interactions between networks of neurons. This theoretical approach may help contextualize and understand the factors involved in regulating burst firing in populations and how it may modulate distinct aspects of behavior.Comment: 25 pages (including references and appendices); 12 figures uploaded as separate file

Contribution to the Study of the Mass Reduction of Stones by Some Medicinal Plants

ABSTRACT: The cystine calculi's, consisting primarily of amino acids, is considered the rarest stones with a prevalence of 1% with adults and 10% with the gallstone child. Its treatment is difficult because of its resistance to extracorporeal lithotripsy and its frequent recurrence. Drug treatments used until now, based on citrate are effective, but often poorly tolerated. Morocco is one of the countries that has been using, for a long time, traditional medicine based on natural plants to treat many diseases including stones. Material and methods: In 1L saline solution containing 9 g / L of NaCl and boiled, is introduced 5 g of plant extract powder. The powder is left soaked for 15 minutes and then filtered. A specific installation that resembles the urinary circuit was conducted in the laboratory. As a result, the cystine stone is placed in a tube then undergoes a steady flow through a dynamic circuit, the solution laden with extract for eight weeks; as an effective time to treat gallstones. [1] Every two weeks, the calculations are removed and dried for 16 hours at a temperature of 40 ° C. The same assembly was carried out for two other witnesses solutions to correct the loss mass (Dissolution Rate): The first is a solution of Potassium Citrate of 3 mmol / L and the second is NaCl of 9 g / L. Results: After eight weeks, the loss mass is about (61,43±11,12) % with. ( HHL ) , (63,75±10,95) % to ( OFI ) , (66,83±11,12) % to (AVL ) and (72,46±11,07) % to ( SZM ), while the loss of mass in the presence of witnesses solutions is (20,23±3,12) %for potassium citrate ( C Pot ) and (18,38±5,32) %for the saline solutions