ABSTRACT: The cystine calculi's, consisting primarily of amino acids, is considered the rarest stones with a prevalence of 1% with adults and 10% with the gallstone child. Its treatment is difficult because of its resistance to extracorporeal lithotripsy and its frequent recurrence. Drug treatments used until now, based on citrate are effective, but often poorly tolerated. Morocco is one of the countries that has been using, for a long time, traditional medicine based on natural plants to treat many diseases including stones. Material and methods: In 1L saline solution containing 9 g / L of NaCl and boiled, is introduced 5 g of plant extract powder. The powder is left soaked for 15 minutes and then filtered. A specific installation that resembles the urinary circuit was conducted in the laboratory. As a result, the cystine stone is placed in a tube then undergoes a steady flow through a dynamic circuit, the solution laden with extract for eight weeks; as an effective time to treat gallstones. [1] Every two weeks, the calculations are removed and dried for 16 hours at a temperature of 40 ° C. The same assembly was carried out for two other witnesses solutions to correct the loss mass (Dissolution Rate): The first is a solution of Potassium Citrate of 3 mmol / L and the second is NaCl of 9 g / L. Results: After eight weeks, the loss mass is about (61,43±11,12) % with. ( HHL ) , (63,75±10,95) % to ( OFI ) , (66,83±11,12) % to (AVL ) and (72,46±11,07) % to ( SZM ), while the loss of mass in the presence of witnesses solutions is (20,23±3,12) %for potassium citrate ( C Pot ) and (18,38±5,32) %for the saline solutions