The Hamburg/ESO R-process Enhanced Star survey (HERES) IV. Detailed abundance analysis and age dating of the strongly r-process enhanced stars CS 29491-069 and HE 1219-0312

We report on a detailed abundance analysis of two strongly r-process enhanced, very metal-poor stars newly discovered in the HERES project, CS 29491-069 ([Fe/H]=-2.51, [r/Fe]=+1.1) and HE 1219-0312 ([Fe/H]=-2.96, [r/Fe]=+1.5). The analysis is based on high-quality VLT/UVES spectra and MARCS model atmospheres. We detect lines of 15 heavy elements in the spectrum of CS 29491-069, and 18 in HE 1219-0312; in both cases including the Th II 4019 {\AA} line. The heavy-element abundance patterns of these two stars are mostly well-matched to scaled solar residual abundances not formed by the s-process. We also compare the observed pattern with recent high-entropy wind (HEW) calculations, which assume core-collapse supernovae of massive stars as the astrophysical environment for the r-process, and find good agreement for most lanthanides. The abundance ratios of the lighter elements strontium, yttrium, and zirconium, which are presumably not formed by the main r-process, are reproduced well by the model. Radioactive dating for CS 29491-069 with the observed thorium and rare-earth element abundance pairs results in an average age of 9.5 Gyr, when based on solar r-process residuals, and 17.6 Gyr, when using HEW model predictions. Chronometry seems to fail in the case of HE 1219-0312, resulting in a negative age due to its high thorium abundance. HE 1219-0312 could therefore exhibit an overabundance of the heaviest elements, which is sometimes called an "actinide boost"

Commensurability and beyond: from Mises and Neurath to the future of the socialist calculation debate

Mises' 'calculation argument' against socialism argues that monetary calculation is indispensable as a commensurable unit for evaluating factors of production. This is not due to his conception of rationality being purely 'algorithmic,' for it accommodates non-monetary, incommensurable values. Commensurability is needed, rather, as an aid in the face of economic complexity. The socialist Neurath's response to Mises is unsatisfactory in rejecting the need to explore possible non-market techniques for achieving a certain degree of commensurability. Yet Neurath's contribution is valuable in emphasizing the need for a balanced, comparative approach to the question of market versus non-market that puts the commensurability question in context. These central issues raised by adversaries in the early socialist calculation debate have continued relevance for the contemporary discussion

Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

Rett syndrome (RTT) is a progressive neurodevelopmental disorder mainly caused by mutations in the X-linked MECP2 gene. RTT patients show multisystem disturbances associated with an oxinflammatory status. Inflammasomes are multi-protein complexes, responsible for host immune responses against pathogen infections and redox-related cellular stress. Assembly of NLRP3/ASC inflammasome triggers pro-caspase-1 activation, thus, resulting in IL-1β and IL-18 maturation. However, an aberrant activation of inflammasome system has been implicated in several human diseases. Our aim was to investigate the possible role of inflammasome in the chronic subclinical inflammatory condition typical of RTT, by analyzing this complex in basal and lipopolysaccharide (LPS)+ATP-stimulated primary fibroblasts, as well as in serum from RTT patients and healthy volunteers. RTT cells showed increased levels of nuclear p65 and ASC proteins, pro-IL-1β mRNA, and NLRP3/ASC interaction in basal condition, without any further response upon the LPS + ATP stimuli. Moreover, augmented levels of circulating ASC and IL-18 proteins were found in serum of RTT patients, which are likely able to amplify the inflammatory response. Taken together, our findings suggest that RTT patients exhibited a challenged inflammasome machinery at cellular and systemic level, which may contribute to the subclinical inflammatory state feedback observed in this pathology

Theorising Disability: Beyond Common Sense

This article seeks to introduce the topic of disability to political theory via a discussion of some of the literature produced by disability theorists. The author argues that these more radical approaches conceptualise disability in ways that conflict with ‘common-sense’ notions of disability that tend to underpin political theoretical considerations of the topic. Furthermore, the author suggests that these more radical conceptualisations have profound implications for current debates on social justice, equality and citizenship that highlight the extent to which these notions are also currently underpinned by ‘common-sense’ notions of ‘normality’

Partial-wave analysis of the eta pi+ pi- system produced in the reaction pi-p --> eta pi+ pi- n at 18 GeV/c

A partial-wave analysis of 9082 eta pi+ pi- n events produced in the reaction pi- p --> eta pi+ pi- n at 18.3 GeV/c has been carried out using data from experiment 852 at Brookhaven National Laboratory. The data are dominated by J^{PC} = 0^{-+} partial waves consistent with observation of the eta(1295) and the eta(1440). The mass and width of the eta(1295) were determined to be 1282 +- 5 MeV and 66 +- 13 Mev respectively while the eta(1440) was observed with a mass of 1404 +- 6 MeV and width of 80 +- 21 MeV. Other partial waves of importance include the 1++ and the 1+- waves. Results of the partial wave analysis are combined with results of other experiments to estimate f1(1285) branching fractions. These values are considerably different from current values determined without the aid of amplitude analyses.Comment: 22 pages, 8 figure

Observation of exotic meson production in the reaction π−p→η′π−p \pi^{-} p \to \eta^{\prime} \pi^- p at 18 GeV/c

An amplitude analysis of an exclusive sample of 5765 events from the reaction $\pi^{-} p \to \eta^{\prime} \pi^- p$ at 18 GeV/c is described. The $\eta^{\prime} \pi^-$ production is dominated by natural parity exchange and by three partial waves: those with $J^{PC} = 1^{-+}, 2^{++},$ and $4^{++}$. A mass-dependent analysis of the partial-wave amplitudes indicates the production of the $a_2(1320)$ meson as well as the $a_4(2040)$ meson, observed for the first time decaying to $\eta^{\prime}\pi^-$. The dominant, exotic (non-$q\bar{q})$ $1^{-+}$ partial wave is shown to be resonant with a mass of $1.597 \pm 0.010^{+0.045}_{-0.010}$ GeV/c^2 and a width of $0.340 \pm 0.040 \pm 0.050$ GeV/c^2 . This exotic state, the $\pi_1(1600)$, is produced with a $t$ dependence which is different from that of the $a_2(1320)$ meson, indicating differences between the production mechanisms for the two states.Comment: 5 pages with 4 figure

Evidence for Exotic J^{PC}=1^{-+} Meson Production in the Reaction pi- p --> eta pi- p at 18 GeV/c

Details of the analysis of the eta pi- system studied in the reaction pi^{-} p --> eta pi^{-} p at 18 GeV/c are given. Separate analyses for the 2 gamma and pi+ pi- pi0 decay modes of the eta are presented. An amplitude analysis of the data indicates the presence of interference between the a(2)(1320)- and a J^{PC}=1^{-+} wave between 1.2 and 1.6 GeV/c^2. The phase difference between these waves shows phase motion not attributable solely to the a(2)(1320)-. The data can be fitted by interference between the a(2)(1320)- and an exotic 1^{-+} resonance with M = 1370 +-16 +50 -30} MeV/c^2 and Gamma = 385 +- 40 +65 -105 MeV/c^2. Our results are compared with those of other experiments.Comment: 50 pages of text and 34 figure