РЕДКИЙ СЛУЧАЙ БРУЦЕЛЛЕЗНОГО МЕНИНГОЭНЦЕФАЛИТА

Nowadays, a rare case of brucellosis meningoencephalitis is presented. Indicated on the features of its clinical course, the various laboratory analyzes are adduced and the methods of rational therapy are discussed. Представлен редкий в наши дни случай бруцеллезного менингоэнцефалита. Указывается на особенности его клинического течения с поражением ЦНС, приводятся различные лабораторные анализы и обсуждаются методы рациональной терапии

To the question of the choice of operational methods of treatment of hydrocele in elderly patients

The article presents an analysis of the results of treatment of dropsy of the testicular membranes after traditional Winckelmann, Bergman operations and operations for dropsy of the testicle shells proposed by the authors, the working name of which is “Window”. It was found that the operation 'Window' causes fewer complications in the immediate and late postoperative periods: less pronounced pain syndrome, less often inflammatory complications such as orchitis and epididymitis occur as compared with traditional operations.В статье представлен анализ результатов лечения водянки оболочек яичка после традиционных операций Винкельмана, Бергмана и операций при водянке оболочек яичка предложенный авторами рабочее название которой 'Окошко'. Было установлено, что операция 'Окошко' вызывает меньше осложнений в ближайшем и отдаленном послеоперационном периодах: менее выраженный болевой синдром, реже возникают воспалительные осложнения в виде орхита и эпидидимита по сравнению с традиционными операциями

Клинико-морфологические особенности немышечноинвазивного рака мочевого пузыря: влияние на лечение, прогноз и рецидив заболевания (обзор литературы)

This review of bladder cancer describes modern clinical and pathologic features of the neoplasm, reports new data about treatment and prognosis of this disease.В настоящем обзоре описаны современные клинические и патоморфологические особенности рака мочевого пузыря, а также приведены данные о современных принципах лечения этого заболевания и критериях прогноза

ТЕЧЕНИЕ ЭПИДЕМИЧЕСКОГО ПАРОТИТА В ПЕРИОД ПОДЪЕМА ЗАБОЛЕВАЕМОСТИ, ПО ДАННЫМ РЕСПУБЛИКАНСКОГО ЦЕНТРА ИНФЕКЦИОННЫХ БОЛЕЗНЕЙ Г. МАХАЧКАЛЫ

The aim of the study was to study the course of epidemic parotitis in patients with a sharp increase in the incidence rate in Dagestan in 2017, and to analyze the coverage of vaccination against this infection.In the Republic of Dagestan, from January to December 2017, there was an increase in the incidence of mumps infection — 2,632 cases, in 2016 —148, in 2015 — 1 case. It turned out that 1492 (56.6%) of 2,632 patients with epidemic parotitis in 2017 were not vaccinated.Clinical and laboratory monitoring of 449 patients with epidemic parotitis hospitalized in the Republican Center for Infectious Diseases was carried out. The greatest number of cases was between the ages of 12 and 35 years. The clinical picture of parotitis infection in adults did not differ from that of children. First parotid glands are affected, then the lesions of other glandular organs are joined — pancreatitis (51.2%), orchitis (32%) and CNS — meningitis (16%). Outcomes of the disease were favorable. Цель исследования: изучить течение эпидемического паротита у больных при резком увеличении заболеваемости в Дагестане в 2017 г. и проанализировать охват вакцинацией против данной инфекции. В республике Дагестан с января по декабрь 2017 г. зарегистрировано повышение заболеваемости паротитной инфекцией — 2632 случая, в 2016 г. —148, в 2015 г. — 1 случай. Оказалось, что 1492 (56,6%) человека из 2632 заболевших в 2017 г. эпидемическим паротитом не были привиты. Проведено клинико-лабораторное наблюдение 449 больных эпидемическим паротитом, госпитализированных в Республиканский центр инфекционных болезней г. Махачкалы. Наибольшее количество заболевших было в возрасте от 12 до 35 лет. Клиническая картина паротитной инфекции у взрослых не отличалась от таковой у детей. Сначала поражаются околоушные слюнные железы, затем присоединяются поражения других железистых органов — панкреатит (51,2%), орхит (32%) и ЦНС — менингит (16%).  Исходы заболевания отмечались благоприятные

THE ONE UNCOMMON CASE OF BRUCELLOSIS MENINGOENCEPHALITIS

Nowadays, a rare case of brucellosis meningoencephalitis is presented. Indicated on the features of its clinical course, the various laboratory analyzes are adduced and the methods of rational therapy are discussed

THE COURSE OF EPIDEMIC PAROTITIS DURING THE PERIOD OF RISING MORBIDITY, ACCORDING TO THE REPUBLICAN CENTER FOR INFECTIOUS DISEASES IN MAKHACHKALA

The aim of the study was to study the course of epidemic parotitis in patients with a sharp increase in the incidence rate in Dagestan in 2017, and to analyze the coverage of vaccination against this infection.In the Republic of Dagestan, from January to December 2017, there was an increase in the incidence of mumps infection — 2,632 cases, in 2016 —148, in 2015 — 1 case. It turned out that 1492 (56.6%) of 2,632 patients with epidemic parotitis in 2017 were not vaccinated.Clinical and laboratory monitoring of 449 patients with epidemic parotitis hospitalized in the Republican Center for Infectious Diseases was carried out. The greatest number of cases was between the ages of 12 and 35 years. The clinical picture of parotitis infection in adults did not differ from that of children. First parotid glands are affected, then the lesions of other glandular organs are joined — pancreatitis (51.2%), orchitis (32%) and CNS — meningitis (16%). Outcomes of the disease were favorable

РЕДКИЙ СЛУЧАЙ БРУЦЕЛЛЕЗНОГО МЕНИНГОЭНЦЕФАЛИТА

Nowadays, a rare case of brucellosis meningoencephalitis is presented. Indicated on the features of its clinical course, the various laboratory analyzes are adduced and the methods of rational therapy are discussed. Представлен редкий в наши дни случай бруцеллезного менингоэнцефалита. Указывается на особенности его клинического течения с поражением ЦНС, приводятся различные лабораторные анализы и обсуждаются методы рациональной терапии.</p

A MULTICENTRE STUDY OF ASSESSING THE EFFECTIVENESS OF SALVAGING LYMPHADENECTOMY IN PATIENTS WITH PROSTATE CANCER WITH DISEASE PROGRESSION AFTER THE RADICAL TREATMENT

Prostate cancer (PC) is one of the most urgent problems of modern oncourology because of the continuing high incidence of this pathology. The main methods of radical treatment of patients with localized and locally advanced prostate cancer are radical prostatectomy (RP) and radiotherapy – remote (RRT) or brachytherapy.  However, the frequency of biochemical markers of disease progression after curative treatment is high and reaches up to 27–53%. It is extremely important to find the tumor lesion that leads to the increase of the marker. The  palliative hormone therapy (PHT) was the only accepted method in patients with occurrence of distant metastases in recent time. However, a significant number of patients relapse marker may be associated with the so-called oligo-metastatic disease progression, in which the number of detected metastatic lesions is minimal. As the results of the research, the use of surgical or radiological treatment in selected patients of this cohort can significantly increase the length of time prior to the appointment of HT, and in some cases completely abandon its holding.Purpose. To evaluate the results of the saving pelvic lymphadenectomy in patients with prostate cancer with disease progression after radical therapies.Patients and methods. The article summarizes the results of surgical treatment of patients who have undergone life-saving lymphadenectomy about oligo-nodal metastatic progression of prostate cancer after treatment in 3 centers – P. Hertsen MORI, the branch of NMRRC; N. Petrov Research Institute of Oncology and Russian scientific center of radiology and surgical technologies. In this multicenter study they evaluated the immediate and remote results of surgical treatment of 57 patients.Results. The results performed the high efficiency of the method of the saving pelvic lymphadenectomy in patients with prostate cancer with disease progression after radical treatment. So, response to therapy and reduction in the marker level was observed in 47 (82.5%) patients. The decline in PSA level ≥50% from initial level in a month after the operation was in 38 (66,7%) patients. A complete answer in the form of lower marker ≤0.2 ng/ml was observed in 13 (22,8%) patients. For the entire median follow-up period of 12 months, patients with complete response to therapy had received any hormonal treatment.Conclusion. The saving pelvic lymphadenectomy is an effective method for the treatment of patients with the presence of lymphogenic progression of prostate cancer after a radical treatment with satisfactory oncological results. A significant contingent of patients, SLE is associated with good response to therapy and reduction in PSA levels and long disease-free period. In some patients the removal of nodal metastases allows to postpone or to abandon the HT and hope to increase overall survival of patients

ТЕЧЕНИЕ ЭПИДЕМИЧЕСКОГО ПАРОТИТА В ПЕРИОД ПОДЪЕМА ЗАБОЛЕВАЕМОСТИ, ПО ДАННЫМ РЕСПУБЛИКАНСКОГО ЦЕНТРА ИНФЕКЦИОННЫХ БОЛЕЗНЕЙ Г. МАХАЧКАЛЫ

The aim of the study was to study the course of epidemic parotitis in patients with a sharp increase in the incidence rate in Dagestan in 2017, and to analyze the coverage of vaccination against this infection.In the Republic of Dagestan, from January to December 2017, there was an increase in the incidence of mumps infection — 2,632 cases, in 2016 —148, in 2015 — 1 case. It turned out that 1492 (56.6%) of 2,632 patients with epidemic parotitis in 2017 were not vaccinated.Clinical and laboratory monitoring of 449 patients with epidemic parotitis hospitalized in the Republican Center for Infectious Diseases was carried out. The greatest number of cases was between the ages of 12 and 35 years. The clinical picture of parotitis infection in adults did not differ from that of children. First parotid glands are affected, then the lesions of other glandular organs are joined — pancreatitis (51.2%), orchitis (32%) and CNS — meningitis (16%). Outcomes of the disease were favorable. Цель исследования: изучить течение эпидемического паротита у больных при резком увеличении заболеваемости в Дагестане в 2017 г. и проанализировать охват вакцинацией против данной инфекции. В республике Дагестан с января по декабрь 2017 г. зарегистрировано повышение заболеваемости паротитной инфекцией — 2632 случая, в 2016 г. —148, в 2015 г. — 1 случай. Оказалось, что 1492 (56,6%) человека из 2632 заболевших в 2017 г. эпидемическим паротитом не были привиты. Проведено клинико-лабораторное наблюдение 449 больных эпидемическим паротитом, госпитализированных в Республиканский центр инфекционных болезней г. Махачкалы. Наибольшее количество заболевших было в возрасте от 12 до 35 лет. Клиническая картина паротитной инфекции у взрослых не отличалась от таковой у детей. Сначала поражаются околоушные слюнные железы, затем присоединяются поражения других железистых органов — панкреатит (51,2%), орхит (32%) и ЦНС — менингит (16%).  Исходы заболевания отмечались благоприятные