52 research outputs found
Π Π°Π±ΠΎΡΠ°Ρ ΠΏΠ°ΡΠ° "LiCl/ΠΌΠ½ΠΎΠ³ΠΎΡΠ»ΠΎΠΉΠ½ΡΠ΅ ΡΠ³Π»Π΅ΡΠΎΠ΄Π½ΡΠ΅ Π½Π°Π½ΠΎΡΡΡΠ±ΠΊΠΈ" - Π²ΠΎΠ΄Π° Π΄Π»Ρ Π·Π°ΠΏΠ°ΡΠ°Π½ΠΈΡ ΡΠ΅ΠΏΠ»ΠΎΠ²ΠΎΠΉ ΡΠ½Π΅ΡΠ³ΠΈΠΈ: ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ
Π‘ΠΎΡΠ±ΡΠΈΠΎΠ½Π½ΠΎΠ΅ Π·Π°ΠΏΠ°ΡΠ°Π½ΠΈΠ΅ ΡΠ΅ΠΏΠ»Π° (Π‘ΠΠ’) - ΠΎΠ΄Π½Π° ΠΈΠ· ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π΄Π»Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π²ΠΎΠ·ΠΎΠ±Π½ΠΎΠ²Π»ΡΠ΅ΠΌΡΡ
ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ² ΡΠ½Π΅ΡΠ³ΠΈΠΈ. ΠΠΎΠΌΠΏΠΎΠ·ΠΈΡΠ½ΡΠ΅ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΡΠΈΠΏΠ° "Π‘ΠΎΠ»Ρ Π² ΠΏΠΎΡΠΈΡΡΠΎΠΉ ΠΌΠ°ΡΡΠΈΡΠ΅" ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ ΠΈΠ½ΡΠ΅ΡΠ΅Ρ Π΄Π»Ρ Π‘ΠΠ’, ΡΠ°ΠΊ ΠΊΠ°ΠΊ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΡΡ Π²ΡΡΠΎΠΊΠΈΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΡΠΌΠΈ Π·Π°ΠΏΠ°ΡΠ°ΡΡΠ΅ΠΉ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ. ΠΠ΅Π΄Π°Π²Π½ΠΎ Π΄Π»Ρ Π‘ΠΠ’ Π±ΡΠ» ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½ Π½ΠΎΠ²ΡΠΉ ΡΠΎΡΠ±Π΅Π½Ρ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ Ρ
Π»ΠΎΡΠΈΠ΄Π° Π»ΠΈΡΠΈΡ ΠΈ ΠΌΠ½ΠΎΠ³ΠΎΡΠ»ΠΎΠΉΠ½ΡΡ
ΡΠ³Π»Π΅ΡΠΎΠ΄Π½ΡΡ
Π½Π°Π½ΠΎΡΡΡΠ±ΠΎΠΊ "LiCl/(ΠΠ£ΠΠ’)", Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΡΡΠΈΠΉΡΡ Π·Π°ΠΏΠ°ΡΠ°ΡΡΠ΅ΠΉ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡΡ 1,7 ΠΊΠΠΆ/Π³. ΠΠΎΠ²ΡΠΉ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΡΠΎΠ±ΠΎΠΉ ΠΏΠΎΡΠΎΡΠΎΠΊ, ΡΡΠΎ Π·Π°ΡΡΡΠ΄Π½ΡΠ΅Ρ Π΅Π³ΠΎ Π·Π°Π³ΡΡΠ·ΠΊΡ Π² ΡΠ΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΈΠΊ. ΠΠ°Π½Π½Π°Ρ ΡΠ°Π±ΠΎΡΠ° ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π°: 1) ΡΠΎΡΠΌΠΎΠ²Π°Π½ΠΈΡ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡΠ° Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΏΠΎΠ»ΠΈΠ²ΠΈΠ½ΠΈΠ»ΠΎΠ²ΠΎΠ³ΠΎ ΡΠΏΠΈΡΡΠ° Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΠ²ΡΠ·ΡΡΡΠ΅Π³ΠΎ; 2) ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠΎΡΠ±ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠ°Π²Π½ΠΎΠ²Π΅ΡΠΈΡ Π³ΡΠ°Π½ΡΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡΠ° Ρ ΠΏΠ°ΡΠ°ΠΌΠΈ Π²ΠΎΠ΄Ρ ΠΈ ΠΎΡΠ΅Π½ΠΊΠ° Π΅Π³ΠΎ Π·Π°ΠΏΠ°ΡΠ°ΡΡΠ΅ΠΉ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ; 3) ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΡΠΎΡΠ±ΡΠΈΠΈ Π²ΠΎΠ΄Ρ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΡΡΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠΈΠΊΠ»Π° Π‘ΠΠ’ Π½Π° Π½Π΅Π±ΠΎΠ»ΡΡΠΎΠΌ, Π½ΠΎ ΡΠ΅ΠΏΡΠ΅Π·Π΅Π½ΡΠ°ΡΠΈΠ²Π½ΠΎΠΌ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠ΅ ΡΠ΅Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΡΠ΅Π±ΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΏΠ»ΠΎΡΠΊΠΎΠ³ΠΎ ΡΠ΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΈΠΊΠ°; 4) ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠ΄Π΅Π»ΡΠ½ΠΎΠΉ ΠΌΠΎΡΠ½ΠΎΡΡΠΈ Π΄Π»Ρ ΡΡΠ°Π΄ΠΈΠΉ Π·Π°ΠΏΠ°ΡΠ°Π½ΠΈΡ ΠΈ Π²ΡΡΠ²ΠΎΠ±ΠΎΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ΅ΠΏΠ»Π°. ΠΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΊΡΠΈΠ²ΡΠ΅ ΡΠΎΡΠ±ΡΠΈΠΈ Π²ΠΎΠ΄Ρ ΠΏΠΎΠ΄ΡΠΈΠ½ΡΡΡΡΡ ΡΠΊΡΠΏΠΎΠ½Π΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎΠΌΡ Π·Π°ΠΊΠΎΠ½Ρ Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠΌ Π²ΡΠ΅ΠΌΠ΅Π½Π΅ΠΌ [tau]=90-300 Ρ. ΠΡΠΈ ΠΊΠΎΠ½Π²Π΅ΡΡΠΈΠΈ 0,8 ΡΠ΄Π΅Π»ΡΠ½Π°Ρ ΠΌΠΎΡΠ½ΠΎΡΡΡ Π΄Π»Ρ ΡΡΠ°Π΄ΠΈΠΈ Π²ΡΠ΄Π΅Π»Π΅Π½ΠΈΡ ΡΠ΅ΠΏΠ»Π° Π²Π°ΡΡΠΈΡΡΠ΅ΡΡΡ Π² Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½Π΅ 2,9-4,1 ΠΡ/Π³, Π΄Π»Ρ ΡΡΠ°Π΄ΠΈΠΈ Π·Π°ΠΏΠ°ΡΠ°Π½ΠΈΡ ΡΠ΅ΠΏΠ»Π° - 9,7-9,8 ΠΡ/Π³. ΠΡΡΠΎΠΊΠΈΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΡΠ΄Π΅Π»ΡΠ½ΠΎΠΉ ΠΌΠΎΡΠ½ΠΎΡΡΠΈ Π½Π°ΡΡΠ΄Ρ Ρ Π±ΠΎΠ»ΡΡΠΎΠΉ Π·Π°ΠΏΠ°ΡΠ°ΡΡΠ΅ΠΉ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡΡ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ·ΠΈΡΠ° Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΡΡ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠΏΠΎΠΌΡΠ½ΡΡΠΎΠ³ΠΎ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Π° Π΄Π»Ρ Π‘ΠΠ’
ΠΠ½Π°Π»ΠΈΠ· ΡΡΠ΅Π΄Π½Π΅Π³ΠΎ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠ° ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ² Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΠΎΡΡΡΡΠΌΠΈ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠΌΠΈ Π²ΠΈΡΡΡΠ½ΡΠΌΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΡΠΌΠΈ
Development of inflammatory bronkholegochny process in children is followed by the permanent changes in system of an eritron aggravating finally the phenomenaΒ of a hypoxia of bodies and fabrics. Work purpose: studying of average diameter of erythrocytes at children of early age, patients with pneumonia and ARVI.Β Determination of average diameter of erythrocytes was carried out by a diffraction method on identical structure of chaotic objects at 36 children with pneumoniaΒ and at 41 children with a ARVI aged from 4 months till 3 years. The control group was made by 20 almost healthy children of the same age. During the sharp periodΒ of a disease the average diameter of erythrocytes was authentically increased both at pneumonia, and at a ARVI. Reliable difference of these indicators whenΒ comparing a toxic syndrome at pneumonia and a ARVI is revealed. Thus, at children of early age, patients with pneumonia and ARVI, in dynamics of a disease theΒ natural changes of average diameter of erythrocytes having differential and diagnostic and predictive value are revealed.Π Π°Π·Π²ΠΈΡΠΈΠ΅ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π±ΡΠΎΠ½Ρ
ΠΎΠ»Π΅Π³ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π΅ΡΡΡ ΡΡΠΎΠΉΠΊΠΈΠΌΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ ΡΡΠΈΡΡΠΎΠ½Π°,Β ΡΡΡΠ³ΡΠ±Π»ΡΡΡΠΈΠΌΠΈ Π² ΠΊΠΎΠ½Π΅ΡΠ½ΠΎΠΌ ΠΈΡΠΎΠ³Π΅ ΡΠ²Π»Π΅Π½ΠΈΡ Π³ΠΈΠΏΠΎΠΊΡΠΈΠΈ ΠΎΡΠ³Π°Π½ΠΎΠ² ΠΈ ΡΠΊΠ°Π½Π΅ΠΉ. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠ΅Π΄Π½Π΅Π³ΠΎ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠ° ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ² ΡΒ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΠΠ ΠΠ. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΠ΅Π΄Π½Π΅Π³ΠΎ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠ° ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ² ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌΒ Π΄ΠΈΡΡΠ°ΠΊΡΠΈΠΈ Π½Π° ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΠ΅ Π±Π΅ΡΠΏΠΎΡΡΠ΄ΠΎΡΠ½ΡΡ
ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠ² Ρ 36 Π΄Π΅ΡΠ΅ΠΉ Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ Ρ 41 ΡΠ΅Π±Π΅Π½ΠΊΠ° Ρ ΠΠ ΠΠ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡΒ 4 ΠΌΠ΅ΡΡΡΠ΅Π² Π΄ΠΎ 3 Π»Π΅Ρ. ΠΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΡΡ Π³ΡΡΠΏΠΏΡ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 20 ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π΄Π΅ΡΠ΅ΠΉ ΡΠΎΠ³ΠΎ ΠΆΠ΅ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. Π ΠΎΡΡΡΡΠΉ ΠΏΠ΅ΡΠΈΠΎΠ΄ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΡΡΠ΅Π΄Π½ΠΈΠΉ Π΄ΠΈΠ°ΠΌΠ΅ΡΡ ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ² Π±ΡΠ» Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ ΠΏΠΎΠ²ΡΡΠ΅Π½ ΠΊΠ°ΠΊ ΠΏΡΠΈ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ, ΡΠ°ΠΊ ΠΈ ΠΏΡΠΈ ΠΠ ΠΠ. ΠΡΡΠ²Π»Π΅Π½ΠΎ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΠ΅ ΠΎΡΠ»ΠΈΡΠΈΠ΅ Π΄Π°Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΏΡΠΈ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΏΡΠΈ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΠ ΠΠ. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎΒ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΠΠ ΠΠ, Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ Π²ΡΡΠ²Π»Π΅Π½Ρ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΡΠ΅Π΄Π½Π΅Π³ΠΎ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠ° ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ², ΠΈΠΌΠ΅ΡΡΠΈΠ΅ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎ-Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅
Π Π΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎ-ΡΠΈΠ½ΡΠΈΡΠΈΠ°Π»ΡΠ½Π°Ρ Π²ΠΈΡΡΡΠ½Π°Ρ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΡ Ρ Π΄Π΅ΡΠ΅ΠΉ. Π ΠΎΠ»Ρ Π² ΡΡΡΡΠΊΡΡΡΠ΅ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-ΠΈΠΌΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ
Acute respiratory infections (ARI) consistently occupy a leading place in the structure of infectious pathology, especially among children. The spectrum of pathogens is usually determined by the season and age aspect of the observed. In a large number of respiratory viruses, respiratory syncytial virus (RSV) occupies a special place due to the variety and severity of clinical manifestations of the disease caused by it in young children. This article is devoted to the analysis of the clinical course of RSV infection in children, the study of the features of the immune status against the background of this disease.It was found that in most cases of RSV infection in children was characterized by signs of bronchial obstruction syndrome and as a consequence in this group of children were found to have dysfunction of the immune system and reduction in the total number of T-lymphocytes, the hyperactivation In-cell component of adaptive immunity, manifested disimmunoglobulinemia (increase in the content of total IgE at lower IgA and IgG), that is, with the formation of immunodeficiency states from T- and B-cell links of adaptive immunity, with long-term recovery of impaired performance, even against the background of effective antiviral therapy.ΠΡΡΡΡΠ΅ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠ΅ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ (ΠΠ Π) Π½Π΅ΠΈΠ·ΠΌΠ΅Π½Π½ΠΎ Π·Π°Π½ΠΈΠΌΠ°ΡΡ Π²Π΅Π΄ΡΡΠ΅Π΅ ΠΌΠ΅ΡΡΠΎ Π² ΡΡΡΡΠΊΡΡΡΠ΅ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ, ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ ΡΡΠ΅Π΄ΠΈ Π΄Π΅ΡΠ΅ΠΉ. Π‘ΠΏΠ΅ΠΊΡΡ Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ, ΠΊΠ°ΠΊ ΠΏΡΠ°Π²ΠΈΠ»ΠΎ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½ ΡΠ΅Π·ΠΎΠ½ΠΎΠΌ ΠΈ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΠΌ Π°ΡΠΏΠ΅ΠΊΡΠΎΠΌ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΠΌΡΡ
. Π ΠΌΠ½ΠΎΠ³ΠΎΡΠΈΡΠ»Π΅Π½Π½ΠΎΠΌ ΡΡΠ΄Ρ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΡ
Π²ΠΈΡΡΡΠΎΠ², ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎ-ΡΠΈΠ½ΡΠΈΡΠΈΠ°Π»ΡΠ½ΡΠΉ Π²ΠΈΡΡΡ (Π Π‘Π) Π·Π°Π½ΠΈΠΌΠ°Π΅Ρ ΠΎΡΠΎΠ±ΠΎΠ΅ ΠΌΠ΅ΡΡΠΎ Π² ΡΠ²ΡΠ·ΠΈ Ρ ΠΌΠ½ΠΎΠ³ΠΎΠΎΠ±ΡΠ°Π·ΠΈΠ΅ΠΌ ΠΈ ΡΡΠΆΠ΅ΡΡΡΡ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΠΉ Π²ΡΠ·ΡΠ²Π°Π΅ΠΌΠΎΠΉ ΠΈΠΌ Π±ΠΎΠ»Π΅Π·Π½ΠΈ Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. ΠΠ°Π½Π½Π°Ρ ΡΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΠΈΠ·Ρ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅ΡΠ΅Π½ΠΈΡ Π Π‘Π ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ Ρ Π΄Π΅ΡΠ΅ΠΉ, ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° Π½Π° ΡΠΎΠ½Π΅ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ.ΠΡΠ»ΠΎ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ Π² Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²Π΅ ΡΠ»ΡΡΠ°Π΅Π² Π Π‘Π ΠΈΠ½ΡΠ΅ΠΊΡΠΈΡ Ρ Π΄Π΅ΡΠ΅ΠΉ ΠΏΡΠΎΡΠ΅ΠΊΠ°Π»Π° Ρ ΠΏΡΠΈΠ·Π½Π°ΠΊΠ°ΠΌΠΈ Π±ΡΠΎΠ½Ρ
ΠΎΠΎΠ±ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΈ ΠΊΠ°ΠΊ ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ Ρ Π΄Π°Π½Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π΄Π΅ΡΠ΅ΠΉ Π±ΡΠ»Π° Π²ΡΡΠ²Π»Π΅Π½Π° Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Π² Π²ΠΈΠ΄Π΅ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΠΎΠ±ΡΠ΅Π³ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° Π’-Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ², Π³ΠΈΠΏΠ΅ΡΠ°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π-ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ Π·Π²Π΅Π½Π° Π°Π΄Π°ΠΏΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡΠ½ΠΈΡΠ΅ΡΠ°, ΠΏΡΠΎΡΠ²Π»ΡΡΡΠ΅ΠΉΡΡ Π΄ΠΈΡΠΈΠΌΠΌΡΠ½ΠΎΠ³Π»ΠΎΠ±ΡΠ»ΠΈΠ΅ΠΌΠΈΠ΅ΠΉ (ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΠΎΠ±ΡΠ΅Π³ΠΎ IgΠ ΠΏΡΠΈ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠΈ IgA ΠΈ IgG), ΡΠΎ Π΅ΡΡΡ Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΈΠΌΠΌΡΠ½ΠΎΠ΄Π΅ΡΠΈΡΠΈΡΠ½ΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΡΠΎ ΡΡΠΎΡΠΎΠ½Ρ Π’- ΠΈ Π-ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ Π·Π²Π΅Π½ΡΠ΅Π² Π°Π΄Π°ΠΏΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡΠ½ΠΈΡΠ΅ΡΠ°, Ρ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΡΠΌ Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΠ΅ΠΌ Π½Π°ΡΡΡΠ΅Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ, Π΄Π°ΠΆΠ΅ Π½Π° ΡΠΎΠ½Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠΉ ΠΏΡΠΎΡΠΈΠ²ΠΎΠ²ΠΈΡΡΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ
ΠΠ¦ΠΠΠΠ Π£Π ΠΠΠΠ― ΠΠΠΠΠΠ£Π Π‘Π ΠΠΠΠΠ Π ΠΠΠΠΠΠ ΠΠΠ‘Π‘Π« Π ΠΠΠΠ’ΠΠΠΠ Π£ ΠΠΠ’ΠΠ Π ΠΠΠΠΠΠ ΠΠΠΠ ΠΠ‘Π’Π ΠΠ Π ΠΠΠΠΠΠΠΠΠ Π ΠΠ ΠΠ
Metabolic disorders lead to admission into the bloodstream of a large number of toxic substances medium molecular weight, the concentration of which increases in respiratory diseases. Objective: determine the level of molecules of average and low mass, peptides in the serum of in infants with pneumonia and ARVI. Determination of the level of molecules of average and low weight, and the content of the peptides in the serum was performed screening methodin infantswith pneumonia (31 children) and ARVI (37 children). There were 20 healthy children in control groupof the same age.In the acute period of the disease the level MSINM and peptides was significantly increased as in pneumonia, and ARVI. The highest values were observed during the study content of peptides. In addition to a clear dependence of the concentration of MSINM and peptides from the severity of infectious toxicosis found a significant difference between these parameters when comparing toxic syndrome with pneumonia and ARVI. Parameters of MSINM and peptides can be used as diagnostic criteria of pneumonia, ARVI and intensity of infection toxicosis.ΠΠ°ΡΡΡΠ΅Π½ΠΈΡ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ° ΠΏΡΠΈ ΠΠ ΠΠ ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡ ΠΊ ΠΏΠΎΡΡΡΠΏΠ»Π΅Π½ΠΈΡ Π² ΠΊΡΠΎΠ²ΠΎΡΠΎΠΊ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π²Π΅ΡΠ΅ΡΡΠ² ΡΡΠ΅Π΄Π½Π΅ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ°ΡΡΡ, ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΠΊΠΎΡΠΎΡΡΡ
ΡΠ²Π΅Π»ΠΈΡΠΈΠ²Π°Π΅ΡΡΡ ΠΏΡΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΡ
ΠΎΡΠ³Π°Π½ΠΎΠ² Π΄ΡΡ
Π°Π½ΠΈΡ. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΠΎΠ²Π½Ρ ΠΌΠΎΠ»Π΅ΠΊΡΠ» ΡΡΠ΅Π΄Π½Π΅ΠΉ ΠΈ Π½ΠΈΠ·ΠΊΠΎΠΉ ΠΌΠ°ΡΡΡ, ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ² Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΠΠ ΠΠ. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΠΎΠ²Π½Ρ ΠΌΠΎΠ»Π΅ΠΊΡΠ» ΡΡΠ΅Π΄Π½Π΅ΠΉ ΠΈ Π½ΠΈΠ·ΠΊΠΎΠΉ ΠΌΠ°ΡΡΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ² Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³-ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ (31 ΡΠ΅Π±Π΅Π½ΠΎΠΊ) ΠΈ ΠΠ ΠΠ (37 Π΄Π΅ΡΠ΅ΠΉ). ΠΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΡΡ Π³ΡΡΠΏΠΏΡ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 20 ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π΄Π΅ΡΠ΅ΠΉ ΡΠ°ΠΊΠΎΠ³ΠΎ ΠΆΠ΅ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. Π ΠΎΡΡΡΡΠΉ ΠΏΠ΅ΡΠΈΠΎΠ΄ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΡΡΠΎΠ²Π΅Π½Ρ ΠΠ‘ΠΠΠ ΠΈ ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ² Π±ΡΠ» Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ ΠΏΠΎΠ²ΡΡΠ΅Π½ ΠΊΠ°ΠΊ ΠΏΡΠΈ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ, ΡΠ°ΠΊ ΠΈ ΠΏΡΠΈ ΠΠ ΠΠ. ΠΠ°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΠΎΡΠΌΠ΅ΡΠ΅Π½Ρ ΠΏΡΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ². ΠΡΠΎΠΌΠ΅ ΡΠ΅ΡΠΊΠΎΠΉ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΠΠ‘ΠΠΠ ΠΈ ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ² ΠΎΡ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠΎΠΊΡΠΈΠΊΠΎΠ·Π°, Π²ΡΡΠ²Π»Π΅Π½ΠΎ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΠ΅ ΠΎΡΠ»ΠΈΡΠΈΠ΅ Π΄Π°Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΏΡΠΈ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΏΡΠΈ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΠ ΠΠ. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, Ρ Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΠΠ ΠΠ, Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ Π²ΡΡΠ²Π»Π΅Π½Ρ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΡΠΎΠ²Π½Ρ ΠΠ‘ΠΠΠ ΠΈ ΠΏΠ΅ΠΏΡΠΈΠ΄ΠΎΠ² Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ, ΠΈΠΌΠ΅ΡΡΠΈΠ΅ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎ-Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅
ΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ― Π ΠΠΠΠ ΠΠΠΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ― ΠΠ€Π€ΠΠΠ’ΠΠΠΠΠ‘Π’Π¬ ΠΠΠ’ΠΠΠΠΠ’ΠΠ ΠΠΠΠ¬ΠΠΠ Π’ΠΠ ΠΠΠΠ ΠΠ‘Π’Π Π«Π₯ ΠΠΠ¨ΠΠ§ΠΠ«Π₯ ΠΠΠ€ΠΠΠ¦ΠΠ Π‘ ΠΠΠΠΠΠΠΠΠ«Π Π’ΠΠΠΠ ΠΠΠΠ ΠΠ Π£ ΠΠΠ’ΠΠ
In the article results of a randomized comparative multicenter study of the clinical and microbiological efficacy and safety of azithromycin (Sumamed) and cefixime (Suprax) 185 children aged 1β14 years with moderate (70.8%) and severe forms (29.2%) of acute intestinal infections with invasive type of diarrhea. Etiological diagnosis microbiological method was detected in 48 (25.9%) patients, including salmonellosis in 85.4% of cases sonnei shigellosis or Flexner in 14.6% of patients. Found that both drugs have a high clinical efficacy (of 86.2% and 87.2%, respectively). While, microbiological efficacy of azithromycin was significantly higher (83.3%) than of cefixime (58.3%) (p < 0.001), including, when salmonellosis she reached 81.8% and that of cefixime, only 52.6% of patients. A clinical study confirmed the safe use of these antimicrobial agents in the treatment of acute intestinal infections in children.ΠΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π½Π΄ΠΎΠΌΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΌΠ½ΠΎΠ³ΠΎΡΠ΅Π½ΡΡΠΎΠ²ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ, ΠΌΠΈΠΊΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΠΈ Π°Π·ΠΈΡΡΠΎΠΌΠΈΡΠΈΠ½Π° (Π‘ΡΠΌΠ°ΠΌΠ΅Π΄) ΠΈ ΡΠ΅ΡΠΈΠΊΡΠΈΠΌΠ° (Π‘ΡΠΏΡΠ°ΠΊΡ) Ρ 185 Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 1β14 Π»Π΅Ρ ΠΏΡΠΈ ΡΡΠ΅Π΄Π½Π΅ΡΡΠΆΠ΅Π»ΡΡ
(70,8%) ΠΈ ΡΡΠΆΠ΅Π»ΡΡ
ΡΠΎΡΠΌΠ°Ρ
(29,2%) ΠΎΡΡΡΡΡ
ΠΊΠΈΡΠ΅ΡΠ½ΡΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ (ΠΠΠ) Ρ ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΠΌ ΡΠΈΠΏΠΎΠΌ Π΄ΠΈΠ°ΡΠ΅ΠΈ. ΠΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΠ· ΠΌΠΈΠΊΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ Ρ 48 (25,9%) Π±ΠΎΠ»ΡΠ½ΡΡ
, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ β ΡΠ°Π»ΡΠΌΠΎΠ½Π΅Π»Π»Π΅Π· Π² 85,4% ΡΠ»ΡΡΠ°Π΅Π², ΡΠΈΠ³Π΅Π»Π»Π΅Π· ΠΠΎΠ½Π½Π΅ ΠΈΠ»ΠΈ Π€Π»Π΅ΠΊΡΠ½Π΅ΡΠ° Ρ 14,6% Π±ΠΎΠ»ΡΠ½ΡΡ
. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΠΎΠ±Π° ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ° ΠΎΠ±Π»Π°Π΄Π°ΡΡ Π²ΡΡΠΎΠΊΠΎΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ (86,2 ΠΈ 87,2% ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ). Π ΡΠΎ Π²ΡΠ΅ΠΌΡ ΠΊΠ°ΠΊ ΠΌΠΈΠΊΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π°Π·ΠΈΡΡΠΎΠΌΠΈΡΠΈΠ½Π° Π±ΡΠ»Π° Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π²Ρ-ΡΠ΅ (Ρ 83,3%), ΡΠ΅ΠΌ ΡΠ΅ΡΠΈΠΊΡΠΈΠΌΠ° (58,3%) (p < 0,001), Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅, ΠΏΡΠΈ ΡΠ°Π»ΡΠΌΠΎΠ½Π΅Π»Π»Π΅Π·Π΅ ΠΎΠ½Π° ΡΠΎΡΡΠ°Π²ΠΈΠ»Π° 81,8%, Π° ΡΠ΅ΡΠΈΠΊΡΠΈΠΌΠ° Π»ΠΈΡΡ Ρ 52,6% Π±ΠΎΠ»ΡΠ½ΡΡ
. ΠΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠ΄ΠΈΠ»ΠΎ ΠΈ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΡΠΈΡ
Π°Π½ΡΠΈΠΌΠΈΠΊΡΠΎΠ±Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΠΠ Ρ Π΄Π΅ΡΠ΅ΠΉ.
ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΏΡΠΈΡ ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° Π±ΠΎΠ»ΡΠ½ΡΡ Π±ΡΠΎΠ½Ρ ΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π°ΡΡΠΌΠΎΠΉ Ρ Π°Π»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΠ΅ΠΉ
One hundred and eighteen bronchial asthma (BA) patients were examined by means of the Toronto alexithymie scale (TAS), and a brief version of the personality multilateral investigation method (PMIM), and the Spilberg-Khaninβs anxiety scale. Among them 55.1% of the patients were recognized as alexithymie persons. Asthmatic patients with alexithymia were reliably more neurotized compared with non-alexithymic ones. The revealed peculiarities of an actual personal condition of the alexithymie bronchial asthma patients cause a necessity of including methods of psychotherapeutic correction of alexithymia to a prevention measures system.ΠΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 118 Π±ΠΎΠ»ΡΠ½ΡΡ
Π±ΡΠΎΠ½Ρ
ΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π°ΡΡΠΌΠΎΠΉ (ΠΠ) Ρ ΠΏΠΎΠΌΠΎΡΡΡ Π’ΠΎΡΠΎΠ½ΡΡΠΊΠΎΠΉ Π°ΠΏΠ΅ΠΊΡΠΈΡΠΈΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠΊΠ°Π»Ρ (TAS), ΡΠΎΠΊΡΠ°ΡΠ΅Π½Π½ΠΎΠ³ΠΎ Π²Π°ΡΠΈΠ°Π½ΡΠ° ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ ΠΌΠ½ΠΎΠ³ΠΎΡΡΠΎΡΠΎΠ½Π½Π΅Π³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π»ΠΈΡΠ½ΠΎΡΡΠΈ (Π‘ΠΠΠ), ΡΠΊΠ°Π»Ρ ΡΡΠ΅Π²ΠΎΠ³ΠΈ Π‘ΠΏΠΈΠ»Π±Π΅ΡΠ³Π°-Π₯Π°Π½ΠΈΠ½Π°. ΠΠ»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΡΠ½ΡΠΌΠΈ ΠΏΡΠΈΠ·Π½Π°Π½Ρ 55,1% ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΠ. ΠΠΎΠ»ΡΠ½ΡΠ΅ ΠΠ Ρ Π°Π»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΠ΅ΠΉ ΠΈΠΌΠ΅Π»ΠΈ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΉ ΡΡΠΎΠ²Π΅Π½Ρ Π½Π΅Π²ΡΠΎΡΠΈΠ·Π°ΡΠΈΠΈ Π»ΠΈΡΠ½ΠΎΡΡΠΈ, ΡΠ΅ΠΌ Π½Π΅Π°Π»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΡΠ½ΡΠ΅ ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄Ρ. ΠΡΡΠ²Π»Π΅Π½Π½ΡΠ΅ Π½Π°ΠΌΠΈ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π»ΠΈΡΠ½ΠΎΡΡΠ½ΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π°Π»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΡΠ½ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
Π±ΡΠΎΠ½Ρ
ΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π°ΡΡΠΌΠΎΠΉ ΠΎΠ±ΡΡΠ»Π°Π²Π»ΠΈΠ²Π°ΡΡ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ Π² ΡΠΈΡΡΠ΅ΠΌΡ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΉ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΏΡΠΈΡ
ΠΎΡΠ΅ΡΠ°ΠΏΠ΅Π²ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΠΈ Π°Π»Π΅ΠΊΡΠΈΡΠΈΠΌΠΈΠΈ
Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists
It has now been demonstrated that the ΞΌ, Ξ΄(1), Ξ΄(2), and ΞΊ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R). Opioids are able to prevent necrosis and apoptosis of cardiomyocytes during I/R and improve cardiac contractility in the reperfusion period. The OR agonists exert an infarctβreducing effect with prophylactic administration and prevent reperfusionβinduced cardiomyocyte death when ischemic injury of heart has already occurred; that is, opioids can mimic preconditioning and postconditioning phenomena. Furthermore, opioids are also effective in preventing ischemiaβinduced arrhythmias
Respiratory syncytial viral infection in children. Role in the structure of respiratory pathology and clinical and immunological features
Acute respiratory infections (ARI) consistently occupy a leading place in the structure of infectious pathology, especially among children. The spectrum of pathogens is usually determined by the season and age aspect of the observed. In a large number of respiratory viruses, respiratory syncytial virus (RSV) occupies a special place due to the variety and severity of clinical manifestations of the disease caused by it in young children. This article is devoted to the analysis of the clinical course of RSV infection in children, the study of the features of the immune status against the background of this disease.It was found that in most cases of RSV infection in children was characterized by signs of bronchial obstruction syndrome and as a consequence in this group of children were found to have dysfunction of the immune system and reduction in the total number of T-lymphocytes, the hyperactivation In-cell component of adaptive immunity, manifested disimmunoglobulinemia (increase in the content of total IgE at lower IgA and IgG), that is, with the formation of immunodeficiency states from T- and B-cell links of adaptive immunity, with long-term recovery of impaired performance, even against the background of effective antiviral therapy
Independent work of students as an important stage in the preparation of medical students in bioorganic chemistry major in distance learning
Biochemistry is a basic discipline in the training of medical universitiesβ medical staff. The purpose of the study of this subject is to form studentsβ knowledge about metabolism as the basis of vital activity of the organism. The leading role in the study of biochemistry belongs to the independent work of students in class and out of class time. In the aim of rising the
competency-based approach in the teaching of biochemistry the priority for
students of medical students is not the possession of a large amount of information, but the ability to use it logically. In order to organise studentsβ independent work under distance learning
conditions, teachers of the department have developed educational and
methodological materials, including methodological guidelines for students,
presentations for better knowledge acquisition, tests and practical materials
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