Influence of seed pretreated in sodium chloride on the salt tolerance of cherry radish (Raphanus sativus L.).

This study was conducted to evaluate the effect of sodium chloride (NaCl) seed soaking on seed germination and plant growth of cherry radish (Raphanus sativus L.) under saline conditions. Seeds were pretreated by soaking in NaCl solutions at concentrations of 0, 1500, 3000 and 4500 ppm. The pretreated seeds were divided into two groups: the first group was germinated in Petri dishes, and the second group was sown in pots. Both groups were irrigated with different concentrations of salinity (tap water, 1000, 2000 and 3000 ppm NaCl). The results indicated that the salinity of the irrigation water decreased the seed germination percentage and leaf chlorophyll content under a salinity level of 3000 ppm. On the other hand, pretreatment of seeds with NaCl solution led to a gradual increase in germination percentage and total chlorophyll content of leaves. Pretreatment with 4500 ppm NaCl gave comparable values to the effect of control treatment under irrigation conditions with 1000 and 2000 ppm salinity. However, pretreatment of seeds with NaCl led to a gradual decrease in germination percentage, reaching 60% under a salinity level of 3000 ppm, and no obvious effect was seen on the leaf chlorophyll contents. Pretreatment of seeds by NaCl solutions increased the root and shoot fresh and dry weights, while shoot and root weight gradually decreased with the increasing salinity of irrigation water and regardless of the effects attributed to seed pretreatment. The increase in irrigation water salinity also led to a decrease in leaf area, and root length and root diameter, as well as root water contents. In contrast, the salinity led to a gradual increase in leaf specific weight, while the value of leaf number and leaf water contents were not affected. Therefore, the increased specific leaf weight as a result of the salinity of the irrigation water gave an indication that soaking the seeds in saline solutions increased the plant tolerance to salinity that lead to better plant growth

The prevalence of metabolic syndrome components, individually and in combination, in male patients admitted with acute coronary syndrome, without previous diagnosis of diabetes mellitus

Background: Mortality from cardiovascular disease in the Middle East is projected to increase substantially in the coming decades. The prevalence of metabolic syndrome (MS) in acute coronary syndrome (ACS) continues to raise interest, but data from the Middle East is limited, especially in non-diabetic patients. This study was conducted to ascertain the prevalence of MS and frequency of its components, individually and in combination, in a male population presenting with ACS, but without a previous diagnosis of diabetes mellitus (DM).Methods: This is a prospective study of 467 consecutive male patients hospitalized for ACS. They were categorized according to the specific criteria stated in the latest joint statement for the global definition of MS.Results: The mean age was (49.7910.7 years). Of the 467 patients, 324 (69.4%) fulfilled the criteria for MS. ST-Elevation Myocardial Infarction (STEMI) was identified in 178 patients (54.9%), and non-ST elevation ACS (NSTE-ACS) in 146 patients (45.1%). These proportions were not significantly different from those without MS (STEMI 51.7% vs. NSTE-ACS 48.3%, respectively). However, patients with MS were older (50.6910 vs. 47.9911 years; p0.012), and more than half of those with MS were above 50 years. The most common abnormal metabolic components were reduced high-density lipoprotein cholesterol (HDL-c; 94.1%), elevated fasting blood glucose (FBG; 89.8%), and elevated triglycerides (81.8%), followed by increased waist circumference (61.7%) and raised blood pressure (40.4%). The majority of patients with MS had three or more metabolic components (326 patients, 69.4%), and 102 (21.8%) had two components, but only 37 (8.4%) had a single component.Conclusions: In ACS patients, without previous history of DM, MS is highly prevalent. Reduced HDL, elevated FBG and triglycerides were the most frequent metabolic components. The majority had multiple components. These findings raise alarm and show that drug therapy alone may not be fully effective, unless the underlying risk factors causing MS, such as weight and exercise, are also tackled.Keywords: male; metabolic syndrome; acute coronary syndrome; diabetes mellitu

Over-expression of β-catenin is associated with high grade of prostatic cancer in Libyan patients

Objectives: At present, sufficient prognostic markers for prostate cancer (PCa) progression are still lacking, in spite of thorough investigation. The aim of this study was to evaluate abnormalities of β-catenin protein expression, subcellular localization and determine its relation to different clinicopathological features anddisease free survival in prostate cancer patients.Patients and methods: Forty prostate cancer specimens, obtained from patients with different stages of prostate cancer (83% stage IV) who underwent a radical prostatectomy or TURP flanked by 2006 and 2011, β-catenin was determined by immuno-histochemistry (IHC). The membranous expression was semi- quantitatively evaluated in four scores (0, 1+, 2+, 3+). Clinical records of these patients were studied for follow up data.Results: β-Catenin immune staining results show over-expression of β-catenin in PCa Libyan patients. There was no statistically significant difference in β-catenin immune expression as regards histopathological type, perineural invasion, tumor stage, biological recurrence. However, β-catenin over-expression showed significant correlation with old age (p < 0.014).Conclusions: We concluded that changes in expression and cell distribution of β-catenin correlated with the progression degree of prostate adenocarcinoma, signifying a role of this molecule as a marker of progression and prognosis. Further investigations, on a larger and more heterogeneous population, should be carried out to validate and extend our results.Keywords: Prostate cancer; β-Catenin expression; Immuno-histochemistry; Gleason score; Prognosi

A Unified Model of Internet Scale Alerting Services

In the last years, alerting systems have gained strengthened attention. Several systems have been implemented. For the evaluation and cooperation of these systems, the following problems arise: The systems and their models are not compatible, and existing models are only appropriate for a subset of conceivable application domains. Due to modeling differences, a simple integration of different alerting systems is impossible. What is needed, is a unified model that covers the whole variety of alerting service applications. This paper provides a unified model for alerting services that captures the special constraints of most application areas. The model can serve as a basis for an evaluation of alerting service implementations. In addition to the unified model, we define a general profile structure by which clients can specify their interest. This structure is independent of underlying profile definition languages. To eliminate drawbacks of the existing non-cooperating solitary services we introduce a new technique, the Mediating Alerting Service (MediAS). It establishes the cooperation of alerting services in an hierarchical and parallel way

Prov-Trust : towards a trustworthy SGX-based data provenance system

Data provenance refers to records of the inputs, entities, systems, and processes that influence data of interest, providing a historical record of the data and its origins. Secure data provenance is vital to ensure accountability, forensics investigation of security attacks and privacy preservation. In this paper, we propose Prov-Trust, a decentralized and auditable SGX-based data provenance system relying on highly distributed ledgers. This consensually shared and synchronized database allows anchored data to have public witness, providing tamper-proof provenance data, enabling the transparency of data accountability, and enhancing the secrecy and availability of the provenance data. Prov-Trust relies on Intel SGX enclave to ensure a trusted execution of the provenance kernel to collect, store and query provenance records. The use of SGX enclave protects data provenance and users’ credentials against malicious hosting and processing parties. Prov-Trust does not rely on a trusted third party to store provenance data while performing their verification using smart contracts and voting process. The storage of the provenance data in Prov-Trust is done using either the log events of Smart Contracts or blockchain’s transactions depending on the provenance change event, which enables low storage costs. Finally, Prov-Trust ensures an accurate privacy-preserving auditing process based on blockchain traces and achieved thanks to events’ logs that are signed by SGX enclaves, transactions being registered after each vote session, and sealing the linking information using encryption schemes

Electrochemical generation and utilization of alkoxy radicals

This highlight summarises electrochemical approaches for the generation and utilization of alkoxy radicals, predominantly focusing on recent advances (2012–present). The application of electrochemically generated alkoxy radicals in a diverse range of transformations is described, including discussion on reaction mechanisms, scope and limitations, in addition to highlighting future challenges in this burgeoning area of sustainable synthesis

Deconstructive functionalization of unstrained cycloalkanols via electrochemically generated aromatic radical cations

Herein we report an electrochemical approach for the deconstructive functionalization of cycloalkanols, where various alcohols, carboxylic acids, and N-heterocycles are employed as nucleophiles. The method has been demonstrated across a broad range of cycloalkanol substrates, including various ring sizes and substituents, to access useful remotely functionalized ketone products (36 examples). The method was demonstrated on a gram scale via single-pass continuous flow, which exhibited increased productivity in relation to the batch process

Cache coherence requirements for interprocess rendezvous

Multiprocessors in which a shared bus is used by the processor to communicate with common memory are an emerging class of machines where there is a need to support parallel programming languages. A language construct that is found in a number of parallel programming languages to support synchronization and communication in the interprocess rendezvous. Shared-bus multiprocessor require a protocol to keep the date in their caches coherent. There are two major categories of these protocols: invalidation and write-boadcast. This paper examines the requirements for cache coherence protocols to support efficient interprocessor rendezvous. The approach taken is to examine the memory referencing patterns to the run-time data structures during rendezvous execution. The appropriate coherence protocol is shown to be a function of the processor scheduling strategy used by the run-time system at synchronzation points during the rendezvous. When processes migrate freely as a result of the scheduling strategy, invalidation protocols are found to be more efficient. When migration is restricted by the scheduler, write-broadcast protocols are more efficient.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44571/1/10766_2005_Article_BF01407863.pd

Angiogenesis in urinary bladder carcinoma as defined by microvessel density (MVD) after immunohistochemical staining for Factor VIII and CD31

Background: Among the patients with bladder cancer, a group is still at risk of disease recurrence, progression, and death from their cancer after curative treatment. Angiogenesis is a crucial pathogenic mechanism for this type of urothelial carcinoma and is a potential therapeutic target. Objectives: To quantify tumor angiogenesis in bladder cancer and determine whether it correlates with tumor stage and grade. Patients and methods: A series of 42 archival samples from carcinomas of the urinary bladder were graded, staged, and analyzed for microvessel density (MVD) by a double immunohistochemical technique using Factor VIII (FVIII) and CD31 antibodies. The correlation between MVD and histopathological grade and tumor stage was evaluated. Results: FVIII and CD31 immunoreactivity was observed in 100% of cases and more intensely with CD31. Significantly higher MVD was determined in invasive tumors than in superficial tumors (p<0.05). MVD increased with tumor grade and stage (p<0.05); MVD was not affected by age or sex of the patients. Conclusion: These data demonstrate that MVD in bladder carcinoma correlates with the tumor grade and stage. Quantification of tumor angiogenesis may allow selection of the type of treatment for bladder cancer patients