Practical Strategies for Pharmacist Integration with Primary Care: A Workbook.

This workbook is a practical set of tips and resources to assist pharmacists in providing clinical pharmacy services to primary care providers and their patients. The content was written based on experiences in Vermont in 2014, however the topics should generalize to pharmacists in other areas

A Selected Ion Flow Tube Study of the Reactions of Several Cations with the Group 6B Hexafluorides SF6, SeF6, and TeF6

The first investigation of the ion chemistry of SeF$_6$ and TeF$_6$ is presented. Using a selected ion flow tube, the thermal rate coefficients and ion product distributions have been determined at 300 K for the reactions of fourteen atomic and molecular cations, namely H$_3$O$^+$, CF$_3^+$, CF$^+$, CF$_2^+$, H$_2$O$^+$, N$_2$O$^+$, O$^+$, CO$_2^+$, CO$^+$, N$^+$, N$_2^+$, Ar$^+$, F$^+$ and Ne$^+$ (in order of increasing recombination energy), with SeF$_6$ and TeF$_6$. The results are compared with those from the reactions of these ions with SF$_6$, for which the reactions with CF$^+$, CF$_2^+$, N$_2$O$^+$ and F$^+$ are reported for the first time. Several distinct processes are observed amongst the large number of reactions studied, including dissociative charge transfer, and F$^-$, F, F$_2^-$ and F$_2$ abstraction from the neutral reactant molecule to the reagent ion. The dissociative charge transfer channels are discussed in relation to vacuum ultraviolet photoelectron and threshold photoelectron-photoion coincidence spectra of XF$_6$ (X = S, Se, and Te). For reagent ions whose recombination energies lie between the first dissociative ionisation limit, XF$_6$ $\rightarrow$ XF$_5^+$ + F + e$^-$, and the onset of ionisation of the XF$_6$ molecule, the results suggest that if dissociative charge transfer occurs, it proceeds via an intimate encounter. For those reagent ions whose recombination energies are greater than the onset of ionisation, long-range electron transfer may occur depending on whether certain physical factors apply, for example non-zero Franck-Condon overlap. From the reaction kinetics, limits for the heats of formation of SeF$_4$, SeF$_5$, TeF$_4$ and TeF$_5$ at 298 K have been obtained; $\Delta_f$H$^o$(SeF$_4$) < -369 kJ mol$^{-1}$, $\Delta_f$H$^o$(SeF$_5$) < -621 kJ mol$^{-1}$, $\Delta_f$H$^o$(TeF$_4$) > -570 kJ mol$^{-1}$, and $\Delta_f$H$^o$(TeF$_5$) < -822 kJ mol$^{-1}$

Preliminary Test of Prescribed Burning for Control of Maple Leaf Cutter (Lepidoptera: Incurvariidae)

Leaf litter burning in the spring resulted in 87.5% mortality of maple leaf cutter pupae, Paraclemensia acerifoliella (Fitch). No apparent damage was observed on sugar maple or beech trees within the burn area

The effects of visual deprivation on adaptation to a rotating environment

Visual deprivation effects on adaptation to rotating environment - Motion sickness studie

The Woods-Saxon Potential in the Dirac Equation

The two-component approach to the one-dimensional Dirac equation is applied to the Woods-Saxon potential. The scattering and bound state solutions are derived and the conditions for a transmission resonance (when the transmission coefficient is unity) and supercriticality (when the particle bound state is at E=-m) are then derived. The square potential limit is discussed. The recent result that a finite-range symmetric potential barrier will have a transmission resonance of zero-momentum when the corresponding well supports a half-bound state at E=-m is demonstrated.Comment: 8 pages, 4 figures. Submitted to JPhys

Mission oriented study of advanced nuclear system parameters, phase 6. Volume 1 - Summary technical report Final report

Summarized study tasks, analyses, and results of advanced nuclear propulsion parameters for Mars and Venus mission

The Paraldor Project

Paraldor is an experiment in bringing the power of categorical languages to lattice QCD computations. Our target language is Aldor, which allows the capture of the mathematical structure of physics directly in the structure of the code using the concepts of categories, domains and their inter-relationships in a way which is not otherwise possible with current popular languages such as Fortran, C, C++ or Java. By writing high level physics code portably in Aldor, and implementing switchable machine dependent high performance back-ends in C or assembler, we gain all the power of categorical languages such as modularity, portability, readability and efficiency.Comment: 4 pages, 2 figures, Lattice 2002 conference proceeding

Direct interaction between EgFABP1, a fatty acid binding protein from echinococcus granulosus, and phospholipid membranes

&lt;p&gt;Background: Growth and maintenance of hydatid cysts produced by Echinococcus granulosus have a high requirement for host lipids for biosynthetic processes, membrane building and possibly cellular and developmental signalling. This requires a high degree of lipid trafficking facilitated by lipid transporter proteins. Members of the fatty acid binding protein (FABP) family have been identified in Echinococcus granulosus, one of which, EgFABP1 is expressed at the tegumental level in the protoscoleces, but it has also been described in both hydatid cyst fluid and secretions of protoscoleces. In spite of a considerable amount of structural and biophysical information on the FABPs in general, their specific functions remain mysterious.&lt;/p&gt; &lt;p&gt;Methodology/Principal Findings: We have investigated the way in which EgFABP1 may interact with membranes using a variety of fluorescence-based techniques and artificial small unilamellar vesicles. We first found that bacterial recombinant EgFABP1 is loaded with fatty acids from the synthesising bacteria, and that fatty acid binding increases its resistance to proteinases, possibly due to subtle conformational changes induced on EgFABP1. By manipulating the composition of lipid vesicles and the ionic environment, we found that EgFABP1 interacts with membranes in a direct contact, collisional, manner to exchange ligand, involving both ionic and hydrophobic interactions. Moreover, we observed that the protein can compete with cytochrome c for association with the surface of small unilamellar vesicles (SUVs).&lt;/p&gt; &lt;p&gt;Conclusions/Significance: This work constitutes a first approach to the understanding of protein-membrane interactions of EgFABP1. The results suggest that this protein may be actively involved in the exchange and transport of fatty acids between different membranes and cellular compartments within the parasite.&lt;/p&gt