27 research outputs found
Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes
Conservaci贸n de suelos en el sistema intercalado caf茅-frijol en la zona cafetera colombiana
Observatorio de Discapacidad de Colombia / The Colombian Observatory of Disability
Resumen
La Direcci贸n de Epidemiolog铆a y Demograf铆a (ded) y la Oficina de Promoci贸n Social del Ministerio de Salud y Protecci贸n Social (msps), dando cumplimiento a las competencias y obligaciones de seguimiento, evaluaci贸n y gesti贸n del conocimiento establecidas para el sector salud y desde el rol de esta cartera como rector del Sistema Nacional de Discapacidad (snd), ha priorizado el Observatorio de Discapacidad de Colombia como un instrumento t茅cnico para la formulaci贸n, desarrollo y evaluaci贸n de acciones de inclusi贸n social para la poblaci贸n con discapacidad en el marco del Sistema Nacional de la Discapacidad y el cumplimiento de la Convenci贸n sobre los Derechos de las Personas con Discapacidad. El prop贸sito de este art铆culo es describir la experiencia del Ministerio de Salud y Protecci贸n Social en la implementaci贸n del Observatorio de Discapacidad de Colombia, describiendo las actividades de planeaci贸n, mejoramiento y estructuraci贸n requeridas, as铆 como la recolecci贸n sistem谩tica, el an谩lisis e interpretaci贸n de datos e informaci贸n sobre la situaci贸n de discapacidad en el pa铆s. /
Abstract
The Direction of Epidemiology and Demography (ded) and the Social Promotion Office of the Ministry of Health and Social Protection, in compliance with the responsibilities and duties of monitoring, assessing and managing the knowledge in the health sector and as the Director of the National System of Disability (snd), has prioritized the Observatory of Disability of Colombia as a technical instrument for the formulation, development and assessment of the actions of social inclusion for people with disabilities within the framework of the National System of Disability and in compliance with the Convention on the Rights of people with Disabilities. The purpose of this article is to describe the experience of the Ministry of Health and Social Protection while implementing the Observatory of Disability of Colombia, describing the planning activities, the improvements and the required organization and also the systematic gathering, analysis and interpretation of data and information on the situation of disability in Colombia
Observatorio de Discapacidad de Colombia
The Direction of Epidemiology and Demography (ded) and the Social Promotion Office of the Ministry of Health and Social Protection, in compliance with the responsibilities and duties of monitoring, assessing and managing the knowledge in the health sector and as the Director of the National System of Disability (snd), has prioritized the Observatory of Disability of Colombia as a technical instrument for the formulation, development and assessment of the actions of social inclusion for people with disabilities within the framework of the National System of Disability and in compliance with the Convention on the Rights of people with Disabilities. The purpose of this article is to describe the experience of the Ministry of Health and Social Protection while implementing the Observatory of Disability of Colombia, describing the planning activities, the improvements and the required organization and also the systematic gathering, analysis and interpretation of data and information on the situation of disability in Colombia.聽La Direcci贸n de Epidemiolog铆a y Demograf铆a (DED) y la Oficina de Promoci贸n Social del Ministerio de Salud y Protecci贸n Social (msps), dando cumplimiento a las competencias y obligaciones de seguimiento, evaluaci贸n y gesti贸n del conocimiento establecidas para el sector salud y desde el rol de esta cartera como rector del Sistema Nacional de Discapacidad (SND), ha priorizado el Observatorio de Discapacidad de Colombia como un instrumento t茅cnico para la formulaci贸n, desarrollo y evaluaci贸n de acciones de inclusi贸n social para la poblaci贸n con discapacidad en el marco del Sistema Nacional de la Discapacidad y el cumplimiento de la Convenci贸n sobre los Derechos de las Personas con Discapacidad. El prop贸sito de este art铆culo es describir la experiencia del Ministerio de Salud y Protecci贸n Social en la implementaci贸n del Observatorio de Discapacidad de Colombia, describiendo las actividades de planeaci贸n, mejoramiento y estructuraci贸n requeridas, as铆 como la recolecci贸n sistem谩tica, el an谩lisis e interpretaci贸n de datos e informaci贸n sobre la situaci贸n de discapacidad en el pa铆s.
Reconstrucci贸n de experiencias y percepciones propias de j贸venes habitantes de calle
En este art铆culo describimos los resultados de la investigaci贸n realizada en la Casa de Acogida para j贸venes de Medell铆n, trabajo en el que buscamos dar cuenta de la autopercepci贸n de los individuos j贸venes en situaci贸n de calle que est谩n en una etapa de recuperaci贸n, en relaci贸n con la forma en que los perciben los otros. Para ello, implementamos una metodolog铆a de investigaci贸n de tipo cualitativa, orientada por un enfoque fenomenol贸gico que permitiera la reconstrucci贸n de sus experiencias. En el dise帽o metodol贸gico mezclamos t茅cnicas experienciales con la realizaci贸n de grupos focales, lo que nos permiti贸 el levantamiento de la informaci贸n. Entre los hallazgos presentamos las reflexiones que las personas j贸venes realizan sobre su proceso de resocializaci贸n, la estigmatizaci贸n y las iniciativas relacionadas con el cambio de vida
MLH1 and MSH2 mutations in Colombian families with hereditary nonpolyposis colorectal cancer (Lynch syndrome) - Description of four novel mutations
This study searched for mutations in the MLH1 and MSH2 genes in 23 unrelated Colombian families with suspected hereditary nonpolyposis colorectal cancer (HNPCC). The families were grouped according to the fulfillment of the Amsterdam II criteria or the Bethesda guidelines. We screened all probands by single-strand conformational polymorphism (SSCP) and direct DNA sequencing. Eleven families fulfilled the Amsterdam criteria II and 12 families the Bethesda guidelines. Germline mutations were detected in 11 families, which corresponds to a mutation detection rate of 48%. When only families fulfilling the Amsterdam II criteria were analyzed, the mutation detection rate rose to 82%. Only 8% of the mutation detection rate was found in families following the Bethesda guidelines. Three mutations were shared by two different families, which corresponds to a total of eight different mutations, seven of them found in the MLH1 gene and one in the MSH2 gene. We have identified four mutations that have not been previously reported to the International Collaborative Group of HNPCC. Three of these are pathogenic, a single base substitution (C > T) at codon 640, exon 17, a G deletion at codon 619, exon 16 and in the MLH1 gene and a two-nucleotide deletion (TG) at codon 184, exon 3 in the MSH2. Also, an unclassified variant, a substitution (C > G) at the codon 141, exon 5 of the MLH1, was detected. 漏 Springer 2005
Reconstrucci贸n de experiencias y percepciones propias de j贸venes habitantes de calle
This article describes the results of research carried out in the Medellin
Youth Reception House. The study explored the self-perception of homeless youth who are now in
the recovery phase, in terms of how they are perceived by others. A methodology of qualitative
investigation using a phenomenological approach was applied and facilitated the reconstruction of
their experiences. The information was gathered using a mix of experiential techniques and focus
groups. The results of the study include the subjects鈥檙eflections on their process of re-socialization,
stigmatization and initiatives related to how they changed their lives form. change of life are among
the findings in this studyNeste artigo se descrevem os resultados da pesquisa realizada no Abrigo
para jovens de Medell铆n, que procurou explicar a auto-percep莽茫o dos jovens moradores de rua que
est茫o em uma fase de recupera莽茫o, em rela莽茫o 脿 forma como eles s茫o percebidos pelos outros,
para o qual foi implementada uma metodologia de pesquisa qualitativa guiada por uma abordagem
fenomenol贸gica que permitiria a reconstru莽茫o das suas experi锚ncias. No desenho metodol贸gico foram
misturadas t茅cnicas experienciais com a realiza莽茫o de grupos focais que permitiram o levantamento
da informa莽茫o. Entre os resultados s茫o apresentadas as reflex玫es que os jovens fizeram sobre o seu
processo de ressocializa莽茫o, a estigmatiza莽茫o e as iniciativas relacionadas com a mudan莽a de vidaEn este art铆culo describimos los resultados de la investigaci贸n realizada en la Casa de Acogida para j贸venes de Medell铆n, trabajo en el que buscamos dar cuenta de la autopercepci贸n de los individuos j贸venes en situaci贸n de calle que est谩n en una etapa de recuperaci贸n, en relaci贸n con la forma en que los perciben los otros. Para ello, implementamos una metodolog铆a de investigaci贸n de tipo cualitativa, orientada por un enfoque fenomenol贸gico que permitiera la reconstrucci贸n de sus experiencias. En el dise帽o metodol贸gico mezclamos t茅cnicas experienciales con la realizaci贸n de grupos focales, lo que nos permiti贸 el levantamiento de la informaci贸n. Entre los hallazgos presentamos las reflexiones que las personas j贸venes realizan sobre su proceso de resocializaci贸n, la estigmatizaci贸n y las iniciativas relacionadas con el cambio de vida
MLH1 and MSH2 mutations in Colombian families with hereditary nonpolyposis colorectal cancer (Lynch syndrome) - Description of four novel mutations
This study searched for mutations in the MLH1 and MSH2 genes in 23 unrelated Colombian families with suspected hereditary nonpolyposis colorectal cancer (HNPCC). The families were grouped according to the fulfillment of the Amsterdam II criteria or the Bethesda guidelines. We screened all probands by single-strand conformational polymorphism (SSCP) and direct DNA sequencing. Eleven families fulfilled the Amsterdam criteria II and 12 families the Bethesda guidelines. Germline mutations were detected in 11 families, which corresponds to a mutation detection rate of 48%. When only families fulfilling the Amsterdam II criteria were analyzed, the mutation detection rate rose to 82%. Only 8% of the mutation detection rate was found in families following the Bethesda guidelines. Three mutations were shared by two different families, which corresponds to a total of eight different mutations, seven of them found in the MLH1 gene and one in the MSH2 gene. We have identified four mutations that have not been previously reported to the International Collaborative Group of HNPCC. Three of these are pathogenic, a single base substitution (C > T) at codon 640, exon 17, a G deletion at codon 619, exon 16 and in the MLH1 gene and a two-nucleotide deletion (TG) at codon 184, exon 3 in the MSH2. Also, an unclassified variant, a substitution (C > G) at the codon 141, exon 5 of the MLH1, was detected. 漏 Springer 2005