Complex matching of RDF datatype properties

Property mapping is a fundamental component of ontology matching, and yet there is little support that goes beyond the identification of single property matches. Real data often requires some degree of composition, trivially exemplified by the mapping of "first name" and "last name" to "full name" on one end, to complex matchings, such as parsing and pairing symbol/digit strings to SSN numbers, at the other end of the spectrum. In this paper, we propose a two-phase instance-based technique for complex datatype property matching. Phase 1 computes the Estimate Mutual Information matrix of the property values to (1) find simple, 1:1 matches, and (2) compute a list of possible complex matches. Phase 2 applies Genetic Programming to the much reduced search space of candidate matches to find complex matches. We conclude with experimental results that illustrate how the technique works. Furthermore, we show that the proposed technique greatly improves results over those obtained if the Estimate Mutual Information matrix or the Genetic Programming techniques were to be used independently. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-40285-2_18

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Early childhood tumours arise from transformed embryonic cells, which often carry large copy number alterations (CNA). However, it remains unclear how CNAs contribute to embryonic tumourigenesis due to a lack of suitable models. Here we employ female human embryonic stem cell (hESC) differentiation and single-cell transcriptome and epigenome analysis to assess the effects of chromosome 17q/1q gains, which are prevalent in the embryonal tumour neuroblastoma (NB). We show that CNAs impair the specification of trunk neural crest (NC) cells and their sympathoadrenal derivatives, the putative cells-of-origin of NB. This effect is exacerbated upon overexpression of MYCN, whose amplification co-occurs with CNAs in NB. Moreover, CNAs potentiate the pro-tumourigenic effects of MYCN and mutant NC cells resemble NB cells in tumours. These changes correlate with a stepwise aberration of developmental transcription factor networks. Together, our results sketch a mechanistic framework for the CNA-driven initiation of embryonal tumours

Assessment of morphological variability and chemical composition of some local pepper (Capsicum annuum L.) populations on the area of Kosovo

Seven local pepper populations (Capsicum annuum L.) from different geographical regions of Kosovo, were evaluated for morphological traits, chemical composition, and antioxidant contents using standard analytical techniques. All local peppers populations were characterized for different morphological traits from seedling emergence to crop maturity. The total genetic variation for plant height (PH) was 11.72 cm or expressed in relative values was 27.94 %. Average of leaf area (LA) per plant was 2308.38 cm2, while the lowest value for LA was 1136 cm2. Yield per plant ranged from 265 to 691 g plant-1. The   acidity level was ranging from 1.44 to 1.61 %, carbohydrates varied greatly from 4.21 to 6.07 %. Vitamin C (as ascorbic acid) content in fresh fruit ranged from 65.544 to 520.51 mg 100g-1 of fresh mass. Minerals were of reasonable levels with Fe (15.31 mg kg-1), Ca (216.71 mg kg-1), Na (406.01 mg kg-1), K (1851 mg kg-1), and Zn (5.74 mg kg-1).</p