2,304 research outputs found

    Morphological variation of the newly confirmed population of the javelin sand boa, Eryx jaculus (Linnaeus, 1758) (Serpentes, erycidae) in Sicily, Italy

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    The presence of the Javelin sand boa in Sicily has recently been confirmed. Here the morphological characters and sexual dimorphism of the Sicilian population of Eryx jaculus are presented. Seven meristic and six metric characters in 96 specimens from Sicily were examined. The results show that tail length, snout-vent length, the distance between nostrils and the number of ventral and subcaudal scales are different between sexes. The characters found in the Sicilian population of the Javelin sand boa resemble those of the African population (ssp. jaculus) rather than the Eurasian population (ssp. turcicus), but biomolecular studies are necessary to understand its taxonomic identity

    Observation of Fragile-to-Strong Dynamic Crossover in Protein Hydration Water

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    At low temperatures proteins exist in a glassy state, a state which has no conformational flexibility and shows no biological functions. In a hydrated protein, at and above 220 K, this flexibility is restored and the protein is able to sample more conformational sub-states, thus becomes biologically functional. This 'dynamical' transition of protein is believed to be triggered by its strong coupling with the hydration water, which also shows a similar dynamic transition. Here we demonstrate experimentally that this sudden switch in dynamic behavior of the hydration water on lysozyme occurs precisely at 220 K and can be described as a Fragile-to-Strong dynamic crossover (FSC). At FSC, the structure of hydration water makes a transition from predominantly high-density (more fluid state) to low-density (less fluid state) forms derived from existence of the second critical point at an elevated pressure.Comment: 6 pages (Latex), 4 figures (Postscript

    Psychiatric genetics and the structure of psychopathology

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    For over a century, psychiatric disorders have been defined by expert opinion and clinical observation. The modern DSM has relied on a consensus of experts to define categorical syndromes based on clusters of symptoms and signs, and, to some extent, external validators, such as longitudinal course and response to treatment. In the absence of an established etiology, psychiatry has struggled to validate these descriptive syndromes, and to define the boundaries between disorders and between normal and pathologic variation. Recent advances in genomic research, coupled with large-scale collaborative efforts like the Psychiatric Genomics Consortium, have identified hundreds of common and rare genetic variations that contribute to a range of neuropsychiatric disorders. At the same time, they have begun to address deeper questions about the structure and classification of mental disorders: To what extent do genetic findings support or challenge our clinical nosology? Are there genetic boundaries between psychiatric and neurologic illness? Do the data support a boundary between disorder and normal variation? Is it possible to envision a nosology based on genetically informed disease mechanisms? This review provides an overview of conceptual issues and genetic findings that bear on the relationships among and boundaries between psychiatric disorders and other conditions. We highlight implications for the evolving classification of psychopathology and the challenges for clinical translation

    Inscribed Greek Thunderstones as House- and Body-Amulets in Roman Imperial Times

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    La rĂ©utilisation des haches nĂ©olithiques (Ă©galement appelĂ©es « celts » ou « pierres de foudre ») comme des amulettes Ă  l’époque romaine est aujourd’hui sous-estimĂ©e. En consĂ©quence, la date ancienne des deux petits exemples inscrits du British Museum (BM nos 1* et 504) est maintenant remise en doute, en raison d’une Ă©valuation nĂ©gative qui dĂ©coule de l’utilisation insuffisante de comparanda. En comparaison avec le corpus croissant de pierres magiques, les mĂ©dias de ces deux petites haches (jadĂ©ite ou serpentine), leur poli et leur forme semblent en effet suspects et difficiles Ă  Ă©valuer comme gemmes en soi, mais quand on les compare Ă  d’autres haches nĂ©olithiques inscrites et anĂ©pigraphes trouvĂ©es dans sites romains et plus tard, il s’avĂšre que les deux pierres Ă  Londres appartiennent Ă  une catĂ©gorie bien dĂ©finie de « pierres de foudre » rĂ©utilisĂ©es comme amulettes.The re-use of Neolithic axe-heads (also known as “celts” or “thunderstones”) as amulets in Roman times is nowadays underappreciated. As a result, the ancient date of two small inscribed examples in the British Museum (BM nos. 1* and 504) is now in doubt,a negative assessment that arises from the use of insufficient comparanda. When compared with the growing corpus of magical gems, the media of these two small axe-heads (jadeite or serpentine), their high polish and their shape do indeed seem suspicious and difficult to assess as gems per se, but when viewed alongside other thunderstones, inscribed and uninscribed, found in Roman and later sites, we can see that both of the London stones belong to a clearly defined category of thunderstones reused as amulets

    First data on the repellent activity of essential oils of Citrus limon towards medfly (Ceratitis capitata)

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    The biological activity of peel essential oils of two Sicilian cultivars of C. limon, ‘Interdonato’ and ‘Lunario’, was investigated by electrophysiological recordings (EAG) and field trials on Ceratitis capitata (Wiedemann) (Diptera Tephritidae). The EAG data showed a remarkable dose-response relationship and a low activation threshold dose (10-3M) for both essential oil extracts. In field tests, essential oils showed a good repellent and antiovipositional activi- ty on ‘Navelina’ oranges, and in particular the essential oils of ‘Lunario’ pro- vided the same results of kaolin. Potential applications of essential oils from C. limon cultivars against C. capitata in organic farming are discussed
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