2,691 research outputs found

    POTENTIAL OF AGRICULTURAL DEVELOPMENT TO INCREASE RURAL EMPLOYMENT

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    The paper examined whether increasing agricultural output would lead to an expansion of employment in rural areas in the Caribbean and Sub-Saharan Africa (SSA). The paper found that the agricultural development problems in the Caribbean and SSA are very similar, especially, declining export demand for products, adverse trade policies and the actions of nature, causing damage to agricultural production. The simulations performed showed that in both regions, even a 4% annual increase in agricultural output has the potential for annually increasing agricultural employment by over 6%, even with an annual technical progress of 1.5% in the case of SSA and 2% in the case of the Caribbean. Expanding rural employment through expansion of agricultural output is therefore a definite opportunity in the two regions.Increasing rural employment, Rural Development, Agricultural Development in Caribbean and Sub-Saharan Africa, Agricultural and Food Policy, Community/Rural/Urban Development, Environmental Economics and Policy, Financial Economics, Labor and Human Capital, Marketing, Research Methods/ Statistical Methods,

    An Estimation of the Efficient Size of Sugarcane Enterprises for Farmers in Trinidad

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    This research paper provides an estimation of the efficient size of operation for sugarcane farmers in Trinidad. The estimates were based on a sample of two hundred and twenty-seven farmers selected from a cost of sugarcane production survey. To identify the efficient size of operation the ordinary least square estimation technique was used. The identification of the efficient size of operation allowed a test of the hypothesis that the minimum point on the long run average cost curve was significantly greater than the average enterprise size of six acres. The long run total cost curve was estimated and the cubic functional form provided the best fit based on both the adjusted R2 and the result from the Wald test. The results of the estimation process indicated that the optimal size was 32 acres of sugarcane and that 98% of the farmers operated at less than this size.Cost function, cost elasticity, efficient size, sugar-cane, Trinidad, Agribusiness, Farm Management, Research Methods/ Statistical Methods,

    Copper Mining and Environmental Costs in Dominica

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    A proposal from an international mining company to establish a copper mining operation in the Caribbean island of Dominica could be highly favourable, given the potential for financial benefits associated with such a project. On the downside, such projects are often associated with environmental damage. The area targeted for this copper mine was a rainforest in the north-eastern portion of Dominica occupying around 12 percent of the island’s total land area. A critical question is therefore whether copper mining could be a viable alternative to agrarian uses of the targeted area, if both financial and environmental costs are taken into consideration. A Contingent Valuation Survey of Dominicans and Visitors allowed for inclusion of non-market costs in the analysis. Cost-Benefit and sensitivity analyses were carried out to assess project feasibility. The results indicated that NPV was negative under conservative assumptions. NPV was sensitive to changes in the price of copper and the inclusion of environmental costs did affect the level of price increase required to make NPV positive.Copper mining, Dominica, environmental costs, sensitivity analysis, cost-benefit, Agribusiness, Environmental Economics and Policy, Financial Economics,

    Meaning in distress: Exploring religion, spirituality and mental health social work practice in Northern Ireland.

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    This empirical study explores if, and how, religion and spirituality are relevant subjects for those experiencing mental distress in Northern Ireland (NI) and how, if at all, the subject is engaged with in mental health social work practice. Although there is some controversy in United Kingdom based research regarding the apparent benefit of religion and spirituality within mental health, service user research and literature suggests its importance within recovery. Literature on religion, spirituality and social work practice suggests the need to examine the social and political processes which persist around this subject in social work practice (Henery, 2003; Wong and Vinsky, 2009). This examination is appropriate given the role of religion within the political conflict in NI, the impact of the conflict upon social work practice (Campbell et al, 2013), the high incidence of mental ill health in NI and the apparent role of religion and spirituality within mental distress. This study considers how mental health social workers may engage with this subject within their practice not only as an aspect of service users’ identity but also within post conflict Northern Ireland. The study methodology and design drew upon narrative theory and grounded theory. I interviewed twelve mental health service users and twelve mental health social workers, and half of the participants from each group also took part in a follow-up telephone interview. All of the participants were invited to bring an object which expressed what religion and spirituality meant to them. Analysis explored the views and experiences of mental health service users and social workers about religion and spirituality, within specific aspects of the wider social field. Service user and social worker participants’ accounts suggested that whilst the role of religion and spirituality within mental distress was recognised, its inclusion in mental health social work practice was marked with questions of legitimacy. Some of these questions were explicitly framed within the conflict, whilst others were less so. The study found that although religion was associated with politics, sectarianism and violence, its role, and that of spirituality, as an aspect of identity and meaning-making, appeared to be underdeveloped. Two key findings are of particular note. 10 Firstly that service user participants had their own ‘hierarchy’ of religious and spiritual expression, which on occasion appeared to result in their being critical of other service users’ expressions. Secondly, some service users preferred to keep their spirituality to themselves as a strategy of empowerment. In addition the study also found that service users viewed the mental health professional relationship as focusing upon medical aspects of their care, for example physical health and medication management, with no scope to explore religion, spirituality and mental distress. Thus questions of legitimacy focused around the notion of privacy and whether talking about religion and spirituality within the mental health service user and social worker relationship was too sensitive, given its association with sectarianism. Furthermore, mental health service users were concerned about how a disclosure of religion and / or spirituality within mental distress would be viewed by the mental health professional: would it be viewed as indicative of deteriorating mental health? Overall the study identified a significant gap between how service users draw upon spirituality and / or religion within mental distress, and the space given to this within mental health social work practice. This gap is due to a myriad of factors ranging from the social worker’s biography, to wider issues around how religion and spirituality are conceptualised in contemporary society. This study also highlights the continuing impact of the Northern Ireland conflict on frontline social work provision. There is a need for policymaking to acknowledge the ambivalence that exists around spirituality and religion in mental health social work practice due to the conflict and other relevant factors. Finally, support is needed for practitioners and service users to acknowledge this aspect of mental well-being in a manner that gives service users choice about its inclusion in their mental health care

    CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation

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    <p>Abstract</p> <p>Background</p> <p>CXCR4, the receptor for the chemokine stromal-derived factor 1 (SDF-1), has been shown to mediate many of the processes essential for cancer progression such as tumor cell proliferation, metastasis, and angiogenesis. To understand the role of CXCR4 in the biology of neuroblastoma, a disease that presents with wide spread metastases in over 50% of patients, we screened ten patient derived-neuroblastoma cell-lines for basal CXCR4 expression and sought to identify characteristics that correlate with tumor cell phenotype.</p> <p>Results</p> <p>All cell lines expressed <it>CXCR4 </it>mRNA at variable levels, that correlated well with three distinct classes of CXCR4 surface expression (low, moderate, or high) as defined by flow cytometry. Analysis of the kinetics of CXCR4 surface expression on moderate and high expressing cell lines showed a time-dependent down-regulation of the receptor that directly correlated with cell confluency, and was independent of SDF1. Cell lysates showed the presence of multiple CXCR4 isoforms with three major species of approximately 87, 67 and 55 kDa associating with high surface expression, and two distinct species of 45 and 38 kDa correlating with low to null surface expression. Western blot analysis of CXCR4 immunoprecipitates showed that the 87 and 67 kDa forms were ubiquitinated, while the others were not. Finally, treatment of cells with a proteasome inhibitor resulted in down regulation of CXCR4 surface expression.</p> <p>Conclusions</p> <p>Taken together, these data show that regulation of CXCR4 surface expression in neuroblastoma cells can occur independently of SDF-1 contribution arguing against an autocrine mechanism. Additionally these data suggest that post-translational modifications of CXCR4, in part through direct ubiquitination, can influence trafficking of CXCR4 to the surface of neuroblastoma cells in a ligand-independent manner.</p

    Customer views on service delivery in the Child Support Agency

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    This research was commissioned to investigate further a range of issues identified in the last CSA national client survey carried out in 1995. It is a qualitative study involving in-depth interviews with parents with care and absent parents. The research aimed to identify client satisfaction and dissatisfaction arising specifically from operational or staff activities. The main findings are: Absent parents and parents with care accepted the principle of dual responsibility. Parents with care valued the recognition of the father's responsibilities and regular payments of maintenance. Although absent parents tended to agree with the Agency's aims, some thought they had been incorrectly implemented. The Agency was seen as pursuing 'soft targets' and thought to be ineffective in obtaining maintenance from absent parents who refused to comply. Overall people were left with an impression of an impersonal system consisting of forms, letters and, increasingly, telephone calls. The Agency was seen as lacking even handedness in ensuring that all absent parents paid maintenance. Many parents were dissatisfied with their assessment as they felt it was too high and therefore inaccurate. None of the parents were able to explain fully how their assessment had been calculated and many wanted to know the details of the formula used. There were mixed views on the forms used in the assessment, some found them easy to complete, while for others it was more difficult, but few had tried to use the help notes provided. There was some objection to having to provide information on partners income and the failure to ask about debt. Contact with the Agency was a source of dissatisfaction. Some parents disliked the tone of letters from the CSA, and many complained about delays and not being kept informed of progress. Very few parents in the study had had face-to-face contact with the CSA, but many said it would be their preferred method of contact. Although there were no cases of the absent parent giving up work as a result of involvement with the CSA, some reported no longer working overtime or looking for promotion, as they believed any extra income would go in maintenance payments. For parents with care there was a greater incentive to take employment when maintenance replaced Income Support, but if it was not regularly received, they had to live on a reduced amount of benefit

    On Upper Bounds for Toroidal Mosaic Numbers

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    In this paper, we work to construct mosaic representations of knots on the torus, rather than in the plane. This consists of a particular choice of the ambient group, as well as different definitions of contiguous and suitably connected. We present conditions under which mosaic numbers might decrease by this projection, and present a tool to measure this reduction. We show that the order of edge identification in construction of the torus sometimes yields different resultant knots from a given mosaic when reversed. Additionally, in the Appendix we give the catalog of all 2 by 2 torus mosaics.Comment: 10 pages, 111 figure

    Effects of Climate Change on Pasture Production and Forage Quality

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    Why Study Climate Change and Pastures? Pastures cover more than 14 million hectares in the eastern half of the United States and support grazing animal and hay production while also contributing to the maintenance of overall environmental quality and ecosystem services. Climate change is likely to alter the function of these ecosystems. This manipulative field experiment evaluated the effect of warming and additional precipitation on forage production and quality. What Did We Do? We initiated a multi-factor climate change study, elevating air temperature (+3Âș C) and increasing growing season precipitation (+30% of long-term mean annual), in a central Kentucky pasture managed for hay production. Treatments began in May 2009 and have run continuously since. We measured the effects of warming and increased precipitation on pasture production, forage quality metrics, and for endophyte-infected tall fescue, ergot alkaloid concentrations. What Have We Learned? Effects of warming and increased precipitation on total yearly pasture production varied depending on the year of study; however, climate treatments never reduced production below that of the ambient control. Effects on forage quality metrics were relatively subtle. For endophyte-infected tall fescue, warming increased both ergovaline and ergovalinine concentrations (+40% of that in control ambient plots) throughout the study. These results indicate that central Kentucky pastures may be relatively resilient to future climate change; however, warming induced increases in ergot alkaloid concentrations in endophyte-infected tall fescue suggests that animal issues associated with fescue toxicosis are likely to be exacerbated under future climatic conditions. Future Plans We will continue this study for one more growing season and then destructively harvest it (in Fall 2013)
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