Marketing images and consumers' experiences in selling environments

In a well-functioning market, consumers exert choices not just in purchases of products but also in selections of locations to enjoy shopping. Scholarly research has demonstrated that retail atmospheres impact on shoppers’ pleasurable shopping experiences. Demonstrating the marketing concept in action, shoppers consistently respond to this empowerment by for example, spending more time shopping and spending more money in retail facilities that are perceived to offer a pleasanter atmosphere and experience. This research pivots round an in-depth qualitative study that evaluated the impact of a plasma screens and specific informational content on shopping centre user behaviour. A phenomenological study of the effects of the medium, and the way in which these systems influence behaviour, permitted a far deeper investigation of our sample group vis-àvis increased browsing time and the propensity to spend. A series of eight focus discussions were conducted with local user groups of varying age and gender. Key themes drawn from the group discussions using axial coding indicated that the influence created by the images varied with subjects and settings. The general consensus was that such ‘screens’ created a certain ambience that influenced the way our subjects felt about the selling environment under study. Moreover, for our sample groups, there was clearly a link between the screened images and modern expectations of a selling environment. The plasma screens provided added enjoyment to shoppers’ experiences, providing them with more information enabling more informed shopping choices. The research concludes with implications for strategic marketing, theory and practice

A hermeneutic inquiry into user-created personas in different Namibian locales

Persona is a tool broadly used in technology design to support communicational interactions between designers and users. Different Persona types and methods have evolved mostly in the Global North, and been partially deployed in the Global South every so often in its original User-Centred Design methodology. We postulate persona conceptualizations are expected to differ across cultures. We demonstrate this with an exploratory-case study on user-created persona co-designed with four Namibian ethnic groups: ovaHerero, Ovambo, ovaHimba and Khoisan. We follow a hermeneutic inquiry approach to discern cultural nuances from diverse human conducts. Findings reveal diverse self-representations whereby for each ethnic group results emerge in unalike fashions, viewpoints, recounts and storylines. This paper ultimately argues User-Created Persona as a potentially valid approach for pursuing cross-cultural depictions of personas that communicate cultural features and user experiences paramount to designing acceptable and gratifying technologies in dissimilar locales

The effect of distance on observed mortality, childhood pneumonia and vaccine efficacy in rural Gambia.

We investigated whether straight-line distance from residential compounds to healthcare facilities influenced mortality, the incidence of pneumonia and vaccine efficacy against pneumonia in rural Gambia. Clinical surveillance for pneumonia was conducted on 6938 children living in the catchment areas of the two largest healthcare facilities. Deaths were monitored by three-monthly home visits. Children living >5 km from the two largest healthcare facilities had a 2·78 [95% confidence interval (CI) 1·74-4·43] times higher risk of all-cause mortality compared to children living within 2 km of these facilities. The observed rate of clinical and radiological pneumonia was lower in children living >5 km from these facilities compared to those living within 2 km [rate ratios 0·65 (95% CI 0·57-0·73) and 0·74 (95% CI 0·55-0·98), respectively]. There was no association between distance and estimated pneumococcal vaccine efficacy. Geographical access to healthcare services is an important determinant of survival and pneumonia in children in rural Gambia

Interface modification of clay and graphene platelets reinforced epoxy nanocomposites: a comparative study

The interface between the matrix phase and dispersed phase of a composite plays a critical role in influencing its properties. However, the intricate mecha-nisms of interface are not fully understood, and polymer nanocomposites are no exception. This study compares the fabrication, morphology, and mechanical and thermal properties of epoxy nanocomposites tuned by clay layers (denoted as m-clay) and graphene platelets (denoted as m-GP). It was found that a chemical modification, layer expansion and dispersion of filler within the epoxy matrix resulted in an improved interface between the filler mate-rial and epoxy matrix. This was confirmed by Fourier transform infrared spectroscopy and transmission electron microscope. The enhanced interface led to improved mechanical properties (i.e. stiffness modulus, fracture toughness) and higher glass transition temperatures (Tg) compared with neat epoxy. At 4 wt% m-GP, the critical strain energy release rate G1c of neat epoxy improved by 240 % from 179.1 to 608.6 J/m2 and Tg increased from 93.7 to 106.4 �C. In contrast to m-clay, which at 4 wt%, only improved the G1c by 45 % and Tg by 7.1 %. The higher level of improvement offered by m-GP is attributed to the strong interaction of graphene sheets with epoxy because the covalent bonds between the carbon atoms of graphene sheets are much stronger than silicon-based clay

Interaction of a Rectangular Jet with a Flat-Plate Placed Parallel to the Flow

An experimental study is carried out addressing the flowfield and radiated noise from the interaction of a large aspect ratio rectangular jet with a flat plate placed parallel to but away from the direct path of the jet. Sound pressure level spectra exhibit an increase in the noise levels for both the 'reflected' and 'shielded' sides of the plate relative to the free-jet case. Detailed cross-sectional distributions of flowfield properties obtained by hot-wire anemometry are documented for a low subsonic condition. Corresponding mean Mach number distributions obtained by Pitot-probe surveys are presented for high subsonic conditions. In the latter flow regime and for certain relative locations of the plate, a flow resonance accompanied by audible tones is encountered. Under the resonant condition the jet cross-section experiences an 'axis-switching' and flow visualization indicates the presence of an organized 'vortex street'. The trends of the resonant frequency variation with flow parameters exhibit some similarities to, but also marked differences with, corresponding trends of the well-known edgetone phenomenon

Cancer event rate and mortality with thienopyridines: a systematic review and meta-analysis

Introduction Thienopyridines are a class of antiplatelet drugs widely used in cardiovascular disease prevention and treatment. A recent concern has come to light regarding the safety of thienopyridines because of the possible risk of malignancy. We therefore performed a systematic review and meta-analysis to evaluate the association between thienopyridine exposure and malignancy. Methods We searched the MEDLINE and EMBASE databases in March 2016 for studies that evaluated incident cancer and cancer mortality with and without exposure to thienopyridines. Relevant studies were identified, and data were extracted and analysed using random-effects meta-analysis. Results A total of nine studies (six randomised controlled trials and three cohort studies) that included 282,084 participants were included. The cancer event rate with clopidogrel and prasugrel was 3.25% and 1.58% respectively. When compared with standard aspirin or placebo, thienopyridines are not significantly associated with cancer mortality and event rate (odds ratio [OR] 1.12, 95% confidence interval [CI] 0.80–1.56, n = 3; and OR 0.92, 95% CI 0.52–1.64, n = 2, respectively. Further analyses examining clopidogrel showed no significant association with cancer event rate or malignancy-related death. When comparing prasugrel with clopidogrel, no significant association was noted for cancer event rate (OR 1.10, 95% CI 0.89–1.37, n = 2]. Subanalyses according to cancer location showed that thienopyridines are not significantly associated with malignancy mortality and/or incidence. Conclusions Our results suggest that there is currently insufficient evidence to suggest that thienopyridine exposure is associated with an increased risk of cancer event rate or mortality

Investigating the Feedback Path in a Jet-Surface Resonant Interaction

A resonant interaction between an 8:1 aspect ratio rectangular jet and flat-plates, placed parallel to the jet, is studied experimentally. For certain locations of the plate relative to the jet, the resonance takes place with a loud accompanying tone. The sound pressure level spectra are often marked by multiple peaks. The frequencies of the spectral peaks are studied as a function of the streamwise length of the plate, its relative location to the jet as well as the jet Mach number. It is demonstrated that the tones are not due to a simple feedback between the plate's trailing edge and the nozzle's exit; the leading edge of the plate also comes into play in the frequency selection. With parametric variation, it is found that there is an order in the most energetic spectral peaks; their frequencies cluster in distinct bands. The 'fundamental', i.e., the lowest frequency band is explained by an acoustic feedback involving diffraction at the plate's leading edge

Resonant Interaction of a Rectangular Jet with a Flat-Plate

A resonant interaction between a large aspect ratio rectangular jet and a flat-plate is addressed in this experimental study. The plate is placed parallel to but away from the direct path of the jet. At high subsonic conditions and for certain relative locations of the plate, the resonance accompanied by an audible tone is encountered. The trends of the tone frequency variation exhibit some similarities to, but also marked differences from, corresponding trends of the well-known edge-tone phenomenon. Under the resonant condition flow visualization indicates a periodic flapping motion of the jet column. Phase-averaged Mach number data obtained near the plate's trailing edge illustrate that the jet cross-section goes through large contortions within the period of the tone. Farther downstream a clear 'axis switching' takes place. These results suggest that the assumption of two-dimensionality should be viewed with caution in any analysis of the flow

Plasma inflammatory cytokines and survival of pancreatic cancer patients.

OBJECTIVES: Inflammation and inflammatory conditions have been associated with pancreatic cancer risk and progression in a number of clinical, epidemiological, and animal model studies. The goal of the present study is to identify plasma markers of inflammation associated with survival of pancreatic cancer patients, and assess their joint contribution to patient outcome. METHODS: We measured circulating levels of four established markers of inflammation (C-reactive protein (CRP), interleukin-6 (IL-6), soluble tumor necrosis factor receptor type II (sTNF-RII), and macrophage inhibitory cytokine-1 (MIC-1)) in 446 patients enrolled in an ongoing prospective clinic-based study. Hazard ratios (HRs) and 95% confidence intervals (CI) for death were estimated using multivariate Cox proportional hazards models. RESULTS: Overall mortality was significantly increased in patients in the top quartile of CRP (HR = 2.52, 95% CI: 1.82-3.49), IL-6 (HR = 2.78, 95% CI: 2.03-3.81), sTNF-RII (HR = 2.00, 95% CI: 1.46-2.72), and MIC-1 (HR = 2.53, 95% CI: 1.83-3.50), compared to those in the bottom quartile (P-trend CONCLUSION: Individual elevated plasma inflammatory cytokines are associated with significant and dramatic reductions in pancreatic cancer patient survival. Furthermore, we observed an independent combined effect of those cytokines on patient survival, suggesting that multiple inflammatory pathways are likely involved in PDAC progression. Future research efforts to target the inflammatory state using combination strategies in pancreatic cancer patients are warranted

Experimental and Computational Study of Tones Occurring with a Coaxial Nozzle

The source of audible tones occurring with a coaxial nozzle in a range of low Mach numbers is explored experimentally as well as computationally. The hardware is comprised of an inner and an outer nozzle, without a center-body, that are held together by a set of four struts. With increasing jet Mach number (M(sub j)), first a tone occurred at about 2550 Hz around M(sub j)=0.06. At higher values of M(sub j) a tone at 5200 Hz dominated the noise spectra. The corresponding nondimensional frequency, based on effective thickness of the inner nozzle lip and jet exit velocity, turned out to be about 0.2, a value characteristic of Karmann vortex shedding. Thus, vortex shedding from the inner nozzle lip could be linked to the tones. From a comparison of the acoustic wavelengths and the nozzle dimensions, it was inferred that the vortex shedding excited a one-quarter-wave resonance within the divergent section of either the inner nozzle or the outer nozzle. This led to the generation of the sharp tones