10,404 research outputs found
CD44 Staining of Cancer Stem-Like Cells Is Influenced by Down-Regulation of CD44 Variant Isoforms and Up-Regulation of the Standard CD44 Isoform in the Population of Cells That Have Undergone Epithelial-to-Mesenchymal Transition
PMCID: PMC3577706This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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Geographies of Production I: Relationality revisited and the ‘practice shift’ in economic geography
This report considers recent developments and ongoing debates around relational economic geography, and a growing body work that has focused on economic practices as a means to better understand production processes and economic development. In particular it examines the critical reaction to relational thinking within the sub-discipline, and the nature of the debate about the degree to which relational work is - and needs to be - regarded as distinct from more traditional approaches to economic geography. It then considers how relational economic geography has become inflected towards an epistemological and methodological focus on practice. It argues that this engagement with economic practices provides the basis to respond to some of the limitations identified with earlier work, and opens up fruitful new potential for theorizing the nature of agency in the space economy
The United States Chiropractic Workforce: An alternative or complement to primary care?
UnlabelledBackgroundIn the United States (US) a shortage of primary care physicians has become evident. Other health care providers such as chiropractors might help address some of the nation's primary care needs simply by being located in areas of lesser primary care resources. Therefore, the purpose of this study was to examine the distribution of the chiropractic workforce across the country and compare it to that of primary care physicians.MethodsWe used nationally representative data to estimate the per 100,000 capita supply of chiropractors and primary care physicians according to the 306 predefined Hospital Referral Regions. Multiple variable Poisson regression was used to examine the influence of population characteristics on the supply of both practitioner-types.ResultsAccording to these data, there are 74,623 US chiropractors and the per capita supply of chiropractors varies more than 10-fold across the nation. Chiropractors practice in areas with greater supply of primary care physicians (Pearson's correlation 0.17, p-value < 0.001) and appear to be more responsive to market conditions (i.e. more heavily influenced by population characteristics) in regards to practice location than primary care physicians.ConclusionThese findings suggest that chiropractors practice in areas of greater primary care physician supply. Therefore chiropractors may be functioning in more complementary roles to primary care as opposed to an alternative point of access
Tunneling decay of false vortices
We consider the decay of vortices trapped in the false vacuum of a theory of
scalar electrodynamics in 2+1 dimensions. The potential is inspired by models
with intermediate symmetry breaking to a metastable vacuum that completely
breaks a U(1) symmetry, while in the true vacuum the symmetry is unbroken. The
false vacuum is unstable through the formation of true vacuum bubbles; however,
the rate of decay can be extremely long. On the other hand, the false vacuum
can contain metastable vortex solutions. These vortices contain the true vacuum
inside in addition to a unit of magnetic flux and the appropriate topologically
nontrivial false vacuum outside. We numerically establish the existence of
vortex solutions which are classically stable; however, they can decay via
tunneling. In general terms, they tunnel to a configuration which is a large,
thin-walled vortex configuration that is now classically unstable to the
expansion of its radius. We compute an estimate for the tunneling amplitude in
the semi-classical approximation. We believe our analysis would be relevant to
superconducting thin films or superfluids.Comment: 27 pages, 9 figure
The Battle of the Bulge: Decay of the Thin, False Cosmic String
We consider the decay of cosmic strings that are trapped in the false vacuum
in a theory of scalar electrodynamics in 3+1 dimensions. We restrict our
analysis to the case of thin-walled cosmic strings which occur when large
magnetic flux trapped inside the string. Thus the string looks like a tube of
fixed radius, at which it is classically stable. The core of the string
contains magnetic flux in the true vacuum, while outside the string, separated
by a thin wall, is the false vacuum. The string decays by tunnelling to a
configuration which is represented by a bulge, where the region of true vacuum
within, is ostensibly enlarged. The bulge can be described as the meeting, of a
kink soliton anti-soliton pair, along the length of the string. It can be
described as a bulge appearing in the initial string, starting from the string
of small, classically stable radius, expanding to a fat string of large,
classically unstable (to expansion) radius and then returning back to the
string of small radius along its length. This configuration is the bounce point
of a corresponding O(2) symmetric instanton, which we can determine
numerically. Once the bulge appears it explodes in real time. The kink soliton
anti-soliton pair recede from each other along the length of the string with a
velocity that quickly approaches the speed of light, leaving behind a fat tube.
At the same time the radius of the fat tube that is being formed, expands
(transversely) as it is no longer classically stable, converting false vacuum
to the true vacuum with ever diluting magnetic field within. The rate of this
expansion is determined by the energy difference between the true vacuum and
the false vacuum. Our analysis could be applied to a network, of cosmic strings
formed in the very early universe or vortex lines in a superheated
superconductor.Comment: 13 pages, 4 figure
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