1,486 research outputs found

    Automated DNA Motif Discovery

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    Ensembl's human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal. The evolved motif suggests the presence of Thymine followed by one or more Adenines etc. early in transcripts indicate a non-protein coding gene. Keywords: pseudogene, short and microRNAs, non-coding transcripts, systems biology, machine learning, Bioinformatics, motif, regular expression, strongly typed genetic programming, context-free grammar.Comment: 12 pages, 2 figure

    Vlasov Simulations of Trapping and Inhomogeneity in Raman Scattering

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    We study stimulated Raman scattering (SRS) in laser-fusion conditions with the Eulerian Vlasov code ELVIS. Back SRS from homogeneous plasmas occurs in sub-picosecond bursts and far exceeds linear theory. Forward SRS and re-scatter of back SRS are also observed. The plasma wave frequency downshifts from the linear dispersion curve, and the electron distribution shows flattening. This is consistent with trapping and reduces the Landau damping. There is some acoustic (ωk\omega\propto k) activity and possibly electron acoustic scatter. Kinetic ions do not affect SRS for early times but suppress it later on. SRS from inhomogeneous plasmas exhibits a kinetic enhancement for long density scale lengths. More scattering results when the pump propagates to higher as opposed to lower density.Comment: 4 pages, 6 figures. Submitted to "Journal of Plasmas Physics" for the conference proceedings of the 19th International Conference on Numerical Simulation of Plasma

    Kinetic Enhancement of Raman Backscatter, and Electron Acoustic Thomson Scatter

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    1-D Eulerian Vlasov-Maxwell simulations are presented which show kinetic enhancement of stimulated Raman backscatter (SRBS) due to electron trapping in regimes of heavy linear Landau damping. The conventional Raman Langmuir wave is transformed into a set of beam acoustic modes [L. Yin et al., Phys. Rev. E 73, 025401 (2006)]. For the first time, a low phase velocity electron acoustic wave (EAW) is seen developing from the self-consistent Raman physics. Backscatter of the pump laser off the EAW fluctuations is reported and referred to as electron acoustic Thomson scatter. This light is similar in wavelength to, although much lower in amplitude than, the reflected light between the pump and SRBS wavelengths observed in single hot spot experiments, and previously interpreted as stimulated electron acoustic scatter [D. S. Montgomery et al., Phys. Rev. Lett. 87, 155001 (2001)]. The EAW is strongest well below the phase-matched frequency for electron acoustic scatter, and therefore the EAW is not produced by it. The beating of different beam acoustic modes is proposed as the EAW excitation mechanism, and is called beam acoustic decay. Supporting evidence for this process, including bispectral analysis, is presented. The linear electrostatic modes, found by projecting the numerical distribution function onto a Gauss-Hermite basis, include beam acoustic modes (some of which are unstable even without parametric coupling to light waves) and a strongly-damped EAW similar to the observed one. This linear EAW results from non-Maxwellian features in the electron distribution, rather than nonlinearity due to electron trapping.Comment: 15 pages, 16 figures, accepted in Physics of Plasmas (2006

    Deformation and rupture of armour grade steel under localised blast loading

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    A series of 30 blast experiments were conducted on monolithic steel panels of two armour grade steels. The two steels evaluated were a high hardness armour (HHA) and a rolled homogenous armour (RHA). Tests were conducted at two standoff distances using a fixed charge diameter. The charge weight was varied to produce specific magnitudes of blast loading and to isolate the rupture threshold of each material. The results indicated that the HHA steel, generally reserved for ballistic protection, outperformed a more ductile RHA steel in terms of both its deformation resistance and rupture threshold. Optical and scanning electron microscopy was utilised for fractographic analysis of the ruptured plates. The failure of the steels in this investigation was found to be initiated by slant shear fracture with little to no localised thinning. This is in contrast to the tensile instability and ductile tearing predicted by established theories of plate rupture for mild steels under blast loading. The deformation and rupture of the candidate steels was analysed for all experimental conditions and compared to current empirical models based on a non-dimensional impulse parameter. While deformation behaviour is well predicted, the blast rupture threshold of the armour grade steels is poorly captured by current empirical modelling approaches. The identified shear fracture mode leads to lower energy absorption capabilities of the material compared to more ductile tensile failure

    Fundamentals of interface phenomena in advanced bulk nanoscale materials

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    The review is devoted to a study of interface phenomena influencing advanced properties of nanoscale materials processed by means of severe plastic deformation, high-energy ball milling and their combinations. Interface phenomena include processes of interface defect structure relaxation from a highly nonequilibrium state to an equilibrium condition, grain boundary phase transformations and enhanced grain boundary and triple junction diffusivity. On the basis of an experimental investigation, a theoretical description of the key interfacial phenomena controlling the functional properties of advanced bulk nanoscale materials has been conducted. An interface defect structure investigation has been performed by TEM, high-resolution x-ray diffraction, atomic simulation and modeling. The problem of a transition from highly non-equilibrium state to an equilibrium one, which seems to be responsible for low thermostability of nanoscale materials, was studied. Also enhanced grain boundary diffusivity is addressed. Structure recovery and dislocation emission from grain boundaries in nanocrystalline materials have been investigated by analytical methods and modeling
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