20 research outputs found

    Magnetic anisotropies and its optical manipulation in epitaxial bismuth ferrite/ferromagnet heterostructure

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    © 2018 Elsevier B.V. Exchange-coupled BiFeO3/ferromagnet thin film heterostructures are promising for a fast and power efficient control of magnetization of the ferromagnetic layer. In the paper, the results of the study of magnetic properties of the epitaxial Fe2B/BiFeO3heterostructure on (0 0 1)-SrTiO3substrate with ferromagnetic resonance (FMR) spectroscopy are presented. The hierarchy of magnetic anisotropies that determine the angular variation of the resonance field in-plane and in-/out-of the plane of the system include the tetragonal four-fold and uniaxial terms for the Fe2B layer, uniaxial term for antiferromagnetic BiFeO3layer and the exchange coupling at the interface. We find out that the exchange bias direction can be switched by a strong enough applied magnetic field. Both the exchange bias and an in-plane FMR resonance field of the heterostructure are strongly affected by the illumination with λ = 405 nm light. An optical tunability of the exchange bias and ferromagnetic resonance fields of the heterostructure has been demonstrated

    The ER Stress/UPR axis in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

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    Cellular protein homeostasis in the lungs is constantly disrupted by recurrent exposure to various external and internal stressors, which may cause considerable protein secretion pressure on the endoplasmic reticulum (ER), resulting in the survival and differentiation of these cell types to meet the increased functional demands. Cells are able to induce a highly conserved adaptive mechanism, known as the unfolded protein response (UPR), to manage such stresses. UPR dysregulation and ER stress are involved in numerous human illnesses, such as metabolic syndrome, fibrotic diseases, and neurodegeneration, and cancer. Therefore, effective and specific compounds targeting the UPR pathway are being considered as potential therapies. This review focuses on the impact of both external and internal stressors on the ER in idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) and discusses the role of the UPR signaling pathway activation in the control of cellular damage and specifically highlights the potential involvement of non-coding RNAs in COPD. Summaries of pathogenic mechanisms associated with the ER stress/UPR axis contributing to IPF and COPD, and promising pharmacological intervention strategies, are also presented

    Magnetic anisotropies and its optical manipulation in epitaxial bismuth ferrite/ferromagnet heterostructure

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    © 2018 Elsevier B.V. Exchange-coupled BiFeO3/ferromagnet thin film heterostructures are promising for a fast and power efficient control of magnetization of the ferromagnetic layer. In the paper, the results of the study of magnetic properties of the epitaxial Fe2B/BiFeO3heterostructure on (0 0 1)-SrTiO3substrate with ferromagnetic resonance (FMR) spectroscopy are presented. The hierarchy of magnetic anisotropies that determine the angular variation of the resonance field in-plane and in-/out-of the plane of the system include the tetragonal four-fold and uniaxial terms for the Fe2B layer, uniaxial term for antiferromagnetic BiFeO3layer and the exchange coupling at the interface. We find out that the exchange bias direction can be switched by a strong enough applied magnetic field. Both the exchange bias and an in-plane FMR resonance field of the heterostructure are strongly affected by the illumination with λ = 405 nm light. An optical tunability of the exchange bias and ferromagnetic resonance fields of the heterostructure has been demonstrated
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