882 research outputs found

    Motivo do uso de suplementos nutricionais por praticantes de atividade física de Antônio Prado-RS

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    Objective: To verify the reason for the use of nutritional supplements among gym goers in Antônio Prado-RS. Cross-sectional study evaluating all 222 physical activity practitioners attending the five gyms in the city using nutritional supplements. Whey protein was the most used supplement (40.5%). The frequency of whey protein, maltodextrin, creatine, caffeine, BCAA and mass gainer was higher, while collagen and omega-3 was lower in those looking for hypertrophy. For weight loss, there was a higher use of whey protein, maltodextrin, caffeine and BCAA. For well-being, collagen use was higher than whey protein, creatine and BCAA. In conclusion, proteins were more commonly used between those looking for hypertrophy and weight loss, while collagen was related to well-being.Objetivo: Verificar o motivo de uso de suplementos nutricionais entre frequentadores de academias de Antônio Prado-RS. Estudo transversal incluindo 222 praticantes de atividade física frequentadores das 5 academias da cidade que utilizavam suplementos nutricionais. O whey protein foi o mais utilizado (40,5%). O uso de whey protein, maltodextrina, creatina, cafeína, BCAA e hipercalórico foi maior, enquanto colágeno e ômega-3 foi menor em quem busca hipertrofia. Para emagrecimento, houve maior uso de whey protein, maltodextrina, cafeína e BCAA. Para busca de saúde/bem-estar, foi maior o uso de colágeno e menor whey protein, creatina, BCAA. Em conclusão, proteínas foram mais utilizadas na busca por hipertrofia e emagrecimento, enquanto o colágeno foi relacionado a saúde/bem-estar

    In Vitro and Ex Vivo Hemodynamic Testing of an Innovative Occluder for Paravalvular Leak After Transcather Aortic Valve Implantation

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    This study aims at achieving a proof-of-concept for a novel device designed to occlude the orifices that may form between transcatheter valves and host tissues after TAVI. The device effect on the performance of a SAPIEN XT with a paravalvular gap was assessed into an in vitro and ex vivo pulse duplicator. The in vitro tests were performed complying with the standard international regulations, measuring the trasvalvular pressure and regurgitant volumes with and without the paravalvular gap, and with the occluder correctly positioned into the gap. In the second series of tests, the leakage reduction due to the presence of the occluder was assessed for the same setup, into a beating swine heart. The occluder implantation decreased the regurgitant fraction of about 50% for the in vitro assessment and 75% for the ex vivo test, under rest operating conditions. These results suggest that suitably designed occluders can lead to important benefit in the PVL treatment

    In vitro assessment of pacing as therapy for aortic regurgitation

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    Background and objective Clinical evaluation of pacing therapy in mitigating the aortic insufficiency after transchateter aortic valve implantation often gives contradictory outcomes. This study presents an in vitro investigation aimed at clarifying the effect of pacing on paravalvular leakage. Methods A series of in vitro tests reproducing the heart operating changes clinically obtained by pacing was carried out in a 26 mm Edwards Sapien XT prosthesis with mild paravalvular leakage. The effect of pacing on the regurgitant volumes per cycle and per minute was quantified, and the energy and power consumed by the left ventricle were calculated. Results Results indicate that though pacing results in some reduction in the total regurgitation per cycle, the volume of fluid regurgitating per minute increases substantially, causing overload of left ventricle. Conclusions Our tests indicate no effective haemodynamic benefit from pacing, suggesting a prudential clinical use of this therapy for the treatment of postoperative aortic regurgitation

    In vitro haemodynamic testing of Amplatzer plugs for paravalvular leak occlusion after Transcather Aortic Valve Implantation

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    Objective: We aimed to in-vitro test Amplatzer devices (Amplatzer Vascular Plug II and Amplatzer Vascular Plug III, SJM St. Paul, MN) in closing PVL generated by transcatheter balloon expandable aortic valve prosthesis in order to quantify the effective treatment of PVL. Background: Transcatheter aortic valve replacement (TAVI) procedures represent the treatment of choice for high risk patients. Despite evolving technologies paravalvular leak (PVL) is still a major unaddressed issue. This severe complication significantly impair long-term survival. Percutaneous treatment of this complication is usually performed with the implantation of not specifically designed and not approved vascular devices. Methods: A 23mm Sapien XT (Edwards Lifesciences, Irvine, CA) was implanted in a rubber aortic root and a semi-elliptical shape PVL was created. The vascular occluder devices were implanted in the PVL and hemodynamic performance was tested in a pulse duplicator according to international standard ISO 5840-3:2013. Different type of comparison tests together with high speed camera recording allowed us to define the global efficiency of the occluders and their interaction with the transcatheter prosthesis. Results: The results revealed that the use of vascular plugs was not per se sufficient to produce an effective or substantial reduction of PVL with a maximum efficiency inferior of 50%. Recorded video showed clearly that the vascular plug always interfered with the leaflet of the prosthetic valve. Conclusions: Current used devices do not guarantee effective treatment of PVL and may otherwise compromise the structural integrity of the prosthetic valve implanted. Specific designed devices are required

    THEORETICAL BASE TO ORGANIZATIONS OF THE CONCLUSION OF THE CONCLUSIONS IN NONMONOTONIC AMBIENCE ON BASE CONDITIONALLYHUNG VARIABLE

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    It is offered one of the approach to organizations of the notional thinking of the intellectual systems, connected with development theoretical base conclusion of the conclusions in free non monotonic problem-solving area on base conditionally hung variable

    In vitro assessment of pacing as therapy for aortic regurgitation

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    Background and objective: Clinical evaluation of pacing therapy in mitigating the aortic insufficiency after transchateter aortic valve implantation often gives contradictory outcomes. This study presents an in vitro investigation aimed at clarifying the effect of pacing on paravalvular leakage. / Methods: A series of in vitro tests reproducing the heart operating changes clinically obtained by pacing was carried out in a 26 mm Edwards Sapien XT prosthesis with mild paravalvular leakage. The effect of pacing on the regurgitant volumes per cycle and per minute was quantified, and the energy and power consumed by the left ventricle were calculated. / Results: Results indicate that though pacing results in some reduction in the total regurgitation per cycle, the volume of fluid regurgitating per minute increases substantially, causing overload of left ventricle. / Conclusions: Our tests indicate no effective haemodynamic benefit from pacing, suggesting a prudential clinical use of this therapy for the treatment of postoperative aortic regurgitation

    Understanding and recognition of the right ventricular function and dysfunction via a numerical study

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    The role played by the right ventricular (RV) dysfunction has long been underestimated in clinical practice. Recent findings are progressively confirming that when the RV efficiency deteriorates both the right and the left circulation is (significantly) affected, but studies dedicated to a detailed description of RV hemodynamic role still lack. In response to such a gap in knowledge, this work proposes a numerical model that for the first time evaluates the effect of isolated RV dysfunction on the whole circulation. Lumped parameter modelling was applied to represent the physio-pathological hemodynamics. Different grades of impairment were simulated for three dysfunctions i.e., systolic, diastolic, and combined systolic and diastolic. Hemodynamic alterations (i.e., of blood pressure, flow, global hemodynamic parameters), arising from the dysfunctions, are calculated and analysed. Results well accord with clinical observations, showing that RV dysfunction significantly affects both the pulmonary and systemic hemodynamics. Successful verification against in vivo data proved the clinical potentiality of the model i.e., the capability of identifying the degree of RV impairment for given hemodynamic conditions. This study aims at contributing to the improvement of RV dysfunction recognition and treatment, and to the development of tools for the clinical management of pathologies involving the right heart

    Ready Worker One? High-Res VR for the Home Office

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    Many employees prefer to work from home, yet struggle to squeeze their office into an already fully-utilized space. Virtual Reality (VR) seemingly offered a solution with its ability to transform even modest physical spaces into spacious, productive virtual offices, but hardware challenges---such as low resolution---have prevented this from becoming a reality. Now that hardware issues are being overcome, we are able to investigate the suitability of VR for daily work. To do so, we (1) studied the physical space that users typically dedicate to home offices and (2) conducted an exploratory study of users working in VR for one week. For (1) we used digital ethnography to study 430 self-published images of software developer workstations in the home, confirming that developers faced myriad space challenges. We used speculative design to re-envision these as VR workstations, eliminating many challenges. For (2) we asked 10 developers to work in their own home using VR for about two hours each day for four workdays, and then interviewed them. We found that working in VR improved focus and made mundane tasks more enjoyable. While some subjects reported issues---annoyances with the fit, weight, and umbilical cord of the headset---the vast majority of these issues seem to be addressable. Together, these studies show VR technology has the potential to address many key problems with home workstations, and, with continued improvements, may become an integral part of creating an effective workstation in the home

    Sunglint correction in airborne hyperspectral images over inland waters

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    This study assessed sunglint effects in airborne high spatial and high spectral resolution images acquired by the SpecTIR sensor under different view-illumination geometries over the Brazilian Ibitinga reservoir (Case II waters). These effects were corrected using the Goodman et al. (2008) and the Kutser et al. (2009) methods, and a variant that used the continuum removal technique to calculate the oxygen absorption band depth. The performance of each method to removing sunglint effects was evaluated by a quantitative analysis of pre- and post-sunglint correction reflectance values (residual reflectance images). Furthermore, the analysis was supported by inspection of the reflectance differences along transects placed over homogeneous masses of waters or over specific portions of the scenes affected and non-affected by sunglint. Results showed that the algorithm of Goodman et al. (2008) produced better results than the other two methods, as it approached to zero the amplitude of the reflectance values between homogenous water masses free and contaminated by sunglint. The Kutser et al. (2009) method had also good performance, except for the most contaminated sunglint portions of the scenes. When the continuum removal technique was incorporated to the Kutser et al. (2009) method, results varied with the scene and were more sensitive to atmospheric correction artifacts and instrumental signal-to-noise ratio
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