fine classification of complex motion pattern in fencing

Abstract The subject of this study was fencing and the object was to classify the fundamental motions of fencers by creating a library of movements. Based on this library, thus, the recognition of motions during a real fencing match can be made. Kinematic data were acquired by a motion capture system (Vicon). The automated algorithm that recognized motions is based on three steps: a Principal Component Analysis for data dimension reduction, an innovative wavelet-based analysis of signals and a feature extraction method. The algorithm was tested on high level fencing athletes and it was found to be robust with a 12% of misclassification rate. It gave a description of how atheletes move and showed that in real match athletes do not execute fundamental motions but they mix different techniques in order to surprise the opponent

José Morales Saravia Destierros y modernidades. Hölderlin y Landívar

En su artículo de 2007 titulado «¿Qué hacemos con los teóricos queno hacen teoría?»1, Dorian Espezúa Salmón, siguiendo una propuestade Pierre Bourdieu, divide a los teóricos y críticos literarios peruanos encuatro categorías: profetas, sacerdotes, laicos y magos. Los profetas sonaquellos que, aunque desconfían del discurso, son capaces de sostener suverdad. Son hombres del mundo que no temen pensar desde su realidadni pierden el tiempo persiguiendo modas epistemológicas extranjeras.Los sacerdotes, por su parte, solo pueden repetir lo que dicen los profetas.Son los difusores del dogma. En principio, nuestro medio académicoestaría lleno de este tipo de especialistas. Los laicos viven separados detoda organización o confesión religiosa. Defienden la independencia delhombre y pueden nutrirse de distintas posturas, nunca sometiéndose aun credo. Por último, los magos presentan una racionalidad alternativadesde un entorno alejado de la ciudad letrada. Son los profetas fuera delcírculo académico. En este medio, carente de profetas y donde la teoríaliteraria cada vez surge menos de la literatura, la publicación de Destierrosy modernidades (2015), nuevo libro de José Morales Saravia, resulta unaforma refrescante de práctica crítica. Este es un estudio sobre la obra dedos poetas, el alemán Friedrich Hölderlin (1770-1843) y el novohispanoRafael Landívar (1731-1793), que parte no de teorías culturales con dudososfundamentos, sino del conocimiento profundo de las obras estudiadasy de la familiaridad con la poesía desde una perspectiva humanística.En las siguientes líneas, quisiera ofrecer al lector algunos alcances sobre laestructura y el contenido de esta publicación

Relaxation processes in thiophene-based random copolymers

The relaxation dynamics of soluble polyalkylthiophenes obtained by the random copolymerisation of 3,4-dibutylthiophene and 3-butylthiophene monomers is investigated. In these systems, the effective conjugation length, the optical gap and the non-radiative decay rate are controlled by varying the content of disubstituted monomers, the steric hindrance of which induces a twisting angle between thiophene rings. Several indications are reported in favour of spectral diffusion of the photoexcitations. Migration processes mainly occur within a few tens of picoseconds

Ranger VII Flight Path and Its Determination from Tracking Data

Flight path and tracking study of Ranger VII LUNAR prob

Mortality for chronic-degenerative diseases in Tuscany: Ecological study comparing neighboring areas with substantial differences in environmental pollution

Objectives: Environmental pollution is associated with morbidity and mortality for chronic-degenerative diseases. Recent data points out a relationship between proximity to industrial plants and mortality due to neoplasms. The aim of this study has been to compare mortality due to chronic-degenerative diseases in the area of Tuscany (Bassa Val di Cecina), Italy, characterized by the presence of 2 neighboring municipalities similar in terms of size but with substantial differences in industrial activities: Rosignano (the site of chemical, energy production and waste processing industries) and Cecina (with no polluting activity). Material and Methods: Standardized mortality rates for the 2001–2010 decade were calculated; the data of the whole Tuscany was assumed as reference. Environmental levels of pollutants were obtained by databases of the Environmental Protection Agency of Tuscany Region (Agenzia Regionale per la Protezione Ambientale della Toscana – ARPAT). Maximum tolerated pollutant levels set by national laws were assumed as reference. Results: In the whole Bassa Val di Cecina, significantly elevated standardized mortality rates due to mesothelioma, ischemic heart diseases, cerebrovascular diseases and Alzheimer and other degenerative diseases of nervous system were observed. In the municipality of Rosignano, a significant excess of mortality for all these groups of diseases was confirmed. On the contrary, the municipality of Cecina showed only significantly higher mortality rates for ischemic heart diseases. Elevated levels of heavy metals in sea water and of particulate matter which contains particles of diameter ≤ 10 mm (PM10) and ozone in air were detected in Rosignano. Conclusions: This study shows an excess of mortality for chronic-degenerative diseases in the area with elevated concentration of polluting factories. Proximity to industrial plants seems to represent a risk factor for those diseases. Int J Occup Med Environ Health 2017;30(4):641–65

Adaptive filtering for removing nonstationary physiological noise from resting state fMRI BOLD signals

fMRI is used to investigate brain functional connectivity after removing nonneural components by General Linear Model (GLM) approach with a reference ventricle-derived signal as covariate. Ventricle signals are related to low-frequency modulations of cardiac and respiratory rhythms, which are nonstationary activities. Herein, we employed an adaptive filtering approach to improve removing physiological noise from BOLD signals. Comparisons between filtering approaches were performed by evaluating the amount of removed signal variance and the connectivity between homologous contralateral regions of interest (ROIs). The global connectivity between ROIs was estimated with a generalized correlation named RV coefficient. The mean ROI decrease of variance was -52% and -11%, for adaptive filtering and GLM, respectively. Adaptive filtering led to higher connectivity between grey matter ROIs than that obtained with GLM. Thus, adaptive filtering is a feasible method for removing the physiological noise in the low frequency band and to highlight resting state functional networks

Cell death and impairment of glucose-stimulated insulin secretion induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the beta-cell line INS-1E.

The aim of this research was to characterize 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity on the insulin-secreting beta-cell line INS-1E. A sharp decline of cell survival (below 20%) was observed after 1 h exposure to TCDD concentrations between 12.5 and 25 nM. Ultrastructurally, beta-cell death was characterized by extensive degranulation, appearance of autophagic vacuoles, and peripheral nuclear condensation. Cytotoxic concentrations of TCDD rapidly induced a dose-dependent increase in intracellular calcium concentration. Blocking calcium entry by EGTA significantly decreased TCDD cytotoxicity. TCDD was also able to rapidly induce mitochondrial depolarization. Interestingly, 1 h exposition of INS-1E cells to very low TCDD concentrations (0.05-1 nM) dramatically impaired glucose-stimulated but not KCl-stimulated insulin secretion. In conclusion, our results clearly show that TCDD exerts a direct beta-cell cytotoxic effect at concentrations of 15-25 nM, but also markedly impairs glucose-stimulated insulin secretion at concentrations 20 times lower than these. On the basis of this latter observation we suggest that pancreatic beta-cells could be considered a specific and sensitive target for dioxin toxicity

Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression

Genetic variants in SLC16A11 were recently reported to be associated with type 2 diabetes in Mexican and other Latin American populations. The diabetes risk haplotype had a frequency of 50% in Native Americans from Mexico but was rare in Europeans and Africans. In the current study, we analyzed SLC16A11 in 12,811 North American Indians and found that the diabetes risk haplotype, tagged by the rs75493593 A allele, was nominally associated with type 2 diabetes (P = 0.001, odds ratio 1.11). However, there was a strong interaction with BMI (P = 5.1 × 10(-7)) such that the diabetes association was stronger in leaner individuals. rs75493593 was also strongly associated with BMI in individuals with type 2 diabetes (P = 3.4 × 10(-15)) but not in individuals without diabetes (P = 0.77). Longitudinal analyses suggest that this is due, in part, to an association of the A allele with greater weight loss following diabetes onset (P = 0.02). Analyses of global gene expression data from adipose tissue, skeletal muscle, and whole blood provide evidence that rs75493593 is associated with expression of the nearby RNASEK gene, suggesting that RNASEK expression may mediate the effect of genotype on diabetes