5,779 research outputs found
A Study of the Relationship Between the Ideological Tendencies of United States Supreme Court Cases Affecting the Press, 1946-1974
Analysis of United States Supreme Court decision-making in cases affecting the press is important to communication law because many significant aspects of the court’s political behavior cannot be studied by reading the opinions of the court. The great volume of cases and range of issues simply preclude meaningful analysis except when subjected to the quantitative techniques of data processing and measurement. The hypotheses are: 1. Basic attitudes of Supreme Court justices contribute to their voting behavior. 2. Basic attitudes of Supreme Court justices in civil liberties cases. 3. Basic attitudes of Supreme Court justices toward press issues contribute to their voting behavior in press cases
Controlling Geometry and Flow Through Bacterial Bridges on Patterned Lubricant‐Infused Surfaces (pLIS)
Spatial control of bacteria and biofilms on surfaces is necessary to understand the biofilm formation and the social interactions between bacterial communities, which could provide useful hints to study the biofilm‐involved diseases. Here patterned lubricant‐infused surfaces (pLIS) are utilized to fabricate connective structures named “bacterial bridges” between bacterial colonies of Pseudomonas aeruginosa by a simple dewetting method. It is demonstrated that the bacteria attached to hydrophilic areas and bacteria precipitated on lubricant infused borders both contribute to the formation of bacterial bridges. The geometry and distribution of bridges can be controlled using predesigned superhydrophobic–hydrophilic patterns. It is demonstrated that bacterial bridges connecting bacteria colonies act as bio‐microfluidic channels and can transport liquids, nutrients, and antibacterial substances between neighboring bacteria clusters. Thus, bacterial bridges can be used to study formation, spreading, and development of bacterial colonies, and communication within and between isolated biofilms
Massive Supergravity and Deconstruction
We present a simple superfield Lagrangian for massive supergravity. It
comprises the minimal supergravity Lagrangian with interactions as well as mass
terms for the metric superfield and the chiral compensator. This is the natural
generalization of the Fierz-Pauli Lagrangian for massive gravity which
comprises mass terms for the metric and its trace. We show that the on-shell
bosonic and fermionic fields are degenerate and have the appropriate spins: 2,
3/2, 3/2 and 1. We then study this interacting Lagrangian using goldstone
superfields. We find that a chiral multiplet of goldstones gets a kinetic term
through mixing, just as the scalar goldstone does in the non-supersymmetric
case. This produces Planck scale (Mpl) interactions with matter and all the
discontinuities and unitarity bounds associated with massive gravity. In
particular, the scale of strong coupling is (Mpl m^4)^1/5, where m is the
multiplet's mass. Next, we consider applications of massive supergravity to
deconstruction. We estimate various quantum effects which generate non-local
operators in theory space. As an example, we show that the single massive
supergravity multiplet in a 2-site model can serve the function of an extra
dimension in anomaly mediation.Comment: 24 pages, 2 figures, some color. Typos fixed and refs added in v
H-Diplo Roundtable XVII, 27 on Richard Nixon and Europe. The Reshaping of the Postwar Atlantic World
A set of reviews of Luke A. Nichter\u27s Richard Nixon and Europe. The Reshaping of the Postwar Atlantic World, with a response from the author
Death, organ transplantation and medical practice
A series of papers in Philosophy, Ethics and Humanities in Medicine (PEHM) have recently disputed whether non-heart beating organ donors are alive and whether non-heart beating organ donation (NHBD) contravenes the dead donor rule. Several authors who argue that NHBD involves harvesting organs from live patients appeal to "strong irreversibility" (death beyond the reach of resuscitative efforts to restore life) as a necessary criterion that patients must meet before physicians can declare them to be dead. Sam Shemie, who defends our current practice of NHBD, holds that in fact physicians consider patients to be dead or not according to physician intention to resuscitate or not
Weight Gain, Obesity, and Psychotropic Prescribing
A majority of psychiatric medications are known to generate weight gain and ultimately obesity in some patients. There is much speculation about the prevalence of weight gain and the degree of weight gain during acute and longitudinal treatment with these agents. There is newer literature looking at the etiology of this weight gain and the potential treatments being used to alleviate this side effect. The authors undertook a comprehensive literature review in order to present epidemiology, etiology, and treatment options of weight gain associated with antipsychotics, mood stabilizers, and antidepressants
Biofilm Bridges Forming Structural Networks on Patterned Lubricant‐Infused Surfaces
Despite many decades of research, biofilm architecture and spreading mechanisms are still not clear because of the heterogenous 3D structure within biofilms. Here, patterned “slippery” lubricant‐infused porous surfaces are utilized to study biofilm structure of Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Staphylococcus aureus. It is found that bacteria are able to spread over bacteria‐repellent lubricant‐infused regions by using a mechanism, termed “biofilm bridges”. Here, it is demonstrated that bacteria use bridges to form interconnected networks between distant biofilm colonies. Detailed structure of bridges shows a spatial distribution of bacteria with an accumulation of respiratory active bacteria and biomass in the bridges. The core–shell structure of bridges formed by two‐species mixed population is illustrated. It is demonstrated that eDNA and nutrients have a strong effect on biofilm bridges formation. Thus, it is believed that biofilm bridging is important to reveal the structure and communication within biofilms
Condensation of Excitons in Cu2O at Ultracold Temperatures: Experiment and Theory
We present experiments on the luminescence of excitons confined in a
potential trap at milli-Kelvin bath temperatures under cw-excitation. They
reveal several distinct features like a kink in the dependence of the total
integrated luminescence intensity on excitation laser power and a bimodal
distribution of the spatially resolved luminescence. Furthermore, we discuss
the present state of the theoretical description of Bose-Einstein condensation
of excitons with respect to signatures of a condensate in the luminescence. The
comparison of the experimental data with theoretical results with respect to
the spatially resolved as well as the integrated luminescence intensity shows
the necessity of taking into account a Bose-Einstein condensed excitonic phase
in order to understand the behaviour of the trapped excitons.Comment: 41 pages, 23 figure
Interactions between physical exercise, associative memory, and genetic risk for Alzheimer's disease.
The ε4 allele of the APOE gene heightens the risk of late onset Alzheimer's disease. ε4 carriers, may exhibit cognitive and neural changes early on. Given the known memory-enhancing effects of physical exercise, particularly through hippocampal plasticity via endocannabinoid signaling, here we aimed to test whether a single session of physical exercise may benefit memory and underlying neurophysiological processes in young ε3 carriers (ε3/ε4 heterozygotes, risk group) compared with a matched control group (homozygotes for ε3). Participants underwent fMRI while learning picture sequences, followed by cycling or rest before a memory test. Blood samples measured endocannabinoid levels. At the behavioral level, the risk group exhibited poorer associative memory performance, regardless of the exercising condition. At the brain level, the risk group showed increased medial temporal lobe activity during memory retrieval irrespective of exercise (suggesting neural compensatory effects even at baseline), whereas, in the control group, such increase was only detectable after physical exercise. Critically, an exercise-related endocannabinoid increase correlated with task-related hippocampal activation in the control group only. In conclusion, healthy young individuals carrying the ε4 allele may present suboptimal associative memory performance (when compared with homozygote ε3 carriers), together with reduced plasticity (and functional over-compensation) within medial temporal structures
Droplet‐Microarray: Miniaturized Platform for High‐Throughput Screening of Antimicrobial Compounds
Currently, there are no time-saving and cost-effective high-throughput screening methods for the evaluation of bacterial drug-resistance. In this study, a droplet microarray (DMA) system is established as a miniaturized platform for high-throughput screening of antibacterial compounds using the emerging, opportunistic human pathogen Pseudomonas aeruginosa (P. aeruginosa) as a target. Based on the differences in wettability of DMA slides, a rapid method for generating microarrays of nanoliter-sized droplets containing bacteria is developed. The bacterial growth in droplets is evaluated using fluorescence. The new method enables immediate screening with libraries of antibiotics. A novel simple colorimetric readout method compatible with the nanoliter size of the droplets is established. Furthermore, the drug-resistance of P. aeruginosa 49, a multi-resistant strain from an environmental isolate, is investigated. This study demonstrates the potential of the DMA platform for the rapid formation of microarrays of bacteria for high-throughput drug screening
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