616 research outputs found

    Mathematical circus clown tricks

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    The Mathematical Circus project was created in 2011 by the LUDUS association with the main goal of promoting the interest and motivation for learning mathematics. The Mathematical Circus team performs mathematical magic shows where complementary skills are merged to produce a high intervention capacity within a wide geographical range in Portugal. Some tricks are performed by a mathematical clown, a unique character in the circus world, who brings together the usual foolish characteristics of a clown and the rigorous mathematical knowledge. In this paper we will describe and explain some of the tricks of the Mathematical Circus repertoire involving the clown.info:eu-repo/semantics/publishedVersio

    Lyapunov Control on Quantum Open System in Decoherence-free Subspaces

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    A scheme to drive and manipulate a finite-dimensional quantum system in the decoherence-free subspaces(DFS) by Lyapunov control is proposed. Control fields are established by Lyapunov function. This proposal can drive the open quantum system into the DFS and manipulate it to any desired eigenstate of the free Hamiltonian. An example which consists of a four-level system with three long-lived states driven by two lasers is presented to exemplify the scheme. We have performed numerical simulations for the dynamics of the four-level system, which show that the scheme works good.Comment: 5 pages, 6 figure

    Optical mapping of neuronal activity during seizures in zebrafish

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    Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs. Recently, zebrafish has become an important model for studying epilepsy both in basic research and in drug discovery. Here, we employed a transgenic line with pan-neuronal expression of the genetically-encoded calcium indicator GCaMP6s to measure neuronal activity in zebrafish larvae during seizures induced by pentylenetretrazole (PTZ). With this approach, we mapped neuronal activity in different areas of the larval brain, demonstrating the high sensitivity of this method to different levels of alteration, as induced by increasing PTZ concentrations, and the rescuing effect of an anti-epileptic drug. We also present simultaneous measurements of brain and locomotor activity, as well as a high-throughput assay, demonstrating that GCaMP measurements can complement behavioural assays for the detection of subclinical epileptic seizures, thus enabling future investigations on human hypomorphic mutations and more effective drug screening methods. Notably, the methodology described here can be easily applied to the study of many human neuropathologies modelled in zebrafish, allowing a simple and yet detailed investigation of brain activity alterations associated with the pathological phenotype

    Evaluation de la stratĂ©gie d’élimination de la rougeole 2011-2015

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    La stratĂ©gie d’élimination de la rougeole 2011-2015 Ă©laborĂ©e et mise en oeuvre par l’OFSP a Ă©tĂ© Ă©valuĂ©e en utilisant diverses approches mĂ©thodologiques complĂ©mentaires. Les principaux rĂ©sultats montrent qu’un large consensus sur la stratĂ©gie a Ă©tĂ© obtenu sous l’impulsion de l’OFSP et que tous les cantons ont mis en oeuvre des mesures visant Ă  augmenter la couverture vaccinale. Une augmentation de la couverture vaccinale, du rattrapage vaccinal et une rĂ©duction des disparitĂ©s cantonales de couverture vaccinale ont Ă©tĂ© observĂ©es. Cependant l’objectif stratĂ©gique de couverture vaccinale 2 doses Ă  l’ñge de 2 ans n’a pas Ă©tĂ© obtenu dans tous les cantons pour lesquels on dispose d’une mesure en 2014-2015. Il est probable que la stratĂ©gie n’a pas encore dĂ©ployĂ© tous ses effets. Les mesures mises en oeuvre pour prĂ©venir et contenir les flambĂ©es Ă©pidĂ©miques et qui visent Ă  augmenter la couverture vaccinale devraient ĂȘtre poursuivies

    Feedback control of spin systems

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    The feedback stabilization problem for ensembles of coupled spin 1/2 systems is discussed from a control theoretic perspective. The noninvasive nature of the bulk measurement allows for a fully unitary and deterministic closed loop. The Lyapunov-based feedback design presented does not require spins that are selectively addressable. With this method, it is possible to obtain control inputs also for difficult tasks, like suppressing undesired couplings in identical spin systems.Comment: 16 pages, 15 figure
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