Understanding the Relationship between Food Variety, Food Intake, and Energy Balance

Purpose of Review: In accordance with US dietary guidance, incorporating variety into the diet can align with energy balance, though greater food variety in some categories may make energy balance more challenging. Thus, experimental and epidemiologic evidence is summarized on the relationship between food variety, food and energy intake, and energy balance. Recent Findings: Lab-based, experimental research consistently demonstrates that greater variety within foods or sensory characteristics of food increases food and energy intake within an eating occasion. Epidemiologic evidence is less consistent, potentially driven by differing methodologies, particularly in defining and measuring food variety. Moreover, the effect of variety on energy balance appears to be moderated by food energy density. Summary Integrating insights from experimental and epidemiologic research are essential for strengthening food variety guidance including developing evidence-based definitions of food variety, understanding moderators of the relationship, and developing practical guidance interpretable to consumers

Sustainable use of light for chemical and electrical energy production

The Earth receives around 1.9 x 106 EJ of energy in visible light each year but only a fraction of this sunlight energy is being converted to biomass (chemical energy) through the process of photosynthesis. There is no doubt our fossil fuel resources are depleting; therefore there is an urgent need for an alternative source of renewable energy that is sustainable. This project works on the potential of developing a novel cultivation system for maximising the use of solar energy by combining solar panels with outdoor microalgae ponds for the production of both chemical and electrical energy

Applications of Clustering with Mixed Type Data in Life Insurance

Death benefits are generally the largest cash flow item that affects financial statements of life insurers where some still do not have a systematic process to track and monitor death claims experience. In this article, we explore data clustering to examine and understand how actual death claims differ from expected, an early stage of developing a monitoring system crucial for risk management. We extend the $k$-prototypes clustering algorithm to draw inference from a life insurance dataset using only the insured's characteristics and policy information without regard to known mortality. This clustering has the feature to efficiently handle categorical, numerical, and spatial attributes. Using gap statistics, the optimal clusters obtained from the algorithm are then used to compare actual to expected death claims experience of the life insurance portfolio. Our empirical data contains observations, during 2014, of approximately 1.14 million policies with a total insured amount of over 650 billion dollars. For this portfolio, the algorithm produced three natural clusters, with each cluster having a lower actual to expected death claims but with differing variability. The analytical results provide management a process to identify policyholders' attributes that dominate significant mortality deviations, and thereby enhance decision making for taking necessary actions.Comment: 25 pages, 6 figures, 5 table

Effects of different light spectra on the growth, productivity and photosynthesis of two acclimated strains of Nannochloropsis sp.

Light (quantity and quality) is the main growth-limiting factor of photoautotrophic microalgae. The integration of selective permeable photovoltaic filters above microalgae cultivation systems has been proposed previously to improve both production efficiencies and economics. In order to optimize such system, we evaluated the growth and photosynthesis of two spectrally acclimated strains of Nannochloropsis sp. (MUR 266 and MUR 267) grown semi-continuously under different light spectra in this study. No significant differences in biomass productivity were observed between cultures acclimated under full blue (BL, 400-525 nm) and narrow blue (LEDB, 430-490 nm) light when compared to the positive control of white light (WL, 400-700 nm), while lower values were recorded under red (RL, 600-700 nm) and pink light (PL, 400-525, 600-700 nm) for both species. When compared to WL, the photosynthetic performance (Fq′/Fm′, αETR, ETRmax) of both species was higher under both BL and LEDB except for the Fq′/Fm′ of MUR 267 under LEDB. Chlorophyll a content was highest in cultures acclimated to RL while values tended higher under LEDB, RL and PL for MUR 267. Total lipid yield of both MUR 266 and MUR 267 was higher under BL and PL than WL. Based on the results of this study, theoretical modelling of the proposed photovoltaic-microalgae system indicate approximately 150-210 W m−2 of electricity could be potentially generated if only blue wavelengths (BL and LEDB) are selectively filtered from sunlight while converting the remaining unused spectrum of sunlight into electricity

Association between objectively measured physical activity and opioid, hypnotic, or anticholinergic medication use in older people – data from the Physical Activity Cohort Scotland study

Background: Centrally acting medications cause cognitive slowing and incoordination, which could reduce older people’s physical activity levels. This association has not been studied previously.Objectives: To examine the association between opioid, hypnotic and anticholinergic medication, and objectively measured physical activity, in a cohort of older people.Methods: We used data from the Physical Activity Cohort Scotland, a representative cohort of community-dwelling older people aged 65 and over who were assessed at baseline and again 2-3 years later. Objective physical activity was measured using Stayhealthy RT3 accelerometers over 7 days. Baseline medication use (opioid use, hypnotic use, modified anticholinergic risk score [mARS]) was obtained from linked, routinely collected community prescribing records. Cross-sectional and longitudinal associations between baseline medication use and both baseline activity and change in activity over time were analysed using unadjusted and adjusted linear regression models.Results: 310 participants were included in the analysis; mean age 77 (SD 7) years. No association was seen between baseline use of any medication class and baseline physical activity levels in unadjusted or adjusted models. For change in activity over time, there was no difference between users and non-users of hypnotics or opioids. Higher anticholinergic burden was associated with a steeper decline in activity over the follow up period (mARS=0: -7051 counts/24h/yr; mARS=1-2 -15942 counts/24h/yr; mARS>=3 -19544 counts/24h/yr; p=0.03) and this remained robust to multiple adjustments.Conclusion: Anticholinergic burden is associated with greater decline in objectively measured physical activity over time in older people, a finding not seen with hypnotic or opioid use

Menu labelling and food choice in obese adults: a feasibility study.

BACKGROUND: To date research examining the benefits of menu labelling in the UK is sparse. The aim of the present study was to examine the impact of menu labelling in a UK obese population. METHODS: Using a repeated measures design, 61 patients at a tier 3 weight management service completed four questionnaires to assess their food choice (control) and behaviour change when presented with 3 menu labelling formats (calorie content; nutrient content; and energy expenditure). RESULTS: All three forms of labelling increased participants weight control concerns compared to the control condition. There was a significant difference in content of food ordered in the three menu labelling formats compared to the control condition. The calorie condition had the largest percentage decrease in calories selected followed by energy expenditure and nutrient content. However, no difference was observed between the three conditions in the desire for menu labelling in restaurants to be introduced in the UK. CONCLUSIONS: The findings suggest that menu labelling should be enforced in the UK as it is both beneficial to promoting healthy eating and in demand. This study is the first to examine menu labelling in a UK obese population using energy expenditure equivalents to provide nutritional information

Application of poly(2-hydroxyethyl methacrylate) hydrogel disks for the immobilization of three different microalgal species

BACKGROUND: Algal growth on solid surfaces confers the advantage of combining the algal harvesting and bioprocessing steps at a single stage, in addition to the easier handling of the immobilized cells that occupy a reduced amount of space. The current work employed the application of macroporous poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogel disks as a water-insoluble, non-toxic and recyclable immobilization matrix for different microalgal strains (Nannochloropsis sp., Dunaliella salina, and Botryococcus braunii) that offer value-added products for various commercial applications. RESULTS: The study demonstrated the effect of variations in the surface characteristics of the algal strains and hydrogel surfaces on the immobilization efficiencies. Gelatin was further used to modify PHEMA hydrogels to achieve higher bioaffinity and surface hydrophilicity. The results showed that highly salt-tolerant microalgal cells (Dunaliella salina, Nannochloropsis sp.) had significantly higher tendencies to attach on the gelatin-modified PHEMA hydrogel compared with the freshwater B. braunii colonies; embedded within an extracellular matrix mainly made of hydrophobic components, which displayed better attachment to the unmodified PHEMA hydrogels. CONCLUSION: The proposed PHEMA hydrogels are easily-manufactured and highly durable materials with the hydrogel disks still retaining their integrity after several years when in contact with a liquid. PHEMA disks also have the benefits of having adjustable porosities by changing the composition of the polymerization mixture, and modifiable surface properties by simply binding various synthetic or natural molecules on their surfaces, which can bring several new opportunities for harvesting various microalgal cells with different surface morphologies and chemical compositions

Reliability of self reported smoking status by pregnant women for estimating smoking prevalence: a retrospective, cross sectional study

Objective To determine what impact reliance on self reported smoking status during pregnancy has on both the accuracy of smoking prevalence figures and access to smoking cessation services for pregnant women in Scotland

Has primary care antimicrobial use really been increasing? Comparison of changes in different prescribing measures for a complete geographic population 1995-2014

Objectives To elucidate how population trends in total antimicrobials dispensed in the community translate into individual exposure. Methods Retrospective, population-based observational study of all antimicrobial prescribing in a Scottish region in financial years 1995, 2000 and 2005–14. Analysis of temporal changes in all antimicrobials and specific antimicrobials measured in: WHO DDD per 1000 population; prescriptions per 1000 population; proportion of population with ≥1 prescription; mean number of prescriptions per person receiving any; mean DDD per prescription. Results Antimicrobial DDD increased between 1995 and 2014, from 5651 to 6987 per 1000 population [difference 1336 (95% CI 1309–1363)]. Prescriptions per 1000 fell (from 821 to 667, difference –154, –151 to –157), as did the proportion prescribed any antimicrobial [from 39.3% to 30.8% (–8.5, –8.4 to –8.6)]. Rising mean DDD per prescription, from 6.88 in 1995 to 10.47 in 2014 (3.59, 3.55–3.63), drove rising total DDD. In the under-5s, every measure fell over time (68.2% fall in DDD per 1000; 60.7% fall in prescriptions per 1000). Among 5–64 year olds, prescriptions per 1000 were lowest in 2014 but among older people, despite a reduction since 2010, the 2014 rate was still higher than in 2000. Trends in individual antimicrobials provide some explanation for overall trends. Conclusions Rising antimicrobial volumes up to 2011 were mainly due to rising DDD per prescription. Trends in dispensed drug volumes do not readily translate into information on individual exposure, which is more relevant for adverse consequences including emergence of resistance.PostprintPeer reviewe