1,677 research outputs found
Adherence to Cardiovascular Disease Medications: Does Patient-Provider Race/Ethnicity and Language Concordance Matter?
BACKGROUND: Patientâphysician race/ethnicity and
language concordance may improve medication adherence
and reduce disparities in cardiovascular disease
(CVD) by fostering trust and improved patientâphysician
communication.
OBJECTIVE: To examine the association of patient
race/ethnicity and language and patientâphysician
race/ethnicity and language concordance on medication
adherence rates for a large cohort of diabetes
patients in an integrated delivery system.
DESIGN: We studied 131,277 adult diabetes patients in
Kaiser Permanente Northern California in 2005. Probit
models assessed the effect of patient and physician
race/ethnicity and language on adherence to CVD
medications, after controlling for patient and physician
characteristics.
RESULTS: Ten percent of African American, 11 % of
Hispanic, 63% of Asian, and 47% of white patients had
same race/ethnicity physicians.24% of Spanish-speaking
patients were linguistically concordant with their physicians.
African American (46%), Hispanic (49%) and Asian
(52%) patients were significantly less likely than white
patients (58%) to be in good adherence to all of their CVD
medications (p<0.001). Spanish-speaking patients were
less likely than English speaking patients to be in good
adherence (51%versus 57%, p<0.001). Race concordance
for African American patients was associated with adherence
to all their CVD medications (53% vs. 50%, p<0.05).
Language concordance was associated with medication
adherence for Spanish-speaking patients (51% vs. 45%,
p<0.05).
CONCLUSION: Increasing opportunities for patientâ
physician race/ethnicity and language concordance
may improve medication adherence for African American
and Spanish-speaking patients, though a similar
effect was not observed for Asian patients or Englishproficient
Hispanic patients
An investigation of wing buffeting response at subsonic and transonic speeds. Phase 2: F-111A flight data analysis. Volume 1: Summary of technical approach, results and conclusions
A detailed investigation of the flight buffeting response of the F-111A was performed in two phases. In Phase 1 stochastic analysis techniques were applied to wing and fuselage responses for maneuvers flown at subsonic speeds and wing leading edge sweep of 26 degrees. Power spectra and rms values were obtained. This report gives results of Phase 2 where the analyses were extended to include maneuvers flown at wing leading edge sweep values of 50 and 75.5 degrees at subsonic and supersonic speeds and the responses examined were expanded to include vertical shear, bending moment, and hingeline torque of the left and right horizontal tails. Power spectra, response time histories, variations of rms response with angle of attack and effects of wing sweep and Mach number are presented and discussed. Some Phase 1 results are given for comparison purposes
HighâThroughput Growth of Microscale Gold Bicrystals for SingleâGrainâBoundary Studies
The study of grain boundaries is the foundation to understanding many of the intrinsic physical properties of bulk metals. Here, the preparation of microscale thinâfilm gold bicrystals, using rapid melt growth, is presented as a model system for studies of single grain boundaries. This material platform utilizes standard fabrication tools and supports the highâyield growth of thousands of bicrystals per wafer, each containing a grain boundary with a unique tilt character. The crystal growth dynamics of the gold grains in each bicrystal are mediated by platinum gradients, which originate from the goldâplatinum seeds responsible for gold crystal nucleation. This crystallization mechanism leads to a decoupling between crystal nucleation and crystal growth, and it ensures that the grain boundaries form at the middle of the gold microstructures and possess a uniform distribution of misorientation angles. It is envisioned that these bicrystals will enable the systematic study of the electrical, optical, chemical, thermal, and mechanical properties of individual grain boundary types.Studies of single grain boundaries are enabled through the preparation of microscale gold bicrystals via rapid melt growth. This material platform supports the highâthroughput and highâyield growth of gold bicrystals on amorphous oxide. Crystallization is mediated by platinum doping, which decouples crystal nucleation from growth. These bicrystals offer model systems for the systematic study of individual defect properties.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151275/1/adma201902189-sup-0001-S1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151275/2/adma201902189.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151275/3/adma201902189_am.pd
An investigation of wing buffeting response at subsonic and transonic speeds. Phase 2: F-111A flight data analysis. Volume 2: Plotted power spectra
Plotted power spectra for all of the flight points examined during the Phase 2 flight data analysis are presented. Detailed descriptions of the aircraft, the flight instrumentation and the analysis techniques are given. Measured and calculated vibration mode frequencies are also presented to assist in further interpretation of the PSD data
Microdeletion of 6q16.1 encompassing EPHA7 in a child with mild neurological abnormalities and dysmorphic features: case report
<p>Abstract</p> <p>Background</p> <p>Of the fewer than 100 cases reported within the literature of constitutional deletions involving the long arm of chromosome 6, only five have been characterized using high-resolution microarray analysis. Reported 6q deletion patients show a high incidence of mental retardation, ear anomalies, hypotonia, and postnatal growth retardation.</p> <p>Results</p> <p>We report a 16-month-old male presenting with developmental delay and dysmorphic features who was found by array-based comparative genomic hybridization (aCGH) to have a ~2.16 Mb <it>de novo </it>deletion within chromosome band 6q16.1 that encompasses only two genes. Expression studies of the mouse homologue of one of the genes, the ephrin receptor 7 gene (<it>EPHA7</it>), have shown the gene functions during murine embryogenesis to form cortical domains, determine brain size and shape, and play a role in development of the central nervous system (CNS).</p> <p>Discussion</p> <p>Our results suggest that deletion of <it>EPHA7 </it>plays a role in the neurologic and dysmorphic features, including developmental delay, hypotonia, and ear malformations, observed in some 6q deletion patients.</p
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