578 research outputs found
A single intravenous injection of Kisspeptin evokes an increase in luteinising hormone in 15- and 18-week-old gilts
The pre-ovulatory luteinising hormone surge is affected by the sex ratio of a gilt's birth litter
The clock paradox in a static homogeneous gravitational field
The gedanken experiment of the clock paradox is solved exactly using the
general relativistic equations for a static homogeneous gravitational field. We
demonstrate that the general and special relativistic clock paradox solutions
are identical and in particular that they are identical for finite
acceleration. Practical expressions are obtained for proper time and coordinate
time by using the destination distance as the key observable parameter. This
solution provides a formal demonstration of the identity between the special
and general relativistic clock paradox with finite acceleration and where
proper time is assumed to be the same in both formalisms. By solving the
equations of motion for a freely falling clock in a static homogeneous field
elapsed times are calculated for realistic journeys to the stars.Comment: Revision: Posted with the caption included with the figure
Effect of Lowered Light Quality (R:FR Ratio) at Targeted Organs on Branching of Trifolium Repens
This report examined results from four similarly conducted experiments using Trifolium repens in which the R:FR ratio but not the photosynthetically active radiation (PAR) of incident light was altered at specific organ(s) of several successive phytomers or just at a single phytomer. Results indicate the local response to lowered R:FR light treatment was similar irrespective of the number of phytomers treated. This response pattern provides the means whereby plants can initiate strong localised responses to a heterogeneous light environment
Self-aligned nanoscale SQUID on a tip
A nanometer-sized superconducting quantum interference device (nanoSQUID) is
fabricated on the apex of a sharp quartz tip and integrated into a scanning
SQUID microscope. A simple self-aligned fabrication method results in
nanoSQUIDs with diameters down to 100 nm with no lithographic processing. An
aluminum nanoSQUID with an effective area of 0.034 m displays flux
sensitivity of 1.8 \mu_B/\mathrm{Hz}^{1/2}$ and high bandwidth, the SQUID on a tip is a highly
promising probe for nanoscale magnetic imaging and spectroscopy.Comment: 14 manuscript pages, 5 figure
Soil trampling in an Antarctic Specially Protected Area: tools to assess levels of human impact
The exposure of the Great Barrier Reef to ocean acidification
© 2016, Nature Publishing Group. All rights reserved. The Great Barrier Reef (GBR) is founded on reef-building corals. Corals build their exoskeleton with aragonite, but ocean acidification is lowering the aragonite saturation state of seawater (Ωa). The downscaling of ocean acidification projections from global to GBR scales requires the set of regional drivers controlling Ωa to be resolved. Here we use a regional coupled circulation-biogeochemical model and observations to estimate the Ωa experienced by the 3,581 reefs of the GBR, and to apportion the contributions of the hydrological cycle, regional hydrodynamics and metabolism on Ωa variability. We find more detail, and a greater range (1.43), than previously compiled coarse maps of Ωa of the region (0.4), or in observations (1.0). Most of the variability in Ωa is due to processes upstream of the reef in question. As a result, future decline in Ωa is likely to be steeper on the GBR than currently projected by the IPCC assessment report
Summer <i>f</i>-ratios and net community production in the Australian sector of Southern Ocean: contrasting regimes of nutrient availability and ecosystems functioning
The smoking cessation in pregnancy incentives trial (CPIT): study protocol for a phase III randomised controlled trial
Background:
Eighty per cent of UK women have at least one baby, making pregnancy an opportunity to help women stop smoking before their health is irreparably compromised. Smoking cessation during pregnancy helps protect infants from miscarriage, still birth, low birth weight, asthma, attention deficit disorder and adult cardiovascular disease. UK national guidelines highlight lack of evidence for effectiveness of financial incentives to help pregnant smokers quit. This includes a research recommendation: within a UK context, are incentives an acceptable, effective and cost-effective way to help pregnant women who smoke to quit?
Methods:
The Cessation in Pregnancy Incentives Trial (CPIT) III is a pragmatic, 42-month, multi-centre, parallel-group, individually randomised controlled superiority trial of the effect on smoking status of adding to usual Stop Smoking Services (SSS) support, the offer of up to £400 of financial voucher incentives, compared with usual support alone, to quit smoking during pregnancy.
Participants (n = 940) are pregnant smokers (age > 16 years, < 24 weeks pregnant, English speaking), who consent via telephone to take part and are willing to be followed-up in late pregnancy and 6 months after birth.
The primary outcome is cotinine/anabasine-validated abstinence from smoking in late pregnancy. Secondary outcomes include engagement with SSS, quit rates at 4 weeks from agreed quit date and 6 months after birth, and birth weight. Outcomes will be analysed by intention to treat, and regression models will be used to compare treatment effects on outcomes. A meta-analysis will include data from the feasibility study in Glasgow. An economic evaluation will assess cost-effectiveness from a UK NHS perspective. Process evaluation using a case-study approach will identify opportunities to improve recruitment and learning for future implementation.
Research questions include: what is the therapeutic efficacy of incentives; are incentives cost-effective; and what are the potential facilitators and barriers to implementing incentives in different parts of the UK?
Discussion:
This phase III trial in Scotland, England and Northern Ireland follows a successful phase II trial in Glasgow, UK. The participating sites have diverse SSS that represent most cessation services in the UK and serve demographically varied populations. If found to be acceptable and cost-effective, this trial could demonstrate that financial incentives are effective and transferable to most UK SSS for pregnant women.
Trial registration:
Current Controlled Trials, ISRCTN15236311. Registered on 9 October 2017
- …