On the boundary-layer structure of patterns of convection in rectangular-planform containers

This paper considers the structure of steady-state solutions of the Swift–Hohenberg equation describing convection in shallow rectangular-planform containers heated from below. The lateral dimensions of the planform are assumed to be much larger than the characteristic wavelength of convection. Results are restricted to patterns composed of rolls orthogonal to the sides of the rectangle in which case convection sets in at a critical value of the Rayleigh number in the form of rolls parallel to the shorter sides. This primary bifurcation from the conductive state of no motion produces a solution which subsequently undergoes a secondary bifurcation in which the low-amplitude motion near the shorter sides is replaced locally by cross-rolls perpendicular to the sides. This results in the formation of grain boundaries (or domain boundaries) within the fluid which mark the division between the different roll orientations.With increasing Rayleigh number the grain boundaries approach the sides of the rectangle and a boundary-layer structure is formed. In the present paper the method of matched asymptotic expansions is used to determine this boundary-layer structure and to predict the location of the grain boundaries. An interesting feature of the solution is that the grain boundaries develop significant curvature and bend into the corners of the rectangle, where the local solution is also determined.The results are compared with numerical computations of the secondary solution branch and with previous numerical and experimental work.</jats:p

Phosphorus Immobilization in Poultry Litter and Litter-amended soils with Aluminum, Calcium and Iron amendments

Arkansas produces approximately one billion broilers each year. Phosphorous (P) runoff from fields receiving poultry litter is believed to be one of the primary factors affecting water quality in Northwest Arkansas. Poultry litter contains approximately 20 g P kg-1, of which about 2 g P kg-1 is water soluble. Soils that have received repeated heavy applications of litter may have water soluble P contents of as high as 10 mg P Kg-1 soil. The objective of this study was to determine if soluble P levels could be reduced in poultry litter and litter-amended soils with Al,Ca, and/or Fe amendments. Poultry litter was amended with alum, sodium aluminate, quick lime, slaked lime, calcitic limestone, dolomitic limestone, gypsum, ferrous chloride, ferric chloride, ferrous sulfate and ferric sulfate, and incubated in the dark at 25°C for one week. Three soils which had been excessively fertilized with poultry litter were amended with alum, ferrous sulfate, calcitic limestone, gypsum and slaked lime and incubated for 4 weeks at 25 °C. In the litter studies, the Ca treatments were tested with and without CaF2 additions in an attempt to precipitate fluorapatite. At the end of the incubation period, the litter and soils were extracted with deionized water and soluble reactive P (SRP) was determined. SRP levels in the poultry litter were reduced from over 2,000 mg P kg-1 litter to less than 1 mg P kg-1 litter with the addition of alum, quick lime, slaked lime, ferrous chloride, ferric chloride, ferrous sulfate and ferric sulfate under favorable pH conditions. S.RP levels in the soils were reduced from approximately 5 mg P Kg-1 soil to less than 0.05 mg P Kg-1 soil with the addition of alum and ferrous sulfate under favorable pH conditions. Gypsum and sodium aluminate reduced SRP levels in litter by 50 to 60 percent while calcitic and dolomitic limestone were even less effective. In soils, the Ca amendments were less effective than the Al and Fe amendments, although slaked lime was effective at high pH. The results of these studies suggest that treating litter and excessively fertilized soils with some of these compounds, particularly alum, could significantly reduce the amount of SRP in runoff from littered pastures. Therefore, chemical additions to reduce SRP in litter and soil may be a best management practice in situations where eutrophication of adjacent water bodies due to P runoff has been identified. Preliminary calculations indicate that this .p ractice may be economically feasible. However, more research is needed to determine any beneficial and/or detrimental aspects of this practice

Islands of conformational stability for Filopodia

Filopodia are long, thin protrusions formed when bundles of fibers grow outwardly from a cell surface while remaining closed in a membrane tube. We study the subtle issue of the mechanical stability of such filopodia and how this depends on the deformation of the membrane that arises when the fiber bundle adopts a helical configuration. We calculate the ground state conformation of such filopodia, taking into account the steric interaction between the membrane and the enclosed semiflexible fiber bundle. For typical filopodia we find that a minimum number of fibers is required for filopodium stability. Our calculation elucidates how experimentally observed filopodia can obviate the classical Euler buckling condition and remain stable up to several tens of . We briefly discuss how experimental observation of the results obtained in this work for the helical-like deformations of enclosing membrane tubes in filopodia could possibly be observed in the acrosomal reactions of the sea cucumber Thyone, and the horseshoe crab Limulus. Any realistic future theories for filopodium stability are likely to rely on an accurate treatment of such steric effects, as analysed in this work

Evaluation of the efficacy and safety of high dose short duration enrofloxacin treatment regimen for uncomplicated urinary tract infections in dogs.

BackgroundUncomplicated urinary tract infections (UTI) in dogs usually are treated with antimicrobial drugs for 10-14 days. Shorter duration antimicrobial regimens have been evaluated in human patients.HypothesisA high dose short duration (HDSD) enrofloxacin protocol administered to dogs with uncomplicated UTI will not be inferior to a 14-day treatment regimen with amoxicillin-clavulanic acid.AnimalsClient-owned adult, otherwise healthy dogs with aerobic bacterial urine culture yielding ≥ 10(3) CFU/mL of bacteria after cystocentesis.MethodsProspective, multicenter, controlled, randomized blinded clinical trial. Enrolled dogs were randomized to group 1 (enrofloxacin 18-20 mg/kg PO q24h for 3 days) or group 2 (amoxicillin-clavulanic acid 13.75-25 mg/kg PO q12h for 14 days). Urine cultures were obtained at days 0, 10, and 21. Microbiologic and clinical cure rates were evaluated 7 days after antimicrobial treatment was discontinued. Lower urinary tract signs and adverse events also were recorded.ResultsThere were 35 dogs in group 1 and 33 in group 2. The microbiologic cure rate was 77.1 and 81.2% for groups 1 and 2, respectively. The clinical cure rate was 88.6 and 87.9% for groups 1 and 2, respectively. Cure rates between groups did not differ according to the selected margin of noninferiority.Conclusions and clinical importanceHDSD enrofloxacin treatment was not inferior to a conventional amoxicillin-clavulanic acid protocol for the treatment of uncomplicated bacterial UTI in dogs. Further research is warranted to determine if this protocol will positively impact owner compliance and decrease the emergence of antimicrobial resistance

Spin-Correlation Coefficients and Phase-Shift Analysis for p+3^3He Elastic Scattering

Angular Distributions for the target spin-dependent observables A$_{0y}$, A$_{xx}$, and A$_{yy}$ have been measured using polarized proton beams at several energies between 2 and 6 MeV and a spin-exchange optical pumping polarized $^3$He target. These measurements have been included in a global phase-shift analysis following that of George and Knutson, who reported two best-fit phase-shift solutions to the previous global p+$^3$He elastic scattering database below 12 MeV. These new measurements, along with measurements of cross-section and beam-analyzing power made over a similar energy range by Fisher \textit{et al.}, allowed a single, unique solution to be obtained. The new measurements and phase-shifts are compared with theoretical calculations using realistic nucleon-nucleon potential models.Comment: Submitted to Phys. Rev.

Dynamic model of fiber bundles

A realistic continuous-time dynamics for fiber bundles is introduced and studied both analytically and numerically. The equation of motion reproduces known stationary-state results in the deterministic limit while the system under non-vanishing stress always breaks down in the presence of noise. Revealed in particular is the characteristic time evolution that the system tends to resist the stress for considerable time, followed by sudden complete rupture. The critical stress beyond which the complete rupture emerges is also obtained

A SWOT analysis of health service access by men who have sex with men in South Africa: lessons for higher education institutions

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Preparing the Global Software Engineer

With a goal of preparing software engineering students for practice in today’s global settings, Uppsala University has for some years run courses involving global collaboration. The “IT in Society” course is one such course which applies an ‘Open Ended Group Project’ model, in partnership with a local health sector client and global educational partners. Within each iteration of the course, students across the partnering institutions are given a brief around an open-ended problem. They work in collaboration with their client and stakeholders to investigate options and produce a report with their findings and recommendations, informed by global perspectives. The report may or may not be supported by working software prototypes. We analyze student evaluations & reflections on the course to unpack their perceptions of software engineering, the perceived relevance of a global learning experience and its role in reshaping their identities as global software engineers

A random fiber bundle with many discontinuities in the threshold distribution

We study the breakdown of a random fiber bundle model (RFBM) with $n$-discontinuities in the threshold distribution using the global load sharing scheme. In other words, $n+1$ different classes of fibers identified on the basis of their threshold strengths are mixed such that the strengths of the fibers in the $i-th$ class are uniformly distributed between the values $\sigma_{2i-2}$ and $\sigma_{2i-1}$ where $1 \leq i \leq n+1$. Moreover, there is a gap in the threshold distribution between $i-th$ and $i+1-th$ class. We show that although the critical stress depends on the parameter values of the system, the critical exponents are identical to that obtained in the recursive dynamics of a RFBM with a uniform distribution and global load sharing. The avalanche size distribution (ASD), on the other hand, shows a non-universal, non-power law behavior for smaller values of avalanche sizes which becomes prominent only when a critical distribution is approached. We establish that the behavior of the avalanche size distribution for an arbitrary $n$ is qualitatively similar to a RFBM with a single discontinuity in the threshold distribution ($n=1$), especially when the density and the range of threshold values of fibers belonging to strongest ($n+1$)-th class is kept identical in all the cases.Comment: 6 pages, 4 figures, Accepted in Phys. Rev.