1,147 research outputs found

    Applications of Molecular Markers in Fisheries and Aquaculture

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    Organisms are characterized by unique biological attributes which enhance their fitness and survival to a particular environment. The driving force for enhanced survival and fitness is the genetic variation inherent in an individual as well as in a population. The information regarding genetic diversity and variation has wide application in research on evolution, conservation and management of natural populations. The advent of DNA cloning and sequencing methods have contributed immensely to the development of molecular taxonomy and population genetics over the last 2 decades. These modern methods have revolutionized the field of molecular taxonomy and population genetics with improved analytical power and precision

    Defining multimorbidity in people with HIV - what matters most?

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    PURPOSE OF REVIEW: Although multimorbidity (defined as the coexistence of multiple conditions) presents significant health challenges to people with HIV, there is currently no consensus on how it should be defined among this population. This review aimed to examine the definition of multimorbidity in existing studies among people with HIV (n = 22). RECENT FINDINGS: Variation in the definition of multimorbidity (in terms of the number and nature of conditions included) across studies among people with HIV was observed, with less than half (45%) reporting a selection criteria for conditions. The number of conditions considered ranged from 4 to 65. Certain conditions (e.g. stroke, myocardial infarction and chronic kidney disease) and risk factors (e.g. hypertension) were more frequently included, while other symptoms (e.g. joint pain, peripheral neuropathy and sleeping problems) and mental health conditions (e.g. anxiety and panic attacks) were rarely included in the definition of multimorbidity. SUMMARY: The definition of multimorbidity among people with HIV is highly variable, with certain conditions overlooked. We propose recommendations that researchers should consider when defining multimorbidity among this population to not only enable comparisons between studies/settings but also to ensure studies consider a person-centred approach that can accurately capture multimorbidity among people with HIV

    Understanding the conditions included in data-driven patterns of multimorbidity: a scoping review

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    BACKGROUND: Despite the growing utilization of data-driven methods to investigate multimorbidity patterns, there is currently no consensus or guidance on the conditions to include when identifying patterns. This scoping review aims to systematically examine the nature of conditions included in existing studies using data-driven techniques. METHODS: A comprehensive search of three electronic databases (MEDLINE, Web of Science and Scopus) was conducted to identify relevant publications from inception to 28 February 2022 using predefined search terms and inclusion/exclusion criteria. The reference lists and citations of relevant papers were also searched. RESULTS: Among 7326 search results, 5444 relevant articles were identified. After screening against the eligibility criteria, 60 articles were included in the review. Half of the reviewed studies reported selection criteria for conditions, with prevalence in the population of interest being the most common criterion (40%). Most studies included at least one neurological [59 (98.3%)], musculoskeletal [58 (96.7%)], respiratory [57 (95.0%)] or mental health [56 (93.3%)] condition. In contrast, only a small proportion of studies included skin [17 (28.3%)], infections [14 (23.3%)] or autoimmune conditions [10 (16.7%)]. Nine conditions (hypertension, diabetes, cancer, arthritis, COPD, asthma, depression, stroke and osteoporosis) were included by more than half of the studies. CONCLUSIONS: This review highlights the considerable heterogeneity among the conditions included in analyses of multimorbidity patterns. Researchers should provide a clear rationale for the selection of conditions to facilitate comparisons across studies and ensure reproducibility, as well as consider selecting a diverse range of conditions to capture the complexity of multimorbidity

    Toxic effect of copper sulphate on protein alterations in esturine fish, Mugil cephalus

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    Heavy metals are common pollutants of estuarine ecosystems where they induce adverse effects on the aquatic biota. Copper is one of the most toxic heavy metal to fish and consumption of fish after copper treatment in water may pose a serious risk to human health. Fishes are generally used as pollution indicators in water quality management. Chronic effects include reduced growth, shorter lifespan, reproductive problems, reduced fertility and behavioral changes. Esturine fish, Mugil cephalus is an important fin fish species of Uppanar estury in Cuddalore region having good nutritional values. Fishes living in close association with the sediment may accumulate copper sulphate. In the present observation, the toxic effects of the copper sulphate LC50 35 μg/L (CuSO4) on (10% and 30%) two sublethal concentrations of total protein in gill, liver and muscles tissues of the esturine fish, Mugil cephalus were estimated during the periods of 5, 10 and 15 days exposure. There is decreased in all tissues on comparison with control. The results indicated the toxic nature of the heavy metal copper sulphate

    A Child with X-Linked Agammaglobulinemia and Enthesitis-Related Arthritis

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    X-linked agammaglobulinemia (XLA) is a primary immune deficiency characterized by recurrent bacterial infections and profoundly depressed serum immunoglobulin levels and circulating mature B cells. We describe a 12-year-old boy with XLA and enthesitis-related arthritis (ERA). To date, there has been a paucity of reports of noninfectious inflammatory arthritis in children with XLA. This case illustrates that functional B cells and/or immunoglobulin are not required for ERA pathogenesis. In addition, this case suggests a possible link between immune deficiency, immune dysregulation, and rheumatic illness

    On the influence of spatial heterogeneity on an internal boundary layer at a short fetch

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    Surface layer meteorological data collected at a coastal site, at Vasco-Da-Gama (15°21′N, 73°51′E, 58.5m MSL) (13–18 July, 2002) with prevailing southwesterly surface winds are analyzed to study the characteristics of internal boundary layer at a short fetch using an instrumented tower (9 m). The spectral and turbulence characteristics of wind are compared with earlier measurements made at a comparatively homogeneous terrain and the standards available in literature. The study show the smaller eddies in the vertical velocity spectrum attains equilibrium with the underlying surface at a short fetch itself and follows spectral similarity. However, this is not followed by longitudinal and transverse velocity spectra under unstable as well as stable condition

    Influence of Parental Expectations on Young Children’s Approaches to Learning

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    This study explores the level of young children’s Approaches to Learning (ATL) in Shanxi, China, with a specific on the impact of parental expectations on ATL. 360 parents with preschool-aged children were enlisted for a comprehensive questionnaire survey. Applying descriptive statistics, inferential statistics, correlation, and regression analyses on the data gathered revealed that children's ATL was moderate, with noticeable variations based on gender and age. Importantly, parental expectations were positively correlated with children's ATL and remained a significant predictor even when accounting for age and gender, highlighting the strong relationship between parental expectations and early learning development. &nbsp

    Integrative taxonomy – Methods and Applications

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    Taxonomy is the discipline in biology aimed at characterizing and naming taxa and taxonomy plays a major role in conserving biodiversity. The central unit of taxonomy is species and generating biological information requires naming of species. Thousands of species are being named every year since the advent of Linnaean nomenclature in 1758. Alpha taxonomy relates to species level characterizations whereas beta taxonomy is related to higher level studies. The advent of new tools for species level identification of groups of organisms has contributed immensely to the rapid development of this branch of science. DNA sequencing technologies, access to museum collections, information about phyogenetics and phylogeography, advances in evolutionary studies and computer tomography have revolutionized conventional taxonomy in such a way that conventional taxonomy could be supplemented and complemented with information generated from all the above approaches. Species delimitation and a scientific consensus on naming could be achieved now by using a combination of different methods along with traditional taxonomy tools and this is the objective of integrative taxonomy. The term “integrative taxonomy” was coined by Dayrat, 2005 to describe a comprehensive approach to naming species

    5th International Symposium on Cage Aquaculture in Asia Book of Abstracts

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    The 5th International Symposium on Cage Aquaculture in Asia (CAA5) is being organised by the Asian Fisheries Society and the ICAR-Central Marine Fisheries Research Institute (CMFRI), in association with the Asian Fisheries Society Indian Branch, from the 25th to 28th of November 2015 at Kochi, India. The event will cover an array of topics related to cage culture under the broad headings of Marine Production Systems, Inland Production Systems, Breeding and Seed Production, Nutrition and Feed, Health and Environment Management and Economics, Livelihood and Policies
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