Magnetic asymmetry account of salientpole synchronous motors in mathematical simulation

Доклад посвящен учету магнитной несимметрии явнополюсных синхронных электродвигателей методом локальных сечений. Дается математическое описание разработанной версии метода, алгоритма и структуры его цифровой реализации. Приводятся результаты расчета нелинейной вектор-функции намагничивания машины по главному пути, пригодной для математического моделирования режимов явнополюсных синхронных машин и построения цифровых систем их регулирования.The paper is devoted to issues of account magnetic asymmetry of salient-pole synchronous motors by the method of locale sections. Mathematical formulation of developed method version and digital implementation structures of it are given. Results of nonlinear magnetization vector-function on the main magnetic path calculation are presented. This vector-function is useful for both synchronous salient-pole motor mathematical simulation and digital control system design of it

The features of the vector pwm for two-section frequency converter

Статья посвящена вопросам анализа режимов работы двухсекционного преобразователя частоты (ДСПЧ) на основе двух последовательно включенных инверторов напряжения. Рассматривается вопрос реализации векторной широтно-импульсной модуляции для исследуемого преобразователя. Предложен алгоритм векторной ШИМ, позволяющий исключить необходимость компенсации 2-й и 4-й гармоник, возникающих в предложенном ранее подходе к синтезу системы управления двухсекционным преобразователем с использованием односторонних опорных сигналов в узле ШИМ.This paper deals with analysis of two-section frequency converter based on two series-connected voltage inverters operating modes. The implementation issue of the vector pulse-width modulation for analyzed convertor is considered. The presented algorithm of the vector PWM eliminates the necessity to compensate the 2nd and 4th harmonics that occurs when using traditional sinusoidal PWM with asymmetric reference signal

Occult purulent pericarditis detected by indium-111 leukocyte imaging.

Leukocyte imaging with indium-111 is a relatively new technique which, to this point in time, has been discussed almost exclusively in the radiologic literature. Although this procedure has been used mainly to detect intra-abdominal infection, the thorax is routinely imaged along with the abdomen, and therefore detection of cardiac disease may be feasible. This case report is of a young woman after liver transplantation who developed occult purulent pericarditis initially detected by a leukocyte scan with indium-111. This case demonstrates that striking pericardial uptake on a whole-body indium-111 leukocyte scan can occur with purulent pericarditis, and it reemphasizes how insidiously purulent pericarditis may present in an immunosuppressed patient

Mathematical Simulation of Synchronous Reluctance Motors in Variable-Frequency Drive Applications

Доклад посвящен вопросам математического моделирования синхронного реактивного двигателя с учетом насыщения и взаимовлияния процессов по продольной и поперечной осям ротора. Дано краткое описание модифицированного метода локальных характеристик намагничивания, определяющего вектор-функцию намагничивания машины по главному пути с учетом отмеченных выше факторов. Приведены результаты математического моделирования пускового режима синхронного реактивного двигателя в составе частотно-регулируемого электропривода с векторной системой управления при настройке на различные законы управления. Полученная математическая модель пригодна для математического моделирования режимов синхронных реактивных машин и построения цифровых систем их управления.The paper is devoted to issues of mathematical simulation of synchronous reluctance motor with account of both saturation effect and mutual influence of processes in direct and quadrature axes of rotor. Brief modified method of locale magnetization characteristics description is given. It used for magnetization vector-function calculation with account of noted above effects. Mathematical simulation results of starting mode of synchronous reluctance motor in variable-frequency drive application with vector control system tuned to various control laws are given. Developed mathematical model of synchronous reluctance motor is valid for both mathematical simulations of synchronous reluctance machines modes and design digital control systems of it

Co-evolution of TH1, TH2 and TH17 Responses During Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89973/1/white-coevolution_th1_th2.pd

PPLook: an automated data mining tool for protein-protein interaction

<p>Abstract</p> <p>Background</p> <p>Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of interactions among proteins. There is a lack of tools to extract PPI, visualize and classify the results.</p> <p>Results</p> <p>We developed a PPI search system, termed PPLook, which automatically extracts and visualizes protein-protein interaction (PPI) from text. Given a query protein name, PPLook can search a dataset for other proteins interacting with it by using a keywords dictionary pattern-matching algorithm, and display the topological parameters, such as the number of nodes, edges, and connected components. The visualization component of PPLook enables us to view the interaction relationship among the proteins in a three-dimensional space based on the OpenGL graphics interface technology. PPLook can also provide the functions of selecting protein semantic class, counting the number of semantic class proteins which interact with query protein, counting the literature number of articles appearing the interaction relationship about the query protein. Moreover, PPLook provides heterogeneous search and a user-friendly graphical interface.</p> <p>Conclusions</p> <p>PPLook is an effective tool for biologists and biosystem developers who need to access PPI information from the literature. PPLook is freely available for non-commercial users at <url>http://meta.usc.edu/softs/PPLook</url>.</p

The gut microbiome in dogs with congestive heart failure: a pilot study

Compromised gut health and dysbiosis in people with heart failure has received a great deal of attention over the last decade. Whether dogs with heart failure have a similar dysbiosis pattern to what is described in people is currently unknown. We hypothesised that dogs with congestive heart failure have quantifiable dysbiosis compared to healthy dogs that are similar in sex and age. A total of 50 dogs (15 healthy dogs and 35 dogs with congestive heart failure) were prospectively recruited, and their faecal gut microbiome was assessed using 16S rRNA sequencing (Illumina MiSeq platform). There was no significant change in the microbial diversity and richness in dogs with congestive heart failure. However, there was an increase in abundance of Proteobacteria in the congestive heart failure group (p = 0.014), particularly due to an increase in the family Enterobacteriaceae (p = 0.002) and Escherichia coli (p = 0.033). We conclude that dogs with congestive heart failure have dysbiosis, and we show additional trends in our data suggesting that dogs may have a similar pattern to that described in people. The results of this study provide useful preliminary information and raise the possibility that dogs represent a clinically relevant animal model of dysbiosis in people with heart failure

A randomised clinical study to determine the effect of a toothpaste containing enzymes and proteins on plaque oral microbiome ecology

The numerous species that make up the oral microbiome are now understood to play a key role in establishment and maintenance of oral health. The ability to taxonomically identify community members at the species level is important to elucidating its diversity and association to health and disease. We report the overall ecological effects of using a toothpaste containing enzymes and proteins compared to a control toothpaste on the plaque microbiome. The results reported here demonstrate that a toothpaste containing enzymes and proteins can augment natural salivary defences to promote an overall community shift resulting in an increase in bacteria associated with gum health and a concomitant decrease in those associated with periodontal disease. Statistical analysis shows significant increases in 12 taxa associated with gum health including Neisseria spp. and a significant decrease in 10 taxa associated with periodontal disease including Treponema spp. The results demonstrate that a toothpaste containing enzymes and proteins can significantly shift the ecology of the oral microbiome (at species level) resulting in a community with a stronger association to health

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

In recent years, several associations between common chronic human disorders and altered gut microbiome composition and function have been reported(1,2). In most of these reports, treatment regimens were not controlled for and conclusions could thus be confounded by the effects of various drugs on the microbiota, which may obscure microbial causes, protective factors or diagnostically relevant signals. Our study addresses disease and drug signatures in the human gut microbiome of type 2 diabetes mellitus (T2D). Two previous quantitative gut metagenomics studies of T2D patients that were unstratified for treatment yielded divergent conclusions regarding its associated gut microbial dysbiosis(3,4). Here we show, using 784 available human gut metagenomes, how antidiabetic medication confounds these results, and analyse in detail the effects of the most widely used antidiabetic drug metformin. We provide support for microbial mediation of the therapeutic effects of metformin through short-chain fatty acid production, as well as for potential microbiota-mediated mechanisms behind known intestinal adverse effects in the form of a relative increase in abundance of Escherichia species. Controlling for metformin treatment, we report a unified signature of gut microbiome shifts in T2D with a depletion of butyrate-producing taxa(3,4). These in turn cause functional microbiome shifts, in part alleviated by metformin-induced changes. Overall, the present study emphasizes the need to disentangle gut microbiota signatures of specific human diseases from those of medication