Gender in endocrine diseases: role of sex gonadal hormones

Gender- and sex- related differences represent a new frontier towards patient-tailored medicine, taking into account that theoretically every medical specialty can be influenced by both of them. Sex hormones define the differences between males and females, and the different endocrine environment promoted by estrogens, progesterone, testosterone, and their precursors might influence both human physiology and pathophysiology. With the term Gender we refer, instead, to behaviors, roles, expectations, and activities carried out by the individual in society. In other words, “gender” refers to a sociocultural sphere of the individual, whereas “sex” only defines the biological sex. In the last decade, increasing attention has been paid to understand the influence that gender can have on both the human physiology and pathogenesis of diseases. Even the clinical response to therapy may be influenced by sex hormones and gender, but further research is needed to investigate and clarify how they can affect the human pathophysiology. The path to a tailored medicine in which every patient is able to receive early diagnosis, risk assessments, and optimal treatments cannot exclude the importance of gender. In this review, we have focused our attention on the involvement of sex hormones and gender on different endocrine diseases

Equilibrium phases of dipolar lattice bosons in the presence of random diagonal disorder

Ultracold gases offer an unprecedented opportunity to engineer disorder and interactions in a controlled manner. In an effort to understand the interplay between disorder, dipolar interaction and quantum degeneracy, we study two-dimensional hard-core dipolar lattice bosons in the presence of on-site bound disorder. Our results are based on large-scale path-integral quantum Monte Carlo simulations by the Worm algorithm. We study the ground state phase diagram at fixed half-integer filling factor for which the clean system is either a superfluid at lower dipolar interaction strength or a checkerboard solid at larger dipolar interaction strength. We find that, even for weak dipolar interaction, superfluidity is destroyed in favor of a Bose glass at relatively low disorder strength. Interestingly, in the presence of disorder, superfluidity persists for values of dipolar interaction strength for which the clean system is a checkerboard solid. At fixed disorder strength, as the dipolar interaction is increased, superfluidity is destroyed in favor of a Bose glass. As the interaction is further increased, the system eventually develops extended checkerboard patterns in the density distribution. Due to the presence of disorder, though, grain boundaries and defects, responsible for a finite residual compressibility, are present in the density distribution. Finally, we study the robustness of the superfluid phase against thermal fluctuations

Social Support\u27s Contribution to Reduced Welfare Dependency: Program Outcomes of Long Term Welfare Recipients

Long term welfare recipients participated in a state job training and welfare reform demonstration which provided education,job training, and supportive services via intensive case management. Social support research has focused on stress and physical and psychological health outcomes not welfarejob training and education outcomes. Job training and welfare to work policies and programs have not emphasized providing social supports but the supportive services of transportation and child care. Program outcomes at follow-up included: education and job training certificates, including GEDs with some still studying; jobs; and a 50% reduction in welfare receipt. Results of hierarchical regression analysis suggest a participant\u27s social support made a significant and meaningful contribution to reduced welfare dependency for hard to serve long term welfare recipients. Social support was more important than the length of time receiving welfare. Implications for social support theory, welfare to work policy and programs, job training, evaluation, and case management are discussed

The Left Bank Brasseries: The Evolution of a French-Inspired Restaurant

Due to the high failure rates of restaurants in the United States, many studies have come up with various reasons to explain the underlying causes of such a phenomenon. One key study by Parsa (2005) suggests, “Restaurant failures have been attributed to economic and social factors […]” and “Restaurant failures can be studied from economic, marketing, and managerial perspectives.” In particular, lack of capital is a major contributing factor for restaurants failure and researchers agree that a restaurant without a sufficient amount of capital will not survive because of three major expenses: overhead, labor, and food cost. Today’s service industry is indeed categorized by financial distress and this is very visible among owners and operators everyday. However, accurate and consistent internal management decisions may allow a restaurant to maintain financial stability. Managing and developing strong customer relationships overtime can help create a loyal following and that can translate into healthy and sustainable growth for the business. What roles do internal management practices and external market factors play in achieving sustainable success in the fine-dining restaurant industry? This research study will attempt to unveil how Left Bank Brasseries, a well-respected restaurant in Northern California, have sustained its success for twenty years. Using primary data collected from the management team in the form of interviews, this paper will identify the core competencies of the company and how it navigated this highly competitive landscape over the years. Particular attention will be paid to its financial performance, management practices, and levels of customer satisfaction and how these are related to the restaurant’s brand, which is essentially modeled on the French cuisine but managed the American way

In the Colonies

In the Colonies is a work of fiction. It tells the story of a young German harpist, C––, who is seduced into a life of luxury by a venal American, Sansone. She is invited to spend a year at his artists’ colony, where she works on composing a transcendent work of music and, in the process, realizes that she has lost sight of the material realities around her. Ultimately, she comes to realize that her single-minded pursuit of an ideal Beauty has driven her away from the very ideals she aspired to in the first place

The Left Bank Brasseries: The Evolution of a French-Inspired Restaurant

Due to the high failure rates of restaurants in the United States, many studies have come up with various reasons to explain the underlying causes of such a phenomenon. One key study by Parsa (2005) suggests, “Restaurant failures have been attributed to economic and social factors […]” and “Restaurant failures can be studied from economic, marketing, and managerial perspectives.” In particular, lack of capital is a major contributing factor for restaurants failure and researchers agree that a restaurant without a sufficient amount of capital will not survive because of three major expenses: overhead, labor, and food cost. Today’s service industry is indeed categorized by financial distress and this is very visible among owners and operators everyday. However, accurate and consistent internal management decisions may allow a restaurant to maintain financial stability. Managing and developing strong customer relationships overtime can help create a loyal following and that can translate into healthy and sustainable growth for the business. What roles do internal management practices and external market factors play in achieving sustainable success in the fine-dining restaurant industry? This research study will attempt to unveil how Left Bank Brasseries, a well-respected restaurant in Northern California, have sustained its success for twenty years. Using primary data collected from the management team in the form of interviews, this paper will identify the core competencies of the company and how it navigated this highly competitive landscape over the years. Particular attention will be paid to its financial performance, management practices, and levels of customer satisfaction and how these are related to the restaurant’s brand, which is essentially modeled on the French cuisine but managed the American way.https://scholar.dominican.edu/ug-student-posters/1002/thumbnail.jp

Equilibrium Phases of Tilted Dipolar Lattice Bosons

The recent advances in creating nearly degenerate quantum dipolar gases in optical lattices are opening the doors for the exploration of equilibrium physics of quantum systems with anisotropic and long-range dipolar interactions. In this paper we study the zero- and finite-temperature phase diagrams of a system of hard-core dipolar bosons at half-filling, trapped in a two-dimensional optical lattice. The dipoles are aligned parallel to one another and tilted out of the optical lattice plane by means of an external electric field. At zero-temperature, the system is a superfluid at all tilt angles $\theta$ provided that the strength of dipolar interaction is below a critical value $V_c(\theta)$. Upon increasing the interaction strength while keeping $\theta$ fixed, the superfluid phase is destabilized in favor of a checkerboard or a stripe solid depending on the tilt angle. We explore the nature of the phase transition between the two solid phases and find evidence of a micro-emulsion phase, following the Spivak-Kivelson scenario, separating these two solid phases. Additionally, we study the stability of these quantum phases against thermal fluctuations and find that the stripe solid is the most robust, making it the best candidate for experimental observation.Comment: 7 pages, 6 figure

Gynecomastia and hormones

Gynecomastia-the enlargement of male breast tissue in men-is a common finding, frequently observed in newborns, adolescents, and old men. Physiological gynecomastia, occurring in almost 25 % of cases, is benign and self-limited; on the other hand, several conditions and drugs may induce proliferation of male breast tissue. True gynecomastia is a common feature often related to estrogen excess and/or androgen deficiency as a consequence of different endocrine disorders. Biochemical evaluation should be performed once physiological or iatrogenic gynecomastia has been ruled out. Non-endocrine illnesses, including liver failure and chronic kidney disease, are another cause of gynecomastia which should be considered. Treating the underlying disease or discontinuing medications might resolve gynecomastia, although the psychosocial burden of this condition might require different and careful consideration

The sentiment analysis of tweets as a new tool to measure public perception of male erectile and ejaculatory dysfunctions

Twitter is a social network based on "tweets," short messages of up to 280 characters. Social media has been investigated in health care research to ascertain positive or negative feelings associated with several conditions but never in sexual medicin