852 research outputs found

    Chart Adequacy: Workshop and GEBCO Training

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    In July, 2015 the first NOAA Chart Adequacy Workshop was held in Silver Spring, Maryland, USA. Following a three-day workshop (14th to 16th July, 2015), four Nippon Foundation GEBCO students stayed at NOAA for an additional 10-day training at Office of Coast Survey’s Marine Chart Division. The key objective of the NOAA Chart Adequacy Workshop was to demonstrate techniques to evaluate the suitability of nautical chart products using chart quality information and publicly-available information. The attendees were cartographers, hydrographers and potential chart producers from hydrographic offices and government agencies around the world. The nations of the participants in the workshop included: Indonesia, Israel, Japan, Kenya, Malaysia, Philippines, South Korea, Sri Lanka, United Kingdom, United States and Venezuela. Through instructor presentations and GIS laboratory exercises (provided by Dr. Shachak Pe’eri and Lt Anthony Klemm), the participants generated the key layers that are involved in the NOAA procedure. A vessel traffic layer was generated by classification of navigational routes using Automatic Identification Systems (AIS) information. A bathymetric difference layer was generated by identifying areas that showed significant bathymetric changes identified by comparing Satellite-Derived Bathymetry (SDB) or other surveys of opportunity, with the existing chart. A hydrographic characteristics layer was generated by classification of chart quality information. Chart data (including the smooth sheet sounding sets) for the procedure were provided in a vector format with the appropriate metadata according to IHO S-57. Raster Navigational Charts were also used as a background and as a reference for the Bathymetric Difference layer

    Increased growing temperature reduces content of polyunsaturated fatty acids in four oilseed crops

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    Environmental temperature directly influences the lipid profile produced by oilseeds. If growing temperatures increase, as is predicted by current models, the precise profile of lipids produced are likely to change. This paper develops models to predict lipid profiles as a function of growing temperature. Data relating to lipid profiles of soybean (Glycine max), spring canola (Brassica napus), spring camelina (Camelina sativa), and sunflower (Helianthus annuus) were gathered from the literature and evaluated to examine the influence of temperature on relative production of oleic, linoleic, and linolenic acid. For each crop, a set of linear regressions was used to correlate temperature during the grain fill, defined as 30 days before harvest, with the molar percentages of oleic, linoleic, and linolenic acid present. An increase in temperature from 10 to 40°C resulted in an increase in the production of oleic acid and a decrease in the production of linoleic and linolenic acid in soybeans, canola, and sunflowers. Over the range of data available, the lipid profile of camelina was temperature insensitive. To test the validity of the correlations, the four crops were grown in a field study in Manhattan, Kansas simultaneously, in the same environment, in 2011. The correlations accurately predicted the field data for soybean, canola, and camelina but not for sunflower. The correlation for sunflower under-predicted the molar amount of oleic acid and over-predicted the molar amount of linoleic acid. This study indicates increasing growing temperatures from 10 to 40°C will result in more monounsaturated oils and less polyunsaturated oils in soybean, canola, and sunflower

    Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection

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    Citation: Udukala, D. N., Wang, H. W., Wendel, S. O., Malalasekera, A. P., Samarakoon, T. N., Yapa, A. S., . . . Bossmann, S. H. (2016). Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection. Beilstein Journal of Nanotechnology, 7, 364-373. doi:10.3762/bjnano.7.33Additional Authors: Ortega, R.;Toledo, Y.;Bossmann, L.;Robinson, C.;Janik, K. E.;Koper, O. B.;Motamedi, M.;Zhu, G. H.Proteases, including matrix metalloproteinases (MMPs), tissue serine proteases, and cathepsins (CTS) exhibit numerous functions in tumor biology. Solid tumors are characterized by changes in protease expression levels by tumor and surrounding tissue. Therefore, monitoring protease levels in tissue samples and liquid biopsies is a vital strategy for early cancer detection. Water-dispersable Fe/Fe3O4-core/shell based nanoplatforms for protease detection are capable of detecting protease activity down to sub-femtomolar limits of detection. They feature one dye (tetrakis(carboxyphenyl) porphyrin (TCPP)) that is tethered to the central nanoparticle by means of a protease-cleavable consensus sequence and a second dye (Cy 5.5) that is directly linked. Based on the protease activities of urokinase plasminogen activator (uPA), MMPs 1, 2, 3, 7, 9, and 13, as well as CTS B and L, human breast cancer can be detected at stage I by means of a simple serum test. By monitoring CTS B and L stage 0 detection may be achieved. This initial study, comprised of 46 breast cancer patients and 20 apparently healthy human subjects, demonstrates the feasibility of protease-activity-based liquid biopsies for early cancer diagnosis

    Shift-Volatility Transmission in East Asian Equity Markets

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    This paper attempts to provide evidence of "shift-volatility" transmission in the East Asian equity markets. By shift-volatility, we mean the volatility shifts from a low level to a high level, corresponding respectively to tranquil and crisis periods. We examine the interdependence of equity volatilities between Hong-Kong, Indonesia, Japan, Malaysia, the Philippines, Singapore, Thailand and the United States. Our main issue is whether shift-volatility needs to be considered as a regional phenomenon, or from a more global perspective. We find that the timing/spans of high volatility regimes correspond adequately to years historically documented as those of crises (the Asian crisis and the years following the 2008 crisis). Moreover, we suggest different indicators that could be useful to guide the investors in their arbitrage behavior in the different regimes: the duration of each state, the sensitivity of the volatility in a market following a change in the volatility in another market. Finally, we are able to identify which market can be considered as leading markets in terms of volatility

    Comparison of Filter Media for Wastewater Treatment by a Prototype Trickling Filter

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    The microbial process of wastewater treatment, attached growth, has significantly improved during recent years. Different filter media are used for microbial attached growth in trickling filters (TF) in the world. One of the main functions of filter media is the high surface area for the attachment of microorganisms to grow. Major wastewater treatment plants use stones as a medium for increasing the surface area in TFs. The proper grade of stone could not always be found within a reasonable distance from the wastewater treatment plant sites, significantly increasing transportation costs. Low-cost substitute materials, instead of stones, can reduce the cost of TF while increasing their treatment efficiency. This study attempted to use crushed waste polythene as a low-cost substitute material for stones. The objectives of this study were to evaluate the performance of prototype TF with crushed waste polythene and; to compare the treatment efficiency of two prototype TFs (with stone and with crushed waste polythene). Two prototype TFs were prepared using plastic barrels (250L) with two types of filter materials. The flow rate of the filters was 922mL/min and trickling filters were evaluated for two months for treatment efficiency. Water samples were taken before and after the trickling filter to determine the treatment efficiency. During the process of trickling filters, COD removal appeared to increase and it may be due to the adaptation of microbes to the new environment. The COD removal was comparatively higher in trickling filters with crushed polythene (62%) than in stones (42.6%). Almost similar results of pH and EC were found in both trickling filters. Total solids in treated wastewater were also almost similar in the two trickling filters. Based on the results of this study, it can be concluded that crushed polythene is a good alternative for stones in trickling filters.  Keywords: Crushed polythene, Filter material, Stone, Trickling filter, Wastewater&nbsp

    Eco-friendly bio-composite sheets: a study on the utilization of banana peels, cassava starch, and banana stem fibers

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    Massively using conventional plastics has led to significant environmental issues, including harm to ecosystems, wildlife, and human health, contributions to greenhouse gas emissions, and resource depletion through their extraction and production. Thus, there is an urgent imperative to seek sustainable alternatives like bio-composites. This research established the viability of banana peels and cassava starch for eco-friendly bio-composite sheets, offering insights into their properties and performance The bio-composite materials, composed of banana peels, cassava starch, banana stem fiber, glycerol, and acetic acid, were prepared in different weight-based proportions. The preparation process involved cleaning, drying, blending, and molding the materials to produce consistent bio-composite samples. The properties and performance of the composite samples were assessed for water absorption, moisture content, and tensile strength. Notably, the combination of banana peels and cassava in a 1:2 ratio, along with banana stem fiber, demonstrated favorable attributes, including reduced water absorption (ranging from 6.42 to 30.91%), desirable moisture content (ranging from 8.06 to 11.27%), and increased tensile strength (ranging from 5.345 to 11.892 MPa). These findings confirm the viability of using banana peels and cassava starch in producing bio-composite sheets, offering a sustainable alternative to conventional plastics. This study contributes to the field of sustainable materials by providing insights into the properties and performance of bio-composites, thereby supporting the development of eco-friendly bio-composite sheets.publishedVersio

    Stock Price Reaction to the Stock Splits Announcement of Listed Companies in the Colombo Stock Exchange

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    A stock split is a corporate event that directly impacts the number of a company’s shares and indirectly on stock prices. This study tests the effect of the stock splits on the share price of companies listed in the Colombo Stock Exchange during the periods of pre and post stock split announcement in accordance with the Efficient Market Hypothesis. The main objective of this paper is to identify the overall impact of a stock split announcement on stock prices. This study analyses 88 annual stock splits during the ten (10) year period from 2009 to 2019 by taking the listed companies in the Colombo Stock Exchange into consideration. It uses the event study methodology to test the market efficiency of the Colombo Stock Exchange, and the market model is run with the aid of abnormal returns, which are calculated based on daily closing stock prices and the All-Share Price Index. For analysing the results, the graphical analysis and t statistics have been utilized. According to the event day average abnormal return, the majority of stock splits were more negative than positive with a significant t value at 5% by indicating that investors were taking the stock split announcement as bad news just after the split announcement was released. Each day with a significant Average Abnormal Return shows more positives than negatives. Graphical results have shown both Average Abnormal Return, and Cumulative Average Abnormal Return has remained continuously negative up to 18 and 25 days, respectively, by implicating that stock splits have made a deleterious impact on stock return. This study finally concludes that the information regarding the stock splits has not been absorbed efficiently by the market because the market reactions before and after the date of the split announcement were significant at 5%, although the Average Abnormal Return got a quick reaction to the announcement. Furthermore, results had not provided evidence for Semi-Strong Form efficiency of the Colombo Stock Exchange since the significant stock price adjustments before and after the event day was noticed. By this study, the policymakers and investors are convinced that all information has not been incorporated into stock prices in making their decisions. Keywords: Efficient market hypothesis; Event study methodology; Signalling theory; Sri Lanka; Stock split
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