Cyberspace and Crime Engineering: A Sociological Review

The complexity of cyberspace and its benefits to modern economies have been substantially accentuated in literature. Cyber environment permits different shades of activism and it as well coalescences myriad of application, pursuits and users both converging in space with the absence of censorship or control. This expanded patronage of space presents gamut of threat to lawful utilization and sufficiently promote insecurity to both financial and information concerns of users consequently, this paper engages a review of the rising rate of vulnerabilities in the cyberspace and contextualized this within the framework of modernist theory of space. It also establishes affinity between space, modern crimes and resultant victimization. Finally, the paper proffer solution to the challenges of cyberspace induced crimes

Spouse-sharing and Experiences with Sexually Transmitted Diseases Among the Okun of Nigeria

This paper examines the practice of spouse sharing and its influence on having multiple sex partners and self-reported STD experiences among the Okun people of Nigeria. It also examines the coping strategies of the people with respect to STDs. Primary data were collected through the administration of questionnaires to 1029 respondents (518 men and 511 women) and through focus group discussions. Respondents who participate in spouse sharing are more likely to have more sex partners simultaneously than those who do not, and multiple sexual partnering is a significant risk factor in the reporting of STD experience. Knowledge of the link between risky sexual practices involving multiple sexual partnerships and the prevalence of STDs is poor. Although most respondents are knowledgeable about the symptoms of STDs like gonorrhea and syphilis, and to a lesser extent HIV/AIDS, they are less informed about how best to prevent these diseases. The use of condoms is low among the men while a strong confidence is expressed in traditional medicine and self-protective practices with unproven efficacy. The study recommends the provision of more information, education and communication to expand knowledge of STDs, and the probable impact of spouse sharing in fueling the spread of STDs, including HIV/AIDS

Photovoltaic Generating System Parameter Sizing for Building

Small to medium sized battery storage required to address the intermittency challenge of the energy of solar radiation could be achieved by appropriate sizing of the photovoltaic system parameters like photovoltaic module (PVM) number and battery capacity. This paper presents the results of evaluation of the optimum parameter values in sizing of stand-alone photovoltaic (PV) system that satisfies building energy demand, with almost zero Loss of Power Supply Probability (LPSP). A time step simulation of system performance based on energy balance for various combinations of PV numbers and battery capacities was employed. (Three seasons of operation were considered; rainy, hot and hot/dry). The rainy season result indicating high storage capacity requirement of about (2500-Ah), is of highest cost compared to other seasons. Stand-alone photovoltaic system size that will assuage the intermittency challenge; mitigate peak demand costs and provide near zero LPSP was determined. Keywords: loss of power supply probability, photovoltaic, energy demand, parameter sizing, stand-alon

FOREIGN POLICY MAKING AND IMPLEMENTATION UNDER OLUSEGUN OBASANJO'S ADMINISTRATION (1999-2007)

This paper examines Nigeria's foreign policy making and implementation under Olusegun Obasanjo'scivilian administration. Therefore, th is work interrogateshow Obasanjo's administration formulated and implemented Nigeria's foreign policy. To successfully accomplish this task, both primary and secondary data were collected. Interviews conducted with principal actors and secondary data obtained from books, journals, magazines, bulletins, newspapers and government records were analysed to achieve the objectives of the study.Among other findings, the study observed that there were structures put in place for Nigeria's foreign policy making processes under Obasanjo's c ivilian rule. It is important to note also, that the actual foreign policies formulated were dictated primarily by Obasanjo's personality and executive leadership decisions. The paperthereforc recommends, among others, that strong institutions should be put in place to facilitate foreign policy _ making and execution, and there should be standard operational procedures in foreign policy making and execution that would strengthen institutions and limit personalities

Malaria Control and Household Resource Allocation in Ido-Local Government, Nigeria

In a bid to contribute to the knowledge base needed for effective malaria control, this research work examined the control of malaria among rural households and the impact it has on the allocation of household resources in Ido-Local Government Area (LGA) of Oyo State. The research was carried out as a descriptive cross-sectional study of randomly selected household heads and health workers in Ido-LGA. The Health Belief Model was adopted to predict health behaviours and explain behavioural responses to treatment through adequate allocation of household resources

Near-Surface Investigation of Groundwater Contamination in the Regolith Aquifer of Palladan, Zaria using Borehole log and Tomography Techniques

Abstract: Two geophysical Tomography techniques-Electrical resistivity and Seismic refraction were used to investigate the subsurface of a potentially polluted dumpsite in Palladan a densely populated area of Zaria, with a view to examining the possible subsurface distribution of groundwater contamination plume. The presence of domestic wells in the residences of the people which are distances 10.0 to 30.0 m from the dump facilitated analysis of water chemistry to enhance the geophysical interpretation. The groundwater level in the dumpsite site was found to be higher than the surrounding area, thereby creating a local deviation from the regional groundwater flow. Due to this the contaminants from the waste site spread out in the nearby soil and groundwater. The resistivity models clearly show a top layer of about 10.0 m thickness with low resistivity, whereas the resistivity has an inverse correlation with distance from the waste disposal site. Bore hole log shows that the top upper 10.0 m of soil consists of loose permeable laterite with high water content followed by a layer of degraded sand before the weathered basement which suggests the possibility of the contamination penetrating deeper into the regolith aquifer. This agrees with the result of the water chemistry analysis which shows elevation in concentration of contaminants above the WHO guidelines. The borehole log also indicated the presence of fracture basement at a depth of 23.0 m this correlated well with the Seismic refraction result. The study therefore suggests that these fractures also facilitate the migration of the contaminants. Based on the combined results, the contamination plume seems to have migrated not less than 500.0 m in the southern direction which is also the direction of hydraulic gradien

A cross-sectional study on urogenital schistosomiasis in children; haematuria and proteinuria as diagnostic indicators in an endemic rural area of Nigeria

Background: Rapid and accurate diagnosis is necessary for the management of schistosomiasis in endemic areas.Objective: To assess the burden of urogenital schistosomiasis and the diagnostic efficiency of morbidity indicators of the disease in an endemic rural community of Nigeria.Methods: A cross-sectional school-based study was conducted. Urine samples of 487 pupils were screened microscopically for S. haematobium and tested for haematuria and proteinuria using chemical reagent strips.Results: The prevalence and intensity of infection were 57.1% and 45.0 eggs/10 mL urine respectively. Prevalence of infection in male (54.1%) and female (60.3%) individuals showed no significant variation (P>0.05). However, prevalence of infection was age dependent with those in age groups 3-5 and 12-14 years having the least and highest prevalence of infection respectively (P<0.05). Microhaematuria and proteinuria varied significantly with ages of the pupils with least (14.0, 40.0%) and highest (60.0, 80.0%) prevalence recorded in age groups 3-5 and 15-19 years respectively (P<0.05). Proteinuria showed higher sensitivity (80.3%) compared to microhaematuria (73.3%).Conclusion: Schistosomiasis is highly endemic in the study area and the use of microhaematuria and proteinuria for mapping the infected  population prior treatment could be adopted.Key words: Schistosomaisis, haematuria, proteinuria, Nigeri

NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss

Background: The NCI-MATCH trial is the largest national study (1173 sites) for ptswith relapsed/ refractory solid tumors, lymphomas and myeloma, which assigns tar-geted therapies based on individual tumor molecular alterations detected using theadapted Oncomine AmpliSeq panel (143 genes) and immunohistochemistry (IHC).We hypothesized that patients with PTEN-deficient cancers enrolled to Arms N and Pmay benefit from treatment with the PI3K beta-selective inhibitor GSK2636771. Methods: Eligibility: relapsed/refractory ca, good end-organ function, and ECOG PS ≤ 1. Pts were screened for molecular alterations by centralized testing on fresh tumor biopsy and had deleterious PTEN mut/del without loss of expression (Arm N) or complete loss of cytoplasmic and nuclear PTEN staining on IHC (Arm P), and no other aberrations activating the PI3K/MTOR and MAPK pathways (mut in PIK3CA, PIK3R1, BRAF, KRAS, AKT1, TSC1/2, mTOR, RHEB, NF2, NRAS, HRAS). Pts received GSK2636771 400mg/day (28-days cycles). RECIST 1.1 overall response rate (ORR) was the primary endpoint. Results: Of 59 enrolled pts, 56 were eligible and received treatment. Of 22 pts with PTEN mut/del (Arm N: 6 uterine, 2 breast, 2 prostate, 2 head/neck ca, 10 other), all are off treatment as of analysis (14 disease progression, 4 for adverse events [AEs], 4 other). One pt (4.5%) with prostate ca (PTEN deletion, MPRSS2-ERG fusion) attained a partial response (-42%). Of 7 (32%) pts with stable disease (SD), 2 had SD \u3e 6 months (uterine leiomyosarcoma; endometrial carcinoma). Of 34 pts with loss of PTEN protein by IHC (Arm P: 7 prostate, 6 breast, 3 squamous anal ca, 2 cholangiocarcinoma, 16 other), all are off treatment as of analysis (26 disease progression, 4 for AE, 4 other). Of 9 (37.5%) pts with SD, 3 had SD \u3e 6 months (prostate cancer; squamous bladder cancer, squamous anal cancer). Median progression-free survival was 1.8 months for both arms. Gr ≥ 3 treatment-related (tr) reversible toxicities were experienced by 30% (7) and 20% (7) of pts in arms N and P, respectively. No tr Gr 5 toxicities were observed in either arm. Conclusions: Single agent GSK2636771 has very modest activity in ca with PTEN gene mutation/deletion and/or PTEN protein loss

Assessment of Physicochemical Parameters and Heavy Metals in Sagamu Abattoir Waste Water Ogun State, Nigeria

Abattoir wastewater is a great threat to environmental safety. This study was aimed at assessing the physiochemical constituents using standard methods and some heavy metals using Agilent Microwave Atomic Emission Spectrometer (MP-AES) 4200 model after sample digestion of wastewater from three (3) major abattoirs in Sagamu, Ogun State, Nigeria. The sample was digested using a mixture of nitric acid, hydrochloric acid and hydrogen peroxide. The digested samples were then analyzed for heavy metals. Data from the physicochemical characterization show that pH, TS, TDS, TSS and COD ranged from; (5.8 – 6.2), (11500 – 27733.33), (5500 – 9066.67), (6000 – 18666.67), and (1507.67 – 3671) respectively. The assessed heavy metals are in the range (mg/L): Zn (0.132-0.337), Cu (0.091 – 0.516), Mn (0.410 – 0.994), Fe (5.294 – 15.44), V (0.132 – 0.32), Cd (0.036 – 0.119), Ni (0.029 – 0.17), Pb (0.136 – 0.234), Cr (0.299 – 1.277), and Co (0.015 – 0.079). Zn, Cu and Fe are essential metals within tolerable limits except Mn that exceeded the limits of World Health Organization (0.04 mg/L) but below Federal Ministry of Environment (5 mg/L) while Ni, Pb and Chromium are above permissible limits in all samples.  The pretreatment of the wastewater before discharging into environment is highly recommended and more research should be done on remediation to reduce the abattoir wastewater heavy metals concentration and the effect it is having on the ecosystem and the environment at large

Community perceptions of a malaria vaccine in the Kintampo districts of Ghana.

BACKGROUND: Malaria remains the leading cause of morbidity and mortality in sub-Saharan Africa despite tools currently available for its control. Making malaria vaccine available for routine use will be a major hallmark, but its acceptance by community members and health professionals within the health system could pose considerable challenge as has been found with the introduction of polio vaccinations in parts of West Africa. Some of these challenges may not be expected since decisions people make are many a time driven by a complex myriad of perceptions. This paper reports knowledge and perceptions of community members in the Kintampo area of Ghana where malaria vaccine trials have been ongoing as part of the drive for the first-ever licensed malaria vaccine in the near future. METHODS: Both qualitative and quantitative methods were used in the data collection processes. Women and men whose children were or were not involved in the malaria vaccine trial were invited to participate in focus group discussions (FGDs). Respondents, made up of heads of religious groupings in the study area, health care providers, traditional healers and traditional birth attendants, were also invited to participate in in-depth interviews (IDIs). A cross-sectional survey was conducted in communities where the malaria vaccine trial (Mal 047RTS,S) was carried out. In total, 12 FGDs, 15 IDIs and 466 household head interviews were conducted. RESULTS: Knowledge about vaccines was widespread among participants. Respondents would like their children to be vaccinated against all childhood illnesses including malaria. Knowledge of the long existing routine vaccines was relatively high among respondents compared to hepatitis B and Haemophilus influenza type B vaccines that were introduced more recently in 2002. There was no clear religious belief or sociocultural practice that will serve as a possible barrier to the acceptance of a malaria vaccine. CONCLUSION: With the assumption that a malaria vaccine will be as efficacious as other EPI vaccines, community members in Central Ghana will accept and prefer malaria vaccine to malaria drugs as a malaria control tool. Beliefs and cultural practices as barriers to the acceptance of malaria vaccine were virtually unknown in the communities surveyed