718 research outputs found

    Borel Degenerations of Arithmetically Cohen-Macaulay curves in P^3

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    We investigate Borel ideals on the Hilbert scheme components of arithmetically Cohen-Macaulay (ACM) codimension two schemes in P^n. We give a basic necessary criterion for a Borel ideal to be on such a component. Then considering ACM curves in P^3 on a quadric we compute in several examples all the Borel ideals on their Hilbert scheme component. Based on this we conjecture which Borel ideals are on such a component, and for a range of Borel ideals we prove that they are on the component.Comment: 20 pages, shorter and more effective versio

    Rotation of Low-mass Stars in Taurus with K2

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    We present an analysis of K2 light curves (LCs) from Campaigns 4 and 13 for members of the young (~3 Myr) Taurus association, in addition to an older (~30 Myr) population of stars that is largely in the foreground of the Taurus molecular clouds. Out of 156 of the highest-confidence Taurus members, we find that 81% are periodic. Our sample of young foreground stars is biased and incomplete, but nearly all stars (37/38) are periodic. The overall distribution of rotation rates as a function of color (a proxy for mass) is similar to that found in other clusters: the slowest rotators are among the early M spectral types, with faster rotation toward both earlier FGK and later M types. The relationship between period and color/mass exhibited by older clusters such as the Pleiades is already in place by Taurus age. The foreground population has very few stars but is consistent with the USco and Pleiades period distributions. As found in other young clusters, stars with disks rotate on average slower, and few with disks are found rotating faster than ~2 days. The overall amplitude of the LCs decreases with age, and higher-mass stars have generally lower amplitudes than lower-mass stars. Stars with disks have on average larger amplitudes than stars without disks, though the physical mechanisms driving the variability and the resulting LC morphologies are also different between these two classes

    Shintaido in the elderly: the new way for physical and psychological health

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    The research aims to investigate the effects of a Shintaido practice in terms of physical and psychological functioning in a group of elderly. Forty seniors, of both gender, with a mean age of (69 ± 6) years, self-sufficient and without highly invalidating diseases participated in the study. The experimental group (EG) attended the Shintaido physical training of 20 weeks (1 hour per session, twice a week), while the control group (CG) maintained his usual routine. The exercise protocol included specific activities of joint mobility, balance and breathing. At the begin and at the end of intervention were administered to both groups the following validated instruments: 1) One-leg Stance test for the measure of monopodalic static balance; 2) 6-Minutes Walking test for the endurance assessment; 3) Self-Efficacy Perception in Physical Activity (APEF) questionnaire for the selfefficacy evaluation. Data were treated with the not-parametric test for paired and unpaired samples, the Spearman correlation and the linear regression. The results show that: 1) the EG improves the endurance in walking and the monopodalic balance as well as his self-efficacy after the Shintaido program; 2) there are strong associations among Shintaido physical activity and physical/psychological variables; 3) there is a mediating effect of walking endurance between the participation to Shintaido training and the self-efficacy. The results suggest that a well structured Shintaido training can help to maintain a good level of physical and psychological functioning in old people

    Unusual Presentation of Localized Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Mimicking Poorly Differentiated Gastric Adenocarcinoma

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    The risk of misdiagnosing neoplastic cells typically infiltrating an epithelium forming a lymphoepithelial lesion as poorly differentiated gastric cancer in endoscopic biopsies, particularly in low-grade mucosa-associated lymphoid tissue (MALT) lymphomas, is described. A 76-year-old woman was referred for management of a poorly differentiated gastric adenocarcinoma. Diagnostic endoscopy in our unit showed a 2 cm raised, submucosal lesion with central erosion in the upper body of the stomach, but repeat biopsies of the lesion were interpreted as inflamed gastric mucosa and negative for malignancy. Systematic gastric biopsies to rule out any foci of MALT lymphoma changes were also negative. Therefore, endoscopic submucosal dissection was performed to obtain an accurate specimen. Histology revealed centrocyte-like cells and a lymphoepithelial lesion invading into the mucosa with obliteration of the gastric glands, which was initially interpreted as poorly differentiated adenocarcinoma

    Dynamics of SNARE Assembly and Disassembly during Sperm Acrosomal Exocytosis

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    The dynamics of SNARE assembly and disassembly during membrane recognition and fusion is a central issue in intracellular trafficking and regulated secretion. Exocytosis of sperm's single vesicle—the acrosome—is a synchronized, all-or-nothing process that happens only once in the life of the cell and depends on activation of both the GTP-binding protein Rab3 and of neurotoxin-sensitive SNAREs. These characteristics make acrosomal exocytosis a unique mammalian model for the study of the different phases of the membrane fusion cascade. By using a functional assay and immunofluorescence techniques in combination with neurotoxins and a photosensitive Ca(2+) chelator we show that, in unactivated sperm, SNAREs are locked in heterotrimeric cis complexes. Upon Ca(2+) entry into the cytoplasm, Rab3 is activated and triggers NSF/α-SNAP-dependent disassembly of cis SNARE complexes. Monomeric SNAREs in the plasma membrane and the outer acrosomal membrane are then free to reassemble in loose trans complexes that are resistant to NSF/α-SNAP and differentially sensitive to cleavage by two vesicle-associated membrane protein (VAMP)–specific neurotoxins. Ca(2+) must be released from inside the acrosome to trigger the final steps of membrane fusion that require fully assembled trans SNARE complexes and synaptotagmin. Our results indicate that the unidirectional and sequential disassembly and assembly of SNARE complexes drive acrosomal exocytosis
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