Turn-Type Structures in Amide- and Triazole-Linked Carbopeptoids

Herein, we present the synthesis and spectroscopic studies of the furanose-based amide- and triazole-linked carbopeptoids. Acetonide protected furanose rings are stereochemically defined molecular scaffolds that impose certain rigidity to the oligomeric structures made from them. Linking with an amide linkage provides open sites for the formation of intramolecular hydrogen bonds when incorporated in the larger molecules, while triazole linkers add conformational stability and rigidity

Synthesis and Spectroscopic Studies of Novel Carbopeptoids

Using readily available D-glucose as starting material we have synthesized oligosaccharides with different linker

Analysis of Conformational Preferences of Triazole Containing Carbopeptoids

Acetonide protected furanose rings are stereochemically defined molecular scaffolds that impose certain rigidity to the oligomeric structures made from them. Linking with an amide provides open sites for the formation of intramolecular hydrogen bonds when incorporated in the larger molecules, while triazole linkers add conformational stability and rigidity. Herein we present the synthesis and spectroscopic studies of the furanose-based amide- and triazole-linked carbopeptoides