452 research outputs found
Phase diagram of the non-uniform chiral condensate in different regularization schemes at T=0
We show that the qualitative picture of the phase diagram which includes the
non-uniform chiral phase and 2SC superconducting phase is independent of the
considered regularization schemes. We also demonstrate that the quantitative
results agree with each other reasonably for the set of so called
"relativistic" regularization schemes. On the other hand the "non-relativistic"
momentum cut-off is clearly differ from the others
Immunohistochemical studies on brain nitric oxide synthase (bNOS) in the male genital accessory glands of the rat during postnatal development
The aim of the study was to investigate the presence, localisation and function
of brain nitric oxide synthase (bNOS) in the male genital accessory glands of rats
in the course of their postnatal development. Localisation of the bNOS was
immunocytochemically investigated in the epididymis, seminal vesicle and ventral
prostate of male Wistar strain rats at 1, 5, 10, 20, 28, 35, 45 and 59 days of
age. The method employed involved mouse monoclonal antibodies against rat
bNOS in combination with tyramide signal amplification (CSA). The intensity of
the reaction in the organs studied was determined using computer software to
demonstrate the optical density of the reaction product obtained. In the epididymis
a weak reaction was observed in the connective tissue/muscular sublayer
on the 28th and 45th days of life. In the seminal vesicle and ventral prostate
a positive reaction appeared in the epinuclear portions of glandular epithelial
cells on the 20th day of life, reaching a maximum intensity on the 28th day and
thus before the rats reached maturity. The results obtained allow the conclusion
to be drawn that nitric oxide resulting from bNOS-activity participates in the
processes of differentiation and of function in the epididymis, seminal vesicle
and ventral prostate
Investigation of Prediction Accuracy, Sensitivity, and Parameter Stability of Large-Scale Propagation Path Loss Models for 5G Wireless Communications
This paper compares three candidate large-scale propagation path loss models
for use over the entire microwave and millimeter-wave (mmWave) radio spectrum:
the alpha-beta-gamma (ABG) model, the close-in (CI) free space reference
distance model, and the CI model with a frequency-weighted path loss exponent
(CIF). Each of these models have been recently studied for use in standards
bodies such as 3GPP, and for use in the design of fifth generation (5G)
wireless systems in urban macrocell, urban microcell, and indoor office and
shopping mall scenarios. Here we compare the accuracy and sensitivity of these
models using measured data from 30 propagation measurement datasets from 2 GHz
to 73 GHz over distances ranging from 4 m to 1238 m. A series of sensitivity
analyses of the three models show that the physically-based two-parameter CI
model and three-parameter CIF model offer computational simplicity, have very
similar goodness of fit (i.e., the shadow fading standard deviation), exhibit
more stable model parameter behavior across frequencies and distances, and
yield smaller prediction error in sensitivity testing across distances and
frequencies, when compared to the four-parameter ABG model. Results show the CI
model with a 1 m close-in reference distance is suitable for outdoor
environments, while the CIF model is more appropriate for indoor modeling. The
CI and CIF models are easily implemented in existing 3GPP models by making a
very subtle modification -- by replacing a floating non-physically based
constant with a frequency-dependent constant that represents free space path
loss in the first meter of propagation.Comment: Open access available at:
http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=743465
Diagnosis of the functional state of transformed acid soils agroecosystems depending on long-term anthropogenic loads
Received: March 6th, 2021 ; Accepted: June 11th, 2021 ; Published: June 22nd, 2021 ; Correspondence: [email protected] main priority of agro-industrial production has always been and remains to provide
the global population and its yearly increments with food. The issue of soil fertility improvement
is still the most important task of agricultural science. The assessment of the agroecological
condition of Albic Stagnic Luvisol using carbon dioxide emission, redox potential, and biotic
activity was carried out, based on modern methodological approaches, such as soil quality
evaluation via ecologically-related biological parameters. Carbone dioxide emission, redox, and
biological processes in long-term stationary experiment depend on the degree of soil acidity
reduction. Soil acidification can be minimized through chemical melioration with the combined
application of different doses of mineral fertilizers and manure. It was found that carbon dioxide
emission is optimal in an organo-mineral fertilizing system with application of 10 t of manure per
1 ha and N65Đ 68K68 with lime dose (2.5 t ha-1
) calculated according to pH buffering capacity. It is
due to oxidative and moderately oxidative conditions created. This organo-mineral fertilizing
system also increases the number of aerobic bacteria and overall biological activity. The mineral
fertilization and the use of Albic Stagnic Luvisol without fertilizers are accompanied by increased
mineralization, growth of reductive processes, and the number of moulds. Studies have shown
that it is advisable to include CO2 emission, redox potential and biological activity along with
physicochemical and agrochemical soil properties to assess the influence of different
anthropogenic loads on soil formation
The content of mobile aluminium compounds depending on the long-term use of various fertilizing and liming systems of Albic Pantostagnic Luvisol
Received: January 31st, 2023 ; Accepted: April 27th, 2023 ; Published: May 16th, 2023 ;
Correspondence: [email protected], climate change is exacerbating the problems of efficient and environmentally
friendly use of acidic soils, which are widespread in Ukraine. At the same time, the role of mobile
aluminium compounds in acidity formation is also becoming increasingly important. In this
regard, chemical amelioration remains a primary and very important factor in the system of
resource-saving and environmentally friendly agricultural measures for the efficient and balanced
use of acidic soils. Therefore, the main objective of the research is to establish scientifically sound
doses of chemical ameliorant that reduce the content of mobile aluminium compounds and ensure
environmental safety and high productivity of agrocenoses on Albic Pantostagnic Luvisol. The
research was carried out in a long-term stationary experiment established in 1965 with different
doses of mineral fertilisers, manure and lime on an Albic Stagnic Luvisol. It was found that with
a prolonged application of mineral fertilisers and the use of this soil without fertilisers, the content
of mobile aluminium compounds at the end of the X rotation at pHKCl 4.20 and 4.42 was 68.4 and
58.5 mg kg-1 respectively. Under the organo-mineral and mineral fertilisation systems with
liming with 6.0 t ha-1 of CaCO3 calculated by hydrolytic acidity, the content of mobile aluminium
compounds decreased to 7.2 and 6.7 mg kg-1 of soil respectively. Under identical fertilisation
systems with a lime application by pH-buffering capacity (2.5 t ha-1 CaCO3), the content of
mobile aluminium compounds is 10.8â10.0 mg kg-1 soil
Carbon dioxide emission and humus status of Albic Stagnic Luvisol under different fertilization regimes
The increase in the carbon dioxide content in the atmosphere, which enhances the greenhouse effect and leads to climate change, is the fundamental scientific problem of nowadays. Modern approaches to fertility management technologies of acid soils based on the principles of resource conservation and environmental safety are presented. They are based on the results of the study of carbon dioxide emission intensity, humus status, and crop rotation productivity in a classic long-term agricultural experiment under the influence of long-term use of various fertilizer systems with the application of ameliorant doses calculated by pH buffering capacity and hydrolytic acidity. The organo-mineral fertilizer system with the addition of 10 t of manure per ha of crop rotation area + N65P68K68, liming with a CaCO3 dose calculated according to pH buffering capacity (2.5 t/ha) contributes most to the optimization of soil processes. At the same time, it ensures the rational use of fertilizers and ameliorants, preservation of fertility, optimizes the processes of humus formation and carbon dioxide release. A high level of productivity of Albic Stagnic Luvisols forms under these conditions â 7.38 t/ha of grain units. Application of 1.0 and 1.5 lime norms calculated according to soil hydrolytic acidity with organic-mineral and mineral fertilizer systems on Albic Stagnic Luvisols in a short four-field crop rotation is not only a high-cost measure. However, it causes significant carbon loss in the form of CO2 due to additional mineralization. It is accompanied by calcium leaching and creates environmental problems in the conditions of the periodic washing-off water regime. Therefore, liming by CaCO3 dose calculated according to acid-base buffering capacity should be carried out before each of the following rotations in order to harmonize the environmental and productive functions of Albic Stagnic Luvisols in the short crop rotation. The obtained research results will be used to improve the methodology for determining carbon dioxide emissions and predicting the effect of various fertilizer and liming systems on its balance in the soil
Utilization of direct smears of thyroid fineâneedle aspirates for ancillary molecular testing: A comparison of two proprietary testing platforms
Background
Ancillary molecular testing has been recommended for thyroid fineâneedle aspirates (FNA) with indeterminate cytologic diagnoses. Rosetta Genomics and Interpace Diagnostics have developed assays that can utilize direct smears as the testing substrate.
Methods
A retrospective study of indeterminate thyroid FNAs with known histologic followâup was performed. One DiffâQuikâstained smear and one Papanicolaouâstained smear with similar cellularity (at least 60â100 lesional cells) from each case were sent to Rosetta and Interpace, respectively, for analysis. The results were directly compared and correlated with the final histopathology. Neither company was aware of the followâup histologic findings in these cases.
Results
A total of 10 thyroid FNAs were identified from our 2015 files. The cytologic diagnoses included follicular lesion of undetermined significance (FLUS, nâ=â5), follicular neoplasm/suspicious for follicular neoplasm (FN/SFN, nâ=â4), and suspicious for malignancy (SM, nâ=â1). Of the seven cases with benign histology, six smears were classified as benign by the RosettaGX microRNA classifier, and one case was designated as suspicious. Five cases were negative by both ThyGenX oncogene panel and ThyraMIR microRNA classifier. One case was negative by ThyGenX and positive on followâup ThyraMIR, and one case was positive for KRAS mutation and positive on ThyraMIR. Both the RosettaGX and ThyGenX/ThyraMIR tests demonstrated positive results for the three histologically malignant cases.
Conclusion
This study demonstrates that two molecular testing platforms performed equally well using our stained direct smears. Both molecular tests revealed a 100% negative predictive rate. RosettaGX showed a 75% positive predictive value in comparison to 60% for ThyGenX/ThyraMIR
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