4,362 research outputs found

    Spatial solitons under competing linear and nonlinear diffractions

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    We introduce a general model which augments the one-dimensional nonlinear Schr\"{o}dinger (NLS) equation by nonlinear-diffraction terms competing with the linear diffraction. The new terms contain two irreducible parameters and admit a Hamiltonian representation in a form natural for optical media. The equation serves as a model for spatial solitons near the supercollimation point in nonlinear photonic crystals. In the framework of this model, a detailed analysis of the fundamental solitary waves is reported, including the variational approximation (VA), exact analytical results, and systematic numerical computations. The Vakhitov-Kolokolov (VK) criterion is used to precisely predict the stability border for the solitons, which is found in an exact analytical form, along with the largest total power (norm) that the waves may possess. Past a critical point, collapse effects are observed, caused by suitable perturbations. Interactions between two identical parallel solitary beams are explored by dint of direct numerical simulations. It is found that in-phase solitons merge into robust or collapsing pulsons, depending on the strength of the nonlinear diffraction

    The effect of pictorial depth information on projected size judgments.

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    When full depth cues are available, size judgments are dominated by physical size. However, with reduced depth cues, size judgments are influenced less by physical size and more by projected size. By manipulating monocularly presented pictorial depth cues only, in this study we reduced depth cues further than had previous size judgment studies. Participants were presented monocularly with two shapes against a background of zero (control), one, two, or three pictorial depth cues. Each cue was added progressively in the following order: height in the visual field, linear perspective, and texture gradient. Participants made a same/different judgment regarding the projected size of the two shapes (i.e., ignoring any depth cues). As was expected, accuracy increased and response times decreased as the ratio between the projected size of the two shapes increased (range of projected size ratios, 1:1-1:5). In addition, with the exception of the larger size ratios (1:4 and 1:5), detection of projected size difference grew poorer as depth cues were added. One- and two-cue conditions had the most weighting in this performance decrement, with little weighting from the three-cue condition. We conclude that even minimal depth information is difficult to inhibit, which indicates that depth perception requires little focused attention

    Introduction to the special issue on reproducibility in neuroimaging

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    The last decade has seen increasing attention to the problem of scientific reproducibility, across a broad range of scientific fields (Camerer et al., 2016;Morrison, 2014;Open Science Collaboration, 2015). Within the field of neuroimaging, there has been a particular focus on issues of analytic variability (Bowring et al., 2019;Carp, 2012) statistical power (Button et al., 2013;Poldrack et al., 2017), and test-retest reliability (Bennett and Miller, 2013), all of which have raised alarms regarding the potential for irreproducible results. In addition, failed replications (Boekel et al., 2015;Dinga et al., 2019) and meta-analytic null results (Müller et al., 2017) have raised particular concern about studies of group and individual differences. This special issue was developed in light of these emerging concerns, with the goal of highlighting and encouraging work that aims to both quantify and improve the reproducibility of neuroimaging research. Here we provide a brief overview of the papers within this special issue

    Ultrashort pulses and short-pulse equations in (2+1)−(2+1)-dimensions

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    In this paper, we derive and study two versions of the short pulse equation (SPE) in (2+1)−(2+1)-dimensions. Using Maxwell's equations as a starting point, and suitable Kramers-Kronig formulas for the permittivity and permeability of the medium, which are relevant, e.g., to left-handed metamaterials and dielectric slab waveguides, we employ a multiple scales technique to obtain the relevant models. General properties of the resulting (2+1)(2+1)-dimensional SPEs, including fundamental conservation laws, as well as the Lagrangian and Hamiltonian structure and numerical simulations for one- and two-dimensional initial data, are presented. Ultrashort 1D breathers appear to be fairly robust, while rather general two-dimensional localized initial conditions are transformed into quasi-one-dimensional dispersing waveforms

    Traveling Wave Solutions in a Chain of Periodically Forced Coupled Nonlinear Oscillators

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    Motivated by earlier studies of artificial perceptions of light called phosphenes, we analyze traveling wave solutions in a chain of periodically forced coupled nonlinear oscillators modeling this phenomenon. We examine the discrete model problem in its co-traveling frame and systematically obtain the corresponding traveling waves in one spatial dimension. Direct numerical simulations as well as linear stability analysis are employed to reveal the parameter regions where the traveling waves are stable, and these waves are, in turn, connected to the standing waves analyzed in earlier work. We also consider a two-dimensional extension of the model and demonstrate the robust evolution and stability of planar fronts and annihilation of radial ones. Finally, we show that solutions that initially feature two symmetric fronts with bulged centers evolve in qualitative agreement with experimental observations of phosphenes

    Emergence of classicality in small number entangled systems

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    We show the transition from a fully quantized interaction to a semiclassical one in entangled small number quantum systems using the quantum trajectories approach. In particular, we simulate the microwave Ramsey zones used in Rydberg atom interferometry, filling in the gap between the strongly entangling Jaynes Cummings evolution and the semiclassical rotation of the atomic internal states. We also correlate the information flowing with leaking photons to the entanglement generation between cavity field and flying atom and detail the roles played by the strong dissipation and the external driving force in preserving atomic coherence through the interaction.Comment: 4 pages, 6 figure

    Bacterial Death Results from Mutations Made in Translocation Peptide of Leucyl-tRNA Synthetase

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    The family of aminoacyl-tRNA synthetases (aaRSs) ensures the fidelity of translation through providing a pool of correctly aminoacylated tRNA products that become incorporated by the ribosome. Leucyl-tRNA synthetase (LeuRS) has two functionally separate domains, one is the aminoacylation domain and the other is the CP1 editing domain. LeuRS can aminoacylate noncognate amino acids, therefore it relies on the CP1 editing domain to hydrolyze misaminoacylated tRNA products before they are released from the enzyme. The LeuRS enzyme must undergo a structural transition state in its reaction cycle in order to translocate the 3\u27 acceptor stem of tRNA 30 Ã… from the aminoacylation active site to the CP1 domain hydrolytic active site. The translocation event is difficult to study, but we believe that we have generated mutations within LeuRS that alter the translocation event of tRNA. The mutations that we have generated lead to bacterial death in Escherichia coli (E. coli). Circular dichorism experiments indicate that our mutations do not significantly alter the secondary structure of LeuRS. In vitro biochemical studies demonstrate that these mutations reduce the rates of aminoacylation and hydrolysis, while also displaying misaminoacylation activity. We attribute these biochemical findings to the resulting bacterial death that is caused by these mutation

    Bacterial Death Results from Mutations Made in Translocation Peptide of Leucyl-tRNA Synthetase

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    The family of aminoacyl-tRNA synthetases (aaRSs) ensures the fidelity of translation through providing a pool of correctly aminoacylated tRNA products that become incorporated by the ribosome. Leucyl-tRNA synthetase (LeuRS) has two functionally separate domains, one is the aminoacylation domain and the other is the CP1 editing domain. LeuRS can aminoacylate noncognate amino acids, therefore it relies on the CP1 editing domain to hydrolyze misaminoacylated tRNA products before they are released from the enzyme. The LeuRS enzyme must undergo a structural transition state in its reaction cycle in order to translocate the 3\u27 acceptor stem of tRNA 30 Ã… from the aminoacylation active site to the CP1 domain hydrolytic active site. The translocation event is difficult to study, but we believe that we have generated mutations within LeuRS that alter the translocation event of tRNA. The mutations that we have generated lead to bacterial death in Escherichia coli (E. coli). Circular dichorism experiments indicate that our mutations do not significantly alter the secondary structure of LeuRS. In vitro biochemical studies demonstrate that these mutations reduce the rates of aminoacylation and hydrolysis, while also displaying misaminoacylation activity. We attribute these biochemical findings to the resulting bacterial death that is caused by these mutation

    Energetic particles observed by ISEE-1 and ISEE-2 in a cusp diamagnetic cavity on 29 September 1978

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    International audienceObservations by the ISEE-1 and ISEE-2 spacecraft on 29 September 1978 show large CEP (Cusp Energetic Particle) fluxes while passing through the dayside magnetospheric cusp in near coincident orbits. The event was observed around 11:00 MLT between roughly 12:30 and 13:00 UT by ISEE-1 and 12:00 and 13:00 UT by ISEE-2. During these periods, both electron and ion fluxes increased by more than two orders of magnitude, with the electron flux showing a strong peak at a pitch angle of 90°. The solar wind was ~710 km s?1 and the Dst was ~?200 nT, suggesting the occurrence of a strong geomagnetic storm. The ISEE-1 and ISEE-2 observations, however, show no time-energy dispersion of the CEPs, leading us to believe that these particles could not be the result of substorm processes in the magnetotail. The local magnetic field was depressed and extremely turbulent. Changes in the magnitude of the magnetic field anticorrelate closely to variations of the electron flux. The observations in electron flux peaking at 90° and the close anticorrelation between the local magnetic field strength and electron flux are unique and provide evidence of a potential local source for these energetic particles

    Mortality and Morbidity Following Endovascular Repair of Abdominal Aortic Aneurysms: Analysis of Two Single Centre Experiences

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    AbstractObjective to show how differences in anatomical and physiological risk factors can affect the outcome of endovascular repair of AAA by describing the experience of two centres with different selection policies. Methods one hundred and thirty-five patients (group I) were treated at Queen's Medical Centre (Nottingham, U.K.) using 101 in-house made and 34 manufactured stent-grafts. Median diameter, length and angulation of the proximal aneurysm neck were 26 mm, 27 mm, 40°, respectively. Seventy-six patients had ischaemic heart disease, 47 had left ventricular failure, median forced expiratory volume in one second (FEV1) was 83%, median creatinine was 100 μmol/l and median age was 72 years. Fifty patients (group II) were treated at Timone Hospital (Marseilles, France) using seven in-house made and 43 manufactured stent-grafts. Median diameter, length and angulation of the proximal aneurysm neck were 25 mm, 34 mm, 33°, respectively. Thirteen patients had ischaemic heart disease, two had left ventricular failure, median forced expiratory volume in one second was 101%, median creatinine was 108 μmol/l and mean age was 72 years. Results anatomical characteristics of the proximal neck were significantly worse in group I (p=0.02 for the three variables). Cardiac comorbidities were more frequent and mean FEV1 was lower in group I (p<0.0001 and p=0.001, respectively. Median aneurysm diameter was significantly greater in group I (65 mm) than in group II (53 mm) (p<0.001). Postoperative mortality was 9% and 0% in groups I and II respectively (p=0.03). The incidence of technical complications (groin wound complications and side branches endoleaks being excluded) was 20% and 0% in groups I and II, respectively (p=0.0006). Conclusion postoperative mortality and technical complication rates were significantly greater in group I than in group II, readily explained by poorer general condition and worse anatomical characteristics of the proximal neck in group I
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