64 research outputs found
Simulations of a micro-PET System based on Liquid Xenon
The imaging performance of a high-resolution preclinical microPET system
employing liquid xenon as the gamma ray detection medium was simulated. The
arrangement comprises a ring of detectors consisting of trapezoidal LXe time
projection ionization chambers and two arrays of large area avalanche
photodiodes for the measurement of ionization charge and scintillation light. A
key feature of the LXePET system is the ability to identify individual photon
interactions with high energy resolution and high spatial resolution in 3
dimensions and determine the correct interaction sequence using Compton
reconstruction algorithms. The simulated LXePET imaging performance was
evaluated by computing the noise equivalent count rate, the sensitivity and
point spread function for a point source, and by examining the image quality
using a micro-Derenzo phantom according to the NEMA-NU4 standard. Results of
these simulation studies included NECR peaking at 1326 kcps at 188 MBq (705
kcps at 184 MBq) for an energy window of 450 - 600 keV and a coincidence window
of 1 ns for mouse (rat) phantoms. The absolute sensitivity at the center of the
field of view was 12.6%. Radial, tangential, and axial resolutions of 22Na
point sources reconstructed with a list-mode maximum likelihood expectation
maximization algorithm were <= 0.8 mm (FWHM) throughout the field of view.
Hot-rod inserts of < 0.8 mm diameter were resolvable in the transaxial image of
a micro-Derenzo phantom. The simulations show that a liquid xenon system would
provide new capabilities for significantly enhancing PET images
Liquid Xenon Detectors for Positron Emission Tomography
PET is a functional imaging technique based on detection of annihilation
photons following beta decay producing positrons. In this paper, we present the
concept of a new PET system for preclinical applications consisting of a ring
of twelve time projection chambers filled with liquid xenon viewed by avalanche
photodiodes. Simultaneous measurement of ionization charge and scintillation
light leads to a significant improvement to spatial resolution, image quality,
and sensitivity. Simulated performance shows that an energy resolution of <10%
(FWHM) and a sensitivity of 15% are achievable. First tests with a prototype
TPC indicate position resolution <1 mm (FWHM).Comment: Paper presented at the International Nuclear Physics Conference,
Vancouver, Canada, 201
Nurse editor survey findings inform a white paper on student publication: Faculty and student resources
Often student submissions do not meet journal standards for scholarly writing and are not published. This session reviews writing resources in an evidence based White Paper on Student Publication. The session emphasizes concerns identified by editors related to student publications and helpful resources for faculty and students to address challenges
A review of the predictability and prediction of ENSO
A hierarchy of El Niño-Southern Oscillation (ENSO) prediction schemes has been developed during the Tropical Ocean-Global Atmosphere (TOGA) program which includes statistical schemes and physical models. The statistical models are, in general, based on linear statistical techniques and can be classified into models which use atmospheric (sea level pressure or surface wind) or oceanic (sea surface temperature or a measure of upper ocean heat content) quantities or a combination of oceanic and atmospheric quantities as predictors. The physical models consist of coupled ocean-atmosphere models of varying degrees of complexity, ranging from simplified coupled models of the “shallow water” type to coupled general circulation models. All models, statistical and physical, perform considerably better than the persistence forecast in predicting typical indices of ENSO on lead times of 6 to 12 months. The TOGA program can be regarded as a success from this perspective. However, despite the demonstrated predictability, little is known about ENSO predictability limits and the predictability of phenomena outside the tropical Pacific. Furthermore, the predictability of anomalous features known to be associated with ENSO (e.g., Indian monsoon and Sahel rainfall, southern African drought, and off-equatorial sea surface temperature) needs to be addressed in more detail. As well, the relative importance of different physical mechanisms (in the ocean or atmosphere) has yet to be established. A seasonal dependence in predictability is seen in many models, but the processes responsible for it are not fully understood, and its meaning is still a matter of scientific discussion. Likewise, a marked decadal variation in skill is observed, and the reasons for this are still under investigation. Finally, the different prediction models yield similar skills, although they are initialized quite differently. The reasons for these differences are also unclear
Neural transcriptome reveals molecular mechanisms for temporal control of vocalization across multiple timescales
TauFinder: A Reconstruction Algorithm for τ Leptons at Linear Colliders
An algorithm to find and reconstruct τ leptons was developed, which targets τs that produce high energetic, low multiplicity jets as can be observed at multi TeV e+e− collisions. However, it makes no assumption about the decay of the τ candidate thus finding hadronic as well as leptonic decays. The algorithm delivers a reconstructed τ as seen by the detector. This note provides an overview of the algorithm, the cuts used and gives some evaluation of the performance. A first implementation is available within the ILC software framework as a MAR- LIN processor . Appendix A is intended as a short user manual
Measurement of stau_1 pair production at CLIC
We present a study performed for the CLIC Conceptual Design Report Volume 3 on the measurement of stau_1 pair production at sqrt(s) = 1.4 TeV. Only the hadronic decay of taus are considered. Results obtained using full detector simulation and including beam-induced backgrounds for the mass and for the production cross section of the stau_1 are discussed
The CLIC ILD CDR Geometry for the CDR Monte Carlo Mass Production
The CLIC ILD CDR detector for the Monte Carlo event simulation is described in a GEANT4 application, with some parameters available in a database and XML files. This makes it difficult to quickly “look up” interesting parameters of the detector geometry used for the simulation. This note summarises the important geometrical parameters and some details of the implemented detector components
The CLIC SiD CDR Detector Model for the CLIC CDR Monte Carlo Mass Production
The CLIC SiD CDR detector model for full simulation using GEANT4 is presented in this note. It is used for the Monte Carlo mass production for the CLIC CDR. The CLIC SiD CDR detector model is based on the SiD detector concept developed for the ILC. This note is intended as a reference document for the geometry description, which is written in xml. All relevant numbers are presented in a comprehensive form and several illustrations are added to display the features of the detector model
Particle Flow Performance at CLIC
Particle Flow has been used very successfully in the studies for linear colliders. At CLIC with an energy of 3 TeV considerable machine background is present in the detector. Using timing cuts based on particle flow objects this background can be reduced significantly. A systematic study is carried out to understand the dependence of the jet energy resolution on the jet energy and angle. The performance of particle flow is evaluated based on the energy and mass resolution of W and Z particles in full simulation and reconstruction in the presence of background for both detector concepts considered for CLIC
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