A low complexity resource allocation algorithm for multicast service delivery in OFDMA networks

Allocating and managing radio resources to multicast transmissions in Orthogonal Frequency-Division Multiple Access (OFDMA) systems is the challenging research issue addressed by this paper. A subgrouping technique, which divides the subscribers into subgroups according to the experienced channel quality, is considered to overcome the throughput limitations of conventional multicast data delivery schemes. A low complexity algorithm, designed to work with different resource allocation strategies, is also proposed to reduce the computational complexity of the subgroup formation problem. Simulation results, carried out by considering the Long Term Evolution (LTE) system based on OFDMA, testify the effectiveness of the proposed solution, which achieves a near-optimal performance with a limited computational load for the system

Indirect Signatures of Type I See-Saw Scenarios

We consider the low energy constraints that can be applied to type I see-saw extensions of the Standard Model in which the right-handed neutrinos are taken at the electroweak scale. In the reported scenarios, the flavour structure of the charged current and neutral current weak interactions of the Standard Model leptons with the heavy right-handed neutrinos is essentially determined by the neutrino oscillation parameters. In this case, correlations among different measurable phenomena in the lepton sector may provide compelling indirect evidence of low energy see-saw mechanism of neutrino mass generation.Comment: 4 pages, 2 figures. Contributions to the Proceedings of the 12th International Conference on Topics in Astroparticle and Underground Physics (TAUP 2011), Munich, Germany, 5-9 September 201

The multiplicative effect of combining alcohol with energy drinks on adolescent gambling

Purpose: There has been increased concern about the negative effects of adolescents consuming a combination of alcohol mixed with energy drinks (AmED). To date, few studies have focused on AmED use and gambling. The present study analyzed the multiplicative effect of AmED consumption, compared to alcohol alone, on the likelihood of at-risk or problem gambling during adolescence. Methods: Data from the ESPAD®Italia 2015 study, a cross-sectional survey conducted in a nationally representative sample of students (ages 15 to 19 years) were used to examine the association between self-reported AmED use (≥ 6 times, ≥ 10 times, and ≥ 20 times during the last month) and self-reported gambling severity. Multivariate models were used to calculate adjusted prevalence ratios to evaluate the association between alcohol use, AmED use, and gambling among a representative sample of adolescents who reported gambling in the last year and completed a gambling severity scale (n = 4495). Results: Among the 19% students classed as at-risk and problem gamblers, 43.9% were classed as AmED consumers, while 23.6% were classed as alcohol consumers (i.e. did not mix alcohol with energy drinks). In multivariate analyses that controlled for covariates, AmED consumers were three times more likely to be at-risk and problem gamblers (OR = 3.05) compared to non-consuming adolescents, while the effect became less pronounced with considering those who consumed alcohol without the addition of energy drinks (OR = 1.37). Conclusions: The present study clearly established that consuming AmED might pose a significantly greater risk of experiencing gambling-related problems among adolescents

Disentangling meaning in the brain: Left temporal involvement in agreement processing

Published online 18 November 2016Sentence comprehension is successfully accomplished by means of a form-to-meaning mapping procedure that relies on the extraction of morphosyntactic information from the input and its mapping to higher-level semantic–discourse representations. In this study, we sought to determine whether neuroanatomically distinct brain regions are involved in the processing of different types of information contained in the propositional meaning of a sentence, namely person and number. While person information indexes the role that an individual has in discourse (i.e., the speaker, the addressee or the entity being talked about by speaker and addressee), number indicates its cardinality (i.e., a single entity vs a multitude of entities). An event-related functional magnetic resonance imaging (fMRI) experiment was run using agreement-Correct and Person- and Number-violated sentences in Spanish, to disentangle the processing mechanisms and neural substrates associated with the building of discourse and cardinality representations. The contrast between Person and Number Violations showed qualitative and quantitative differences. A greater response for person compared to number was found in the left middle temporal gyrus (LMTG). However, critically, a posterior-to-anterior functional gradient emerged within this region. While the posterior portion of the LMTG was sensitive to both Person and Number Violations, the anterior portion of this region showed selective response for Person Violations. These results confirm that the comprehension of the propositional meaning of a sentence results from a composite, feature-sensitive mechanism of form-to-meaning mapping in which the nodes of the language network are differentially involved.BCBL acknowledges funding from Ayuda Centro de Excelencia Severo Ochoa SEV-2015-0490. S.M. acknowledges funding from the Gipuzkoako Foru Aldundia Fellowship Program and from grant PI_2014_38 from the Basque Government. N.M. was funded by grant PSI2012- 32350 and PSI2015-65694-P from the Spanish Ministry of Economy and Competitiveness. M.C was funded by grant PSI2012-31448 from the Spanish Ministry of Science and Innovation and ERC-2011-ADG-295362 from the European Research Council

Profiling of Glycan Receptors for Minute Virus of Mice in Permissive Cell Lines Towards Understanding the Mechanism of Cell Recognition

The recognition of sialic acids by two strains of minute virus of mice (MVM), MVMp (prototype) and MVMi (immunosuppressive), is an essential requirement for successful infection. To understand the potential for recognition of different modifications of sialic acid by MVM, three types of capsids, virus-like particles, wild type empty (no DNA) capsids, and DNA packaged virions, were screened on a sialylated glycan microarray (SGM). Both viruses demonstrated a preference for binding to 9-O-methylated sialic acid derivatives, while MVMp showed additional binding to 9-O-acetylated and 9-O-lactoylated sialic acid derivatives, indicating recognition differences. The glycans recognized contained a type-2 Galβ1-4GlcNAc motif (Neu5Acα2-3Galβ1-4GlcNAc or 3′SIA-LN) and were biantennary complex-type N-glycans with the exception of one. To correlate the recognition of the 3′SIA-LN glycan motif as well as the biantennary structures to their natural expression in cell lines permissive for MVMp, MVMi, or both strains, the N- and O-glycans, and polar glycolipids present in three cell lines used for in vitro studies, A9 fibroblasts, EL4 T lymphocytes, and the SV40 transformed NB324K cells, were analyzed by MALDI-TOF/TOF mass spectrometry. The cells showed an abundance of the sialylated glycan motifs recognized by the viruses in the SGM and previous glycan microarrays supporting their role in cellular recognition by MVM. Significantly, the NB324K showed fucosylation at the non-reducing end of their biantennary glycans, suggesting that recognition of these cells is possibly mediated by the Lewis X motif as in 3′SIA-LeX identified in a previous glycan microarray screen