1,563 research outputs found

    Philosophy, execution and efficacy of the guidance system as seen through Edinburgh schools

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    In this paper I wish to discuss the Scottish Guidance System: its birth and early development, its theory and its practice as seen through a sample of Edinburgh Secondary Schools and comment on its possible future.The scope of this kind of analysis is quite enormous and I only scratch the surface. A more detailed survey will need to be done if effective assessment of the current situation is to be made for the whole of Scotland.While developing this paper over the past three years I have found that my own attitudes have changed with regard to the objectives and relative merits of this system called Guidance, This I feel is healthy and I am sure the System can stand all the twists and contortions placed upon it. It is a dynamic area dealing with people in their own unique situations requiring unique assessments and solutions. As it develops as an ongoing enterprise it gains in confidence, makes mistakes, assesses and re- assesses, growing in promise each year. Can it fulfil all that it promises? I hope that this survey in some way shows how Edinburgh Schools are responding

    Relationship quality and men\u27s oxidative stress

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    The association between oxidative stress and quality of romantic relationships was investigated in a sample of 98 college males. Given a postulated life history trade-off between current and future reproductive potential, men currently in higher quality romantic relationships may expend less general mating effort (i.e., less energy allocation to finding, attracting, and competing for new mates) than single men or men in lesser quality relationships. Reduced mating effort may allow greater allocation of energy to anti-oxidant defense systems, and increased resistance to oxidative damage by reactive oxygen species (ROS). Consistent with this prediction, men who reported being in higher quality romantic relationships (i.e., relationships characterized by greater mutual investment and emotional engagement) had significantly lower levels of oxidative stress than men lacking such relationships. Neither testosterone nor cortisol mediated the effect. Due to the correlational nature of the research design, causal relations are unclear; theoretical interpretations are discussed. Resistance to oxidative damage could be a physiological mechanism by which the experience of being in a higher quality romantic relationship manifests in direct health benefits. Alternatively, men with inherently greater resistance to oxidative damage (due to less ROS production, better functioning anti-oxidant defense, or both) may be more likely to achieve such relationships, owing to pre-existing superior quality or fitness

    A Wii Bit of Fun: A Novel Platform to Deliver Effective Balance Training to Older Adults

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    BACKGROUND: Falls and fall-related injuries are symptomatic of an aging population. This study aimed to design, develop, and deliver a novel method of balance training, using an interactive game-based system to promote engagement, with the inclusion of older adults at both high and low risk of experiencing a fall.STUDY DESIGN: Eighty-two older adults (65 years of age and older) were recruited from sheltered accommodation and local activity groups. Forty volunteers were randomly selected and received 5 weeks of balance game training (5 males, 35 females; mean, 77.18 ± 6.59 years), whereas the remaining control participants recorded levels of physical activity (20 males, 22 females; mean, 76.62 ± 7.28 years). The effect of balance game training was measured on levels of functional balance and balance confidence in individuals with and without quantifiable balance impairments.RESULTS: Balance game training had a significant effect on levels of functional balance and balance confidence (P Peer reviewedFinal Published versio

    DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes

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    There is some interest in how mammalian oocytes respond to different types of DNA damage because of the increasing expectation of fertility preservation in women undergoing chemotherapy. Double strand breaks (DSBs) induced by ionizing radiation and agents such as neocarzinostatin (NCS), and interstrand crosslinks (ICLs) induced by alkylating agents such as mitomycin C (MMC), are toxic DNA lesions that need to be repaired for cell survival. Here we examined the effects of NCS and MMC treatment on oocytes collected from antral follicles in mice, because potentially such oocytes are readily collected from ovaries and do not need to be in vitro grown to achieve meiotic competency. We found that oocytes were sensitive to NCS, such that this ionizing radiation mimetic blocked meiosis I and caused fragmented DNA. In contrast, MMC had no impact on the completion of either meiosis I or II, even at extremely high doses. However, oocytes treated with MMC did show ?-H2AX foci and following their in vitro maturation and parthenogenetic activation the development of the subsequent embryos was severely compromised. Addition of MMC to 1-cell embryos caused a similarly poor level of development, demonstrating oocytes have eventual sensitivity to this ICL-inducing agent but this does not occur during their meiotic division. In oocytes, the association of Fanconi Anemia protein, FANCD2, with sites of ICL lesions was not apparent until entry into the embryonic cell cycle. In conclusion, meiotic maturation of oocytes is sensitive to DSBs but not ICLs. The ability of oocytes to tolerate severe ICL damage and yet complete meiosis, means that this type of DNA lesion goes unrepaired in oocytes but impacts on subsequent embryo quality

    Program for computing partial pressures from residual gas analyzer data

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    A computer program for determining the partial pressures of various gases from residual-gas-analyzer data is given. The analysis of the ion currents of 18 m/e spectrometer peaks allows the determination of 12 gases simultaneously. Comparison is made to ion-gage readings along with certain other control information. The output data are presented in both tabular and graphical form

    Investigation of instability, dynamic forces, and effect of dynamic loading on strength of cages for the bearings in the high pressure oxygen turbopumps for the space shuttle main engine

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    Experiments were performed to determine the effect of cyclic loading on bearing cage strength. A long term working tensile load of approximately 1300 N (300 lbs) was found to be the likely maximum. Higher loads caused a decrease in cage tensile strength after the 125,000 cycle testing period. Poisson's ratio in compression was found to be highly dependent upon the direction of the fiberglass plies. At room temperature the value was 0.15 with the plies and 0.68 across the plies. At -196 C (-321 F), the value with the plies was 0.20. The results of the analyses conducted have again demonstrated the critical need for improved lubrication in the high pressure oxygen turbopump bearings. Lubricant films with low shear strength and low friction coefficients promote cage stability and decrease ball/cage forces during marginal operating conditions. The analysis of the effect of combined bearing loads on ball/cage loads has identified a radial load of 3600 N (800 lbs) as the maximum for the current clearance of the balls and cage pockets. Liquid oxygen impinging on the cage in the direction of rotation was found to enhance cage stability

    Effect of forward motion on engine noise

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    Methods used to determine a procedure for correcting static engine data for the effects of forward motion are described. Data were analyzed from airplane flyover and static-engine tests with a JT8D-109 low-bypass-ratio turbofan engine installed on a DC-9-30, with a CF6-6D high-bypass-ratio turbofan engine installed on a DC-10-10, and with a JT9D-59A high-bypass-ratio turbofan engine installed on a DC-10-40. The observed differences between the static and the flyover data bases are discussed in terms of noise generation, convective amplification, atmospheric propagation, and engine installation. The results indicate that each noise source must be adjusted separately for forward-motion and installation effects and then projected to flight conditions as a function of source-path angle, directivity angle, and acoustic range relative to the microphones on the ground

    Back-reacted saponite in Jurassic mudstones and limestones intruded by a Tertiary sill, Isle of Skye

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    The Lón Ostatoin stream section, Trotternish Peninsula, Isle of Skye, exposes a sequence of Middle Jurassic mudstones and limestones which have been locally metasomatized by a transgressive sill of Tertiary age. Limestones in the sequence, including some previously reported as bentonite, have been altered to an unusual assemblage of grossular garnet and saponite clay. The mudstones also contain large proportions of saponite together with pyroxene and zeolites. Saponite also occurs within the basalt intrusion. Grossular and pyroxene represent artifacts of relatively high-temperature assemblages that formed during an early phase of alteration. As the intrusion and adjacent altered country rocks cooled, lower-temperature fluids flowed through a late set of contraction (micro)fractures. Back-reacted saponite, analcime and clinoptilolite were formed, possibly as alteration products of the unstable higher-temperature minerals. The lower-temperature mineral assemblage eventually sealed the late fracture system. This paper highlights an important concept for the study of analogue sites used to investigate thermal effects on engineered liners or barrier host rocks for the landfill and radioactive-waste industries. This is that the original thermally altered mineral assemblage may be overprinted by later, lower-temperature back-reactions. A detailed understanding of both processes is necessary in order to construct a sensible model for the thermal and mineralogical evolution of the site

    Product stewardship in the composites industry

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    The definition and purpose of Product Stewardship is discussed. Its' impact in the composites industry is stated. The report also outlines 12 ways that Product Stewardship can be utilized by consumers
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