Achieving Profitability in Global Small Business Supply Chain Management

Supply chain managers of small and medium-sized enterprises face cost inefficiencies in meeting human, physical, and technology capital requirements. Small and medium-sized enterprise supply chain managers who fail to implement cost-efficiency strategies risk jeopardizing profitability. Grounded in the chaos theory, the purpose of this qualitative single case study was to explore the successful strategies SME supply chain managers used to create cost efficiencies to remain profitable. Participants were 3 corporate supply chain managers of a small and medium-sized international enterprise located in central Florida who were successful at creating cost efficiencies to remain profitable. The data collection process included face-to-face interviews, a review of documentation, and physical artifacts. Thematic analysis was used to analyze the data with 4 themes emerging to include leadership and organizational culture, visibility, policies and processes, and production and product sourcing. A key recommendation is that leaders fully embrace and work with department managers to implement strategies that integrate the development of all departments to ensure total organizational success. When small and medium-sized enterprises prosper, community economic conditions thrive, changing lives, homes, individuals, and communities

Factors in Mobile Game Design

Mobile is the fastest growing area for computer gaming. Fueled by the every growing sales of handheld devices, the increasing comfort of gamers with their devices, larger screens and availability of casual games, mobile games offer the developer an area of rapid growth. In this paper we report on the commencement of research that attempts to identify the key development concepts for a mobile game. Gamers’ locus of controlis examined to determine the extent to which this personality trait impacts both interest level and type of game. We consider two mobile games, Grand Theft Auto and Edge, in an attempt to isolate the important design characteristics for this medium

Effects of Free Molecular Heating on the Space Shuttle Active Thermal Control System

During Space Transportation System (STS) flight 121, higher than predicted radiator outlet temperatures were experienced from post insertion and up until nominal correction (NC) burn two. Effects from the higher than predicted heat loads on the radiator panels led to an additional 50 lbm of supply water consumed by the Flash Evaporator System (FES). Post-flight analysis and research revealed that the additional heat loads were due to Free Molecular Heating (FMH) on the radiator panels, which previously had not been considered as a significant environmental factor for the Space Shuttle radiators. The current Orbiter radiator heat flux models were adapted to incorporate the effects of FMH in addition to solar, earth infrared and albedo sources. Previous STS flights were also examined to find additional flight data on the FMH environment. Results of the model were compared to flight data and verified against results generated by the National Aeronautics and Space Administration (NASA), Johnson Space Center (JSC) Aero-sciences group to verify the accuracy of the model

Full-Scale Wind-Tunnel Tests of Blowing Boundary-Layer Control Applied to a Helicopter Rotor

A full-scale wind-tunnel test was conducted of two boundary-layer-control applications to a 44-foot diameter helicopter rotor. Blowing from a nozzle near the leading edge of the blades delayed retreating blade stall. Results also indicated that delay of retreating blade stall could be obtained by cyclic blowing with a lower flow rate than that required for continuous blowing. It was found that blowing applied through a nozzle at mid-chord had no effect on retreating blade stall

Jet Bundles in Quantum Field Theory: The BRST-BV method

The geometric interpretation of the Batalin-Vilkovisky antibracket as the Schouten bracket of functional multivectors is examined in detail. The identification is achieved by the process of repeated contraction of even functional multivectors with fermionic functional 1-forms. The classical master equation may then be considered as a generalisation of the Jacobi identity for Poisson brackets, and the cohomology of a nilpotent even functional multivector is identified with the BRST cohomology. As an example, the BRST-BV formulation of gauge fixing in theories with gauge symmetries is reformulated in the jet bundle formalism. (Hopefully this version will be TeXable)Comment: 26 page

Gravity-driven instability in a spherical Hele-Shaw cell

A pair of concentric spheres separated by a small gap form a spherical Hele-Shaw cell. In this cell an interfacial instability arises when two immiscible fluids flow. We derive the equation of motion for the interface perturbation amplitudes, including both pressure and gravity drivings, using a mode coupling approach. Linear stability analysis shows that mode growth rates depend upon interface perimeter and gravitational force. Mode coupling analysis reveals the formation of fingering structures presenting a tendency toward finger tip-sharpening.Comment: 13 pages, 4 ps figures, RevTex, to appear in Physical Review

Mode-coupling approach to non-Newtonian Hele-Shaw flow

The Saffman-Taylor viscous fingering problem is investigated for the displacement of a non-Newtonian fluid by a Newtonian one in a radial Hele-Shaw cell. We execute a mode-coupling approach to the problem and examine the morphology of the fluid-fluid interface in the weak shear limit. A differential equation describing the early nonlinear evolution of the interface modes is derived in detail. Owing to vorticity arising from our modified Darcy's law, we introduce a vector potential for the velocity in contrast to the conventional scalar potential. Our analytical results address how mode-coupling dynamics relates to tip-splitting and side branching in both shear thinning and shear thickening cases. The development of non-Newtonian interfacial patterns in rectangular Hele-Shaw cells is also analyzed.Comment: 14 pages, 5 ps figures, Revtex4, accepted for publication in Phys. Rev.

Scaling Relations of Viscous Fingers in Anisotropic Hele-Shaw Cells

Viscous fingers in a channel with surface tension anisotropy are numerically studied. Scaling relations between the tip velocity v, the tip radius and the pressure gradient are investigated for two kinds of boundary conditions of pressure, when v is sufficiently large. The power-law relations for the anisotropic viscous fingers are compared with two-dimensional dendritic growth. The exponents of the power-law relations are theoretically evaluated.Comment: 5 pages, 4 figure

A phase 2, double-blind, multicenter, randomized, placebo-controlled, dose‑ranging study of the efficacy and safety of Astodrimer Gel for the treatment of bacterial vaginosis

Background Astodrimer Gel contains a novel dendrimer intended to treat and prevent bacterial vaginosis. We assessed the efficacy and safety of Astodrimer Gel for treatment of bacterial vaginosis. Methods 132 women with bacterial vaginosis were randomized 1:1:1:1 to Astodrimer 0.5% (N = 34), 1% (N = 33), or 3% (N = 32) Gel or hydroxyethyl cellulose placebo gel (N = 33) at a dose of 5 g vaginally once daily for 7 days at 6 centers in the United States. The primary endpoint was clinical cure (no bacterial vaginosis vaginal discharge and no more than one of 1) vaginal pH ≥4.5; 2) ≥20% clue cells; or 3) positive whiff test) at study days 21–30. Secondary analyses included clinical cure at study days 9–12, patient-reported symptoms, acceptability and adverse events. Results The Astodrimer 1% Gel dose was superior to placebo for the primary and selected secondary efficacy measures in the modified intent-to-treat population. Clinical cure rates at day 9–12 were superior to placebo for the Astodrimer 3%, 1% and 0.5% Gel groups (62.5% [15/24; P = .002], 74.1% [20/27; P < .001], and 55.2% [16/29; P = .001], respectively, vs. 22.2% [6/27]). At day 21–30, clinical cure rates were 46.2% (12/26) for the 1% dose vs. 11.5% for placebo (3/26; P = .006). A greater proportion of patients reported absence of vaginal discharge and vaginal odor at day 9–12 and day 21–30 for Astodrimer Gel groups compared with placebo. Adverse events considered potentially treatment-related occurred in only 25% of Astodrimer Gel-treated patients vs. 22% of placebo patients. Conclusion Astodrimer Gel once daily for 7 days was superior to placebo for treatment of bacterial vaginosis and was well-tolerated. The 1% dose consistently showed the strongest efficacy across endpoints. These results support a role for Astodrimer Gel, 1%, as an effective treatment for bacterial vaginosis