Three-dimensional flows in slowly-varying planar geometries

We consider laminar flow in channels constrained geometrically to remain between two parallel planes; this geometry is typical of microchannels obtained with a single step by current microfabrication techniques. For pressure-driven Stokes flow in this geometry and assuming that the channel dimensions change slowly in the streamwise direction, we show that the velocity component perpendicular to the constraint plane cannot be zero unless the channel has both constant curvature and constant cross-sectional width. This result implies that it is, in principle, possible to design "planar mixers", i.e. passive mixers for channels that are constrained to lie in a flat layer using only streamwise variations of their in-plane dimensions. Numerical results are presented for the case of a channel with sinusoidally varying width

Precision Drift Chambers for the Atlas Muon Spectrometer

ATLAS is a detector under construction to explore the physics at the Large Hadron Collider at CERN. It has a muon spectrometer with an excellent momentum resolution of 3-10%, provided by three layers of precision monitored-drift-tube chambers in a toroidal magnetic field. A single drift tube measures a track point with a mean resolution close to 100 micron, even at the expected high neutron and gamma background rates. The tubes are positioned within the chamber with an accuracy of 20 microns, achieved by elaborate construction and assembly monitoring procedures.Comment: 3 pages, 2 eps figures, Proceedings for poster at Physics in Collisions Conference (PIC03), Zeuthen, Germany, June 2003. FRAP1

Magnetic Response of Magnetospirillum Gryphiswaldense

In this study we modelled and measured the U-turn trajectories of individual magnetotactic bacteria under the application of rotating magnetic fields, ranging in ampitude from 1 to 12 mT. The model is based on the balance between rotational drag and magnetic torque. For accurate verification of this model, bacteria were observed inside 5 m tall microfluidic channels, so that they remained in focus during the entire trajectory. From the analysis of hundreds of trajectories and accurate measurements of bacteria and magnetosome chain dimensions, we confirmed that the model is correct within measurement error. The resulting average rate of rotation of Magnetospirillum Gryphiswaldense is 0.74 +- 0.03 rad/mTs.Comment: 17 pages, 12 figure

Economic literacy and inflation expectations: Evidence from a laboratory experiment

We present new experimental evidence on heterogeneity in the formation of inflation expectations and relate the variation to economic literacy and demographics. The experimental design allows us to investigate two channels through which expectations-formation may vary across individuals: (1) the choice of information and (2) the use of given information. Subjects who are more economically literate perform better along both dimensions - they choose more-relevant information and make better use of given information. Compared with survey data on inflation expectations, fewer demographic factors are associated with variation in inflation expectations, and economic literacy in most cases accounts for demographic variation in expectations

Large-Scale Production of Monitored Drift Tube Chambers for the ATLAS Muon Spectrometer

Precision drift tube chambers with a sense wire positioning accuracy of better than 20 microns are under construction for the ATLAS muon spectrometer. 70% of the 88 large chambers for the outermost layer of the central part of the spectrometer have been assembled. Measurements during chamber construction of the positions of the sense wires and of the sensors for the optical alignment monitoring system demonstrate that the requirements for the mechanical precision of the chambers are fulfilled

The role of the mobile proton in fucose migration

Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent experiments show that the rearrangement can also occur in intact glycan ions. These results suggest a low-energy barrier for migration of the fucose residue and broaden the relevance of fucose migration to include other types of mass spectrometry experiments, including ion mobility-mass spectrometry and ion spectroscopy. In this work, we utilize cold-ion infrared spectroscopy to provide further insight into glycan scrambling in intact glycan ions. Our results show that the mobility of the proton is a prerequisite for the migration reaction. For the prototypical fucosylated glycans Lewis x and blood group antigen H-2, the formation of adduct ions or the addition of functional groups with variable proton affinity yields significant differences in the infrared spectra. These changes correlate well with the promotion or inhibition of fucose migration through the presence or absence of a mobile proton

Nanoliter-sized overheated reactor

We report on a microfluidic system formed by 200 nl water droplets, encapsulated by a 600 nl mineral oil placed on a hydrophobically coated glass microscope cover slip. The micromachined heater underneath the glass was able to heat up the sample at a heating rate of 650 °C/s, heating the water sample up to 200 °C in less than 2 s. The sample/glass and the sample/oil interface did not have nucleation centers, showing that the sample reached a superheated stage without the necessity of being pressurized to suppress boiling. This method can be utilized for various applications currently being conducted in autoclaves.Web of Science1062art. no. 02410