Características mineraloquímicas e implicancias genéticas de la Vesubianita del Skarn Loma Marcelo, sierras australes de Buenos Aires

Fil: Ballivián Justiniano, Carlos A.. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Lajoinie, María Florencia. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Lanfranchini, Mabel Elena. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: de Barrio, Raúl Ernesto. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Canafoglia, María Elena. Centro de Química Inorgánica (CEQUINOR). Facultad de Ciencias Exactas. Universidad Nacional de La Plata; Argentin

Diques básicos en la Isla Martín García, provincia de Buenos Aires, Argentina

Basic dykes in the Martín García Island, Buenos Aires Province, Argentina. Basic dykes have been found emplaced in the igneous-metamorphic basement of the Martín García Island. The aim of this work is to provide preliminary geological-geochemical features of these dykes and to establish a comparison with those emplaced in the Tandilia System

Geología de un cuerpo cuarzoso en el área de la Estación Pablo Acosta, partido de Azul, basamento del Sistema de Tandilia

Among the several outcrops of the mainly Palaeoproterozoic igneous-metamorphic basement of the Tandilia System exposed near the Estación Pablo Acosta, a quartz body, associated to a NE-SO shear zone, was identified. Field work, petrologic and geochemical studies revealed that it was formed from a siliceous fluid generated by metamorphic differentiation during the Transamazonian orogeny. On the other hand, the high degree of quartz purity together with the estimated outcropping volume points out a potential importance for industrial commercialization of the mineralization. In addition, this research provides valuable information to the geological-genetic model for the Tandilia System of the Buenos Aires Province

Faja milonítica El Cortijo: puesta en valor de su patrimonio geominero y propuesta de un nuevo sitio de interés geológico en Tandil, Buenos Aires

El basamento del Sistema de Tandilia reúne a las rocas más antiguas de la Argentina, las cuales guardan una valiosa información de los procesos geológicos ocurridos hace aproximadamente 2.200 Ma. Entre estas rocas ígneo-metamórficas (Complejo Buenos Aires) se encuentran las que integran la Formación El Cortijo, que contrastan notoriamente con el resto por sus características mineralógicas, metamórficas y estructurales. Esta Formación está constituida por rocas típicas de una cuenca oceánica desarrollada durante el lapso Neoarqueano - Paleoproterozoico, fuertemente milonitizadas. Aflora en las cercanías de la ciudad de Tandil, a lo largo de una faja de 3 kilómetros con rumbo este-oeste (aquí denominada Faja milonítica El Cortijo), a la que se accede por la Ruta Nacional 226. Tandil es una ciudad reconocida por su origen minero, actualmente con una fuerte impronta turística y una infraestructura óptima para ofrecer diversos circuitos geomineros. Esta contribución tiene como objetivo presentar un nuevo sitio de interés geológico en Tandil, que junto con los otros circuitos geoturísticos urbanos, manifieste el valor geológico de la región. Esto conduciría a su protección y podría impulsar la creación de un futuro Parque Geológico, producto de la integración de todos los geositios conocidos además del aquí propuesto. El trabajo realizado incluyó un relevamiento del área mediante imágenes satelitales y actividades de campo que permitieron seleccionar un conjunto de canteras labradas en la faja milonítica que constituye el geositio propuesto. Este sector de la provincia de Buenos Aires reúne todos los atributos necesarios para establecer un sitio de interés geológico como el sugerido, considerando sus riquezas paisajísticas y geológicas relacionadas con la evolución geológica y tectónica del basamento de Tandilia

Current opinions and recommendations of paediatric healthcare professionals - The importance of tablets:Emerging orally disintegrating versus traditional tablets

The appropriate prescribing of paediatric dosage forms is paramount in providing the desired therapeutic effect alongside successful medication adherence with the paediatric population. Often it is the opinion of the healthcare practitioner that dictates which type of dosage form would be most appropriate for the paediatric patient, with liquids being both the most commonly available and most commonly used. Orally disintegrating tablets (ODTs) are an emerging dosage form which provide many benefits over traditional dosage forms for paediatric patients, such as rapid disintegration within the oral cavity, and the reduction in the risk of choking. However the opinion and professional use of healthcare practitioners regarding ODT's is not known. This study was designed to assess the opinions of several types of healthcare professionals (n = 41) regarding ODTs, using a survey across two hospital sites. Results reaffirmed the popularity of liquids for prescribing in paediatrics, with 58.0% of participants preferring this dosage form. ODTs emerged as the second most popular dosage form (30.0%), with healthcare practitioners indicating an increasing popularity amongst patients in the hospital setting, belief with 63.0% of practitioners agreeing that many liquid formulations could be substituted with a suitable ODT. The desired properties of an ideal ODT were also identified by healthcare practitioners preferring a small, fast disintegrating tablet (90.2% and 95.1% respectively), with the taste, disintegration time and flavour being the three most important attributes identified (29.5%, 28.7% and 21.7% respectively). This study provided a pragmatic approach in assessing healthcare professional's opinions on ODTs, highlighting the ideas and thoughts of practitioners who are on the frontline of paediatric prescribing and treatment and gave an indication to their preference for ODT properties

Solid oral forms availability in children: a cost saving investigation

AIM: To assess the suitability and potential cost savings, from both the hospital and community perspective, of prescribed oral liquid medicine substitution with acceptable solid forms for children over 2 years. METHOD: Oral liquid medicines dispensed from a paediatric hospital (UK) in 1 week were assessed by screening for existence of the solid form alternative and evaluating the acceptability of the available solid form, firstly related to the prescribed dose and secondly to acceptable size depending on the child's age. Costs were calculated based on providing treatment for 28 days or prescribed duration for short term treatments. RESULTS: Over 90% (440/476) of liquid formulations were available as a marketed solid form. Considering dosage acceptability (maximum of 10% deviation from prescribed dosage or 0% for narrow therapeutic range drugs, maximum tablet divisions into quarters) 80% of liquids could be substituted with a solid form. The main limitation for liquid substitution would be solid form size. However, two-thirds of prescribed liquids could have been substituted with a suitable solid form for dosage and size, with estimated savings being of £5K and £8K in 1 week, respectively based on hospital and community costs, corresponding to a projected annual saving of £238K and £410K (single institution). CONCLUSION: Whilst not all children over 2 years will be able to swallow tablets, drug cost savings if oral liquid formulations were substituted with suitable solid dosage forms would be considerable. Given the numerous advantages of solid forms compared with liquids, this study may provide a theoretical basis for investing in supporting children to swallow tablets/capsules