Adviesregel pootaardappelen 24 : een toets in de praktijk van de werking van stikstof bijbemesten op basis van gewasreflectie metingen in pootaardappelen

In Noord Nederland is de teelt van pootaardappelen een zeer belangrijk onderdeel binnen de bedrijfsvoering van verreweg de meeste akkerbouwbedrijven. Het spreekt dan ook voor zich dat er vanuit de telers belangstelling is voor nieuwe ontwikkelingen die het rendement van de pootgoedteelt verder kunnen verbeteren. Binnen het Programma PrecisieLandbouw (PPL) is er vanuit een aantal telersgroepen, te weten “de Wadden”, “Spinoff” en “het Hogeland” samen met mechanisatiebedijf Mijno van Dijk het verzoek aan PPO gedaan om een praktijkexperiment uit te voeren op een perceel aardappelen van pootgoedteler (en lid van Spinoff) Anselm Claassen

Ongoing Medical Management to Maximize Health and Well-being for Persons Living With Dementia

Background and Objectives: Persons living with dementia have complex care needs including memory loss that should be taken into account by providers and family caregivers involved with their care. The prevalence of comorbid conditions in people with dementia is high and, thus, how primary care, community providers and family caregivers provide best practice care, person-centered care is important. Research Design and Methods: Care providers should understand the ongoing medical management needs of persons living with dementia in order to maximize their quality of life, proactively plan for their anticipated needs, and be as well prepared as possible for health crises that may occur. Results: This article provides eight practice recommendations intended to promote understanding and support of the role of nonphysician care providers in educating family caregivers about ongoing medical management to improve the wellbeing of persons living with dementia. Discussion and Implications: Key among these are recommendations to use nonpharmacological interventions to manage behavioral and psychological symptoms of dementia as the first line of treatment and recommendations on how to best support the use and discontinuation of pharmacological interventions as necessary

A Systematic Review of Interventions to Improve the Communication of Advanced Directives and Medication Administration Records for Elderly Patients Transferring Between Nursing Homes and Acute Care Hospitals

Objectives: To conduct a systematic review of the literature to identify interventions that can improve the communication of advanced care directives and accurate and appropriate medication lists for elderly patients transferring between nursing homes and acute care hospitals. Methods: The MEDLINE, ISI, and EBSCO Host databases were searched from inception to February 17, 2008 for appropriate articles. All abstracts identified by a prespecified strategy were reviewed. Studies met inclusion criteria if their design was of a randomized control trial, pre/post observational trial, or post-intervention observational study. Data regarding each study were abstracted from the manuscript by the reviewer to a standardized collection instrument and details regarding type of study, study population, intervention, and results were recorded in evidence tables. Results: Six hundred ninety-six titles were identified by the pre-specified search strategies. Eighteen articles were submitted for full review. Thirteen articles did not meet inclusion/exclusion criteria and five articles were determined to describe interventions that resulted in the enhanced transition of appropriate medication lists or advanced directives between skilled nursing facilities and acute care hospital settings, whether to the emergency department or inpatient units. Of these articles, two articles described interventions that resulted in the enhanced transmission of advanced directives, two articles described interventions that resulted in the better transmission of medication lists, and one article described an intervention that accomplished both of these goals. Conclusions: The accurate communication of key patient information is integral to providing high quality health care to elderly, skilled nursing facility patients transferring to and from acute care hospitals. A standardized patient transfer document may assist with the successful communication of advanced care directives and medication lists, while a pharmacist-developed review of medication lists may help identify omitted or indicated medications on patient transfer. Randomized controlled trials with large number of patients in varied health care systems may be needed to determine the ideal design and medium for a patient transfer document. Further work will be needed to coordinate research efforts and adopt standardized definitions of high quality transitional care.Master of Public Healt

Mesenchymal/epithelial regulation of retinoic acid signaling in the olfactory placode

We asked whether mesenchymal/epithelial (M/E) interactions regulate retinoic acid (RA) signaling in the olfactory placode and whether this regulation is similar to that at other sites of induction, including the limbs, branchial arches, and heart. RA is produced by the mesenchyme at all sites, and subsets of mesenchymal cells express the RA synthetic enzyme RALDH2, independent of M/E interactions. In the placode, RA-producing mesenchyme is further distinguished by its coincidence with a molecularly distinct population of neural crest-associated cells. At all sites, expression of additional RA signaling molecules ( CRABP1) depends on M/E interactions. Of these molecules, RA regulates only , and this regulation depends on M/E interaction. Expression of and all of which are thought to influence RA signaling, is also regulated by M/E interactions independent of RA at all sites. Despite these common features, expression is distinct in the placode, as is regulation of and RALDH2 by Fgf8. Thus, M/E interactions regulate expression of RA receptors and cofactors in the olfactory placode and other inductive sites. Some aspects of regulation in the placode are distinct, perhaps reflecting unique roles for additional local signals in neuronal differentiation in the developing olfactory pathway

Mesenchymal/epithelial regulation of retinoic acid signaling in the olfactory placode

We asked whether mesenchymal/epithelial (M/E) interactions regulate retinoic acid (RA) signaling in the olfactory placode and whether this regulation is similar to that at other sites of induction, including the limbs, branchial arches, and heart. RA is produced by the mesenchyme at all sites, and subsets of mesenchymal cells express the RA synthetic enzyme RALDH2, independent of M/E interactions. In the placode, RA-producing mesenchyme is further distinguished by its coincidence with a molecularly distinct population of neural crest-associated cells. At all sites, expression of additional RA signaling molecules ( CRABP1) depends on M/E interactions. Of these molecules, RA regulates only , and this regulation depends on M/E interaction. Expression of and all of which are thought to influence RA signaling, is also regulated by M/E interactions independent of RA at all sites. Despite these common features, expression is distinct in the placode, as is regulation of and RALDH2 by Fgf8. Thus, M/E interactions regulate expression of RA receptors and cofactors in the olfactory placode and other inductive sites. Some aspects of regulation in the placode are distinct, perhaps reflecting unique roles for additional local signals in neuronal differentiation in the developing olfactory pathway

Risk factors for the progression of mild cognitive impairment to dementia

The increasing prevalence of cognitive impairment among the older adult population warrants attention to the identification of practices that may minimize the progression of early forms of cognitive impairment, including the transitional stage of mild cognitive impairment (MCI), to permanent stages of dementia. This article identifies both markers of disease progress and risk factors linked to the progression of MCI to dementia. Potentially modifiable risk factors may offer researchers a point of intervention to modify the effect of the risk factor and to minimize the future burden of dementia

Acceptability and Results of Dementia Screening Among Older Adults in the United States

OBJECTIVES: To measure older adults acceptability of dementia screening and assess screening test results of a racially diverse sample of older primary care patients in the United States. DESIGN: Cross-sectional study of primary care patients aged 65 and older. SETTING: Urban and suburban primary care clinics in Indianapolis, Indiana, in 2008 to 2009. PARTICIPANTS: Nine hundred fifty-four primary care patients without a documented diagnosis of dementia. MEASUREMENTS: Community Screening Instrument for Dementia, the Mini-Mental State Examination, and the Telephone Instrument for Cognitive Screening. RESULTS: Of the 954 study participants who consented to participate, 748 agreed to be screened for dementia and 206 refused screening. The overall response rate was 78.4%. The positive screen rate of the sample who agreed to screening was 10.2%. After adjusting for demographic differences the following characteristics were still associated with increased likelihood of screening positive for dementia: age, male sex, and lower education. Patients who believed that they had more memory problems than other people of their age were also more likely to screen positive for dementia. CONCLUSION: Age and perceived problems with memory are associated with screening positive for dementia in primary care