217 research outputs found

    The Association Between Coping Strategies, Resilience, and Flourishing Among Students at Large U.S. University During the COVID-19 Pandemic: A Mixed Methods Research Study

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    Background: Mental illness indicators increased among U.S. university students in recent years; COVID-19 associated disruptions presented additional mental health challenges for students. Aim: This research aimed to assess the relationship between coping strategies identified by university students and scores on resilience and flourishing scales and to identify additional themes that described student experiences during the COVID-19 pandemic. Methods: An online survey was administered to students at a large public Midwestern University. Quantitative data were assessed using nonparametric tests for association and qualitative data were analyzed using cycles of open coding. Results: Most of the 3,473 respondents were female (76.5%) and white (83.6%), with a mean age of 24.67 years (SD = 8.08). The most frequent coping strategy was physical activity participation (n = 712), followed by socializing (n = 507). The highest resilience and flourishing scores were associated with compliance to COVID-19 associated recommendations or spiritual activities. Qualitative themes included the value of focusing on controllable aspects, the need to be strong for others, and the experience of academic overload during transition to online learning. Conclusions: Universities should endeavor to provide ongoing availability of counseling during university disruptions. Universities might also consider proactive efforts to guide students toward proficiency in strategies that improve coping skills, including some that do not center around technology

    Erosion of trust in humanitarian agencies: what strategies might help?

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    Aid agencies (AAs) provide a range of humanitarian and health related assistance globally. However, the trust placed on them is eroding. Evidence for this includes accusations of a decline in their humanitarianism, and the increasing number of conflicts with host states. An analysis of the concerns expressed yields two possible reasons: a relative lack of transparency of their work and weak accountability mechanisms. This is further supported by the existing milieu: an absence of internationally accepted instrument or mechanism to check the credentials of INGOs and an opaque system of close links between some of the INGOs and their donors. The article suggests two global strategies to tackle these issues: (a) Increase transparency by establishing a global register of aid agencies. This should have basic information: their main goals and activities, countries they are active in, number of employees, annual turnover of funds (updated regularly), principal financing sources and nature of links with donors. This could also be available as printed manual that should be freely available to client countries. (b) Ensure accountability by developing templates of fair legal instruments (to facilitate and regulate work), and a set of generic rules and procedures of engagement for the interactions between agencies and client states. These should be institutionalized within the regulatory frameworks of countries and included in the Codes of Conduct of NGOs

    Effect of blanching treatments and dehydration methods on rehydration quality of khejri (Prosopis cineraria) pods

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    The khejri (Prosopis cineraria L. Druce), is a multipurpose leguminous tree of hot arid desert. Its tender pods are utilized for culinary purpose both in fresh and dehydrated conditions without ascertaining its quality aspect. Therefore, the present investigation was carried out to find out the effect of blanching treatments and dehydration methods on rehydration quality of khejri pods. The experiment consists of three methods of drying and six blanching treatments replicated thrice under completely randomised design (CRD). Both tender pods (harvested within 20 days of fruit set at green stage) and mature pods (harvested after 25 days of fruit set at colour turning stage) were taken for the study. Among various methods of drying; sun drying took minimum time (11 hours) while other methods took comparatively longer period for drying. Moreover, recovery per cent of pods did not vary significantly within the drying methods and blanching treatments. In general, tender pods recovery was less compared to matured pods. The rehydration ratio was maximum in pods blanched in hot water (5 min.) followed by control. Among different methods, the rehydration ratio was maximum in shade drying followed by sun drying and the least in tray drier. The storage life of dehydrated pods was more than 52 weeks in blanching treatment than only about 8 weeks in control (un-blanched pods). The appearance of sun dried pods was not good as brownish and grayish colour pods were observed. Whereas in case of pods dried in shade and tray drier were green in colour. The protein content was also higher in pods dehydrated either in shade or in tray drier but the differences among the blanching treatments were non-significant. Thus, it can be concluded that the tender pods dried after blanching in 2 per cent salt solution (5 min.) or blanched in 2 per cent salt solution (5 min.) + 0.1 per cent KMS (potassium metabisulphite) either in shade or in tray drier have overall good acceptability because of retention of green colour, higher protein content, good storage life, better appearance after rehydration, good culinary taste, overall higher hedonic rating and more hygienic conditions than open sun drying

    T cell receptor Vbeta gene usage in Thai children with dengue virus infection

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    T lymphocyte activation during dengue is thought to contribute to the pathogenesis of dengue hemorrhagic fever (DHF). We examined the T cell receptor Vbeta gene usage by a reverse transcriptase-polymerase chain reaction assay during infection and after recovery in 13 children with DHF and 13 children with dengue fever (DF). There was no deletion of specific Vbeta gene families. We detected significant expansions in usage of single Vbeta families in six subjects with DHF and three subjects with DF over the course of infection, but these did not show an association with clinical diagnosis, viral serotype, or HLA alleles. Differences in Vbeta gene usage between subjects with DHF and subjects with DF were of borderline significance. These data suggest that the differences in T cell activation in DHF and DF are quantitative rather than qualitative and that T cells are activated by conventional antigen(s) and not a viral superantigen

    Quasiparticle bandgap engineering of graphene and graphone on hexagonal boron nitride substrate

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    Graphene holds great promise for post-silicon electronics, however, it faces two main challenges: opening up a bandgap and finding a suitable substrate material. In principle, graphene on hexagonal boron nitride (hBN) substrate provides potential system to overcome these challenges. Recent theoretical and experimental studies have provided conflicting results: while theoretical studies suggested a possibility of a finite bandgap of graphene on hBN, recent experimental studies find no bandgap. Using the first-principles density functional method and the many-body perturbation theory, we have studied graphene on hBN substrate. A Bernal stacked graphene on hBN has a bandgap on the order of 0.1 eV, which disappears when graphene is misaligned with respect to hBN. The latter is the likely scenario in realistic devices. In contrast, if graphene supported on hBN is hydrogenated, the resulting system (graphone) exhibits bandgaps larger than 2.5 eV. While the bandgap opening in graphene/hBN is due to symmetry breaking and is vulnerable to slight perturbation such as misalignment, the graphone bandgap is due to chemical functionalization and is robust in the presence of misalignment. The bandgap of graphone reduces by about 1 eV when it is supported on hBN due to the polarization effects at the graphone/hBN interface. The band offsets at graphone/hBN interface indicate that hBN can be used not only as a substrate but also as a dielectric in the field effect devices employing graphone as a channel material. Our study could open up new way of bandgap engineering in graphene based nanostructures.Comment: 8 pages, 4 figures; Nano Letters, Publication Date (Web): Oct. 25 2011, http://pubs.acs.org/doi/abs/10.1021/nl202725

    SOCIO-PSYCHOLOGICAL STUDY AMONG INJECTABLE DRUG USERS IN KATHMANDU VALLEY

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    On the background of ever increasing HIV transmission in our community through various routes, the psychosocial factors related with intravenous drug abuse has become necessary to be studied. Aim of the study was to assess the Socio-psychological factors that influence people to use drugs, especially to use Injectable drugs. We enrolled a sample of 393 Intravenous drug users, all male, in the Kathmandu Valley. Participants were administered a semi structured proforma to assess the psychosocial issues related with the drug intravenous drug abuse. Mean age of the sample was 27.76+ 4.86 years. Majority were single, unemployed, Hindu and by caste Newars, with education more than high school (SLC or more). The first psychoactive substance use by most of them was cannabis. The most frequently used psychoactive substance was injection Buprenorphine (Tidigesic), which was followed by mixture of various substances (opiates, benzodiazepines, antihistamines) and Diacetyl morphine (Brown sugar). Factors associated with the start of the drugs were for enjoyment, friendā€™s pressure and to alleviate mental tension. Many accepted Injectable drug use contributing to problems in mental, marital, social, economic and legal aspects of their life. Despite knowing the harms caused by the drugs majority persist on its use. A needle exchange programme has been viewed positively by many. Key words: buprenorphin, needle sharing, needle replacement, HIV transmission

    A ferromagnetic Eu-Pt surface compound grown below hexagonal boron nitride

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    One of the fundamental applications for monolayer-thick 2D materials is their use as protective layers of metal surfaces and in situ intercalated reactive materials in ambient conditions. Here we investigate the structural, electronic, and magnetic properties, as well as the chemical stability in air of a very reactive metal, Europium, after intercalation between a hexagonal boron nitride (hBN) layer and a Pt substrate. We demonstrate that Eu intercalation leads to a hBN-covered ferromagnetic EuPt2 surface alloy with divalent Eu2+ atoms at the interface. We expose the system to ambient conditions and find a partial conservation of the di-valent signal and hence the Eu-Pt interface. The use of a curved Pt substrate allows us to explore the changes in the Eu valence state and the ambient pressure protection at different substrate planes. The interfacial EuPt2 surface alloy formation remains the same, but the resistance of the protecting hBN layer to ambient conditions is reduced, likely due to a rougher surface and a more discontinuous hBN coating

    Effect of Layer-Stacking on the Electronic Structure of Graphene Nanoribbons

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    The evolution of electronic structure of graphene nanoribbons (GNRs) as a function of the number of layers stacked together is investigated using \textit{ab initio} density functional theory (DFT) including interlayer van der Waals interactions. Multilayer armchair GNRs (AGNRs), similar to single-layer AGNRs, exhibit three classes of band gaps depending on their width. In zigzag GNRs (ZGNRs), the geometry relaxation resulting from interlayer interactions plays a crucial role in determining the magnetic polarization and the band structure. The antiferromagnetic (AF) interlayer coupling is more stable compared to the ferromagnetic (FM) interlayer coupling. ZGNRs with the AF in-layer and AF interlayer coupling have a finite band gap while ZGNRs with the FM in-layer and AF interlayer coupling do not have a band gap. The ground state of the bi-layer ZGNR is non-magnetic with a small but finite band gap. The magnetic ordering is less stable in multilayer ZGNRs compared to single-layer ZGNRs. The quasipartcle GW corrections are smaller for bilayer GNRs compared to single-layer GNRs because of the reduced Coulomb effects in bilayer GNRs compared to single-layer GNRs.Comment: 10 pages, 5 figure

    Cryptic Eimeria genotypes are common across the southern but not northern hemisphere

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    The phylum Apicomplexa includes parasites of medical, zoonotic and veterinary significance. Understanding the global distribution and genetic diversity of these protozoa is of fundamental importance for efficient, robust and long-lasting methods of control. Eimeria spp. cause intestinal coccidiosis in all major livestock animals and are the most important parasites of domestic chickens in terms of both economic impact and animal welfare. Despite having significant negative impacts on the efficiency of food production, many fundamental questions relating to the global distribution and genetic variation of Eimeria spp. remain largely unanswered. Here, we provide the broadest map yet of Eimeria occurrence for domestic chickens, confirming that all the known species (Eimeria acervulina, Eimeria brunetti, Eimeria maxima, Eimeria mitis, Eimeria necatrix, Eimeria praecox, Eimeria tenella) are present in all six continents where chickens are found (including 21 countries). Analysis of 248 internal transcribed spacer sequences derived from 17 countries provided evidence of possible allopatric diversity for species such as E. tenella (FST values ā©½0.34) but not E. acervulina and E. mitis, and highlighted a trend towards widespread genetic variance. We found that three genetic variants described previously only in Australia and southern Africa (operational taxonomic units x, y and z) have a wide distribution across the southern, but not the northern hemisphere. While the drivers for such a polarised distribution of these operational taxonomic unit genotypes remains unclear, the occurrence of genetically variant Eimeria may pose a risk to food security and animal welfare in Europe and North America should these parasites spread to the northern hemisphere

    Evidence that a positive feedback loop drives centrosome maturation in fly embryos.

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    Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn are thought to form a scaffold around the mother centriole that recruits other components of the mitotic PCM, and the Polo-dependent phosphorylation of Cnn at the centrosome is crucial for scaffold assembly. Here, we show that, like Cnn, Spd-2 is specifically phosphorylated at centrosomes. This phosphorylation appears to create multiple phosphorylated S-S/T(p) motifs that allow Spd-2 to recruit Polo to the expanding scaffold. If the ability of Spd-2 to recruit Polo is impaired, the scaffold is initially assembled around the mother centriole, but it cannot expand outwards, and centrosome maturation fails. Our findings suggest that interactions between Spd-2, Polo and Cnn form a positive feedback loop that drives the dramatic expansion of the mitotic PCM in fly embryos
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