330 research outputs found
Services of provincial irrigation offices to communal irrigation systems in Western Visayas, the Philippines
Irrigation management / Communal irrigation systems / Farmer-agency interactions / Maintenance / Farmers' associations / Institution building / Agricultural development / Training / Water distribution / Small-scale systems / Privatization / Philippines
Conjunctions of Among Constraints
Many existing global constraints can be encoded as a conjunction of among
constraints. An among constraint holds if the number of the variables in its
scope whose value belongs to a prespecified set, which we call its range, is
within some given bounds. It is known that domain filtering algorithms can
benefit from reasoning about the interaction of among constraints so that
values can be filtered out taking into consideration several among constraints
simultaneously. The present pa- per embarks into a systematic investigation on
the circumstances under which it is possible to obtain efficient and complete
domain filtering algorithms for conjunctions of among constraints. We start by
observing that restrictions on both the scope and the range of the among
constraints are necessary to obtain meaningful results. Then, we derive a
domain flow-based filtering algorithm and present several applications. In
particular, it is shown that the algorithm unifies and generalizes several
previous existing results.Comment: 15 pages plus appendi
Inter-individual variations of human mercury exposure biomarkers: a cross-sectional assessment
BACKGROUND: Biomarkers for mercury (Hg) exposure have frequently been used to assess exposure and risk in various groups of the general population. We have evaluated the most frequently used biomarkers and the physiology on which they are based, to explore the inter-individual variations and their suitability for exposure assessment. METHODS: Concentrations of total Hg (THg), inorganic Hg (IHg) and organic Hg (OHg, assumed to be methylmercury; MeHg) were determined in whole blood, red blood cells, plasma, hair and urine from Swedish men and women. An automated multiple injection cold vapour atomic fluorescence spectrophotometry analytical system for Hg analysis was developed, which provided high sensitivity, accuracy, and precision. The distribution of the various mercury forms in the different biological media was explored. RESULTS: About 90% of the mercury found in the red blood cells was in the form of MeHg with small inter-individual variations, and part of the IHg found in the red blood cells could be attributed to demethylated MeHg. THg in plasma was associated with both IHg and MeHg, with large inter-individual variations in the distribution between red blood cells and plasma. THg in hair reflects MeHg exposure at all exposure levels, and not IHg exposure. The small fraction of IHg in hair is most probably emanating from demethylated MeHg. The inter-individual variation in the blood to hair ratio was very large. The variability seemed to decrease with increasing OHg in blood, most probably due to more frequent fish consumption and thereby blood concentrations approaching steady state. THg in urine reflected IHg exposure, also at very low IHg exposure levels. CONCLUSION: The use of THg concentration in whole blood as a proxy for MeHg exposure will give rise to an overestimation of the MeHg exposure depending on the degree of IHg exposure, why speciation of mercury forms is needed. THg in RBC and hair are suitable proxies for MeHg exposure. Using THg concentration in plasma as a measure of IHg exposure can lead to significant exposure misclassification. THg in urine is a suitable proxy for IHg exposure
Biobehavioral research on nicotine use in women
More American women are taking up smoking than men and fewer are quitting; if current trends continue, rates for women will surpass those for men by the mid-1990's. But ironically, much of what is known about the biobehavioural aspects of smoking is based on research using male subjects. The present paper reviews evidence suggesting that: (1) women may differ from men with regard to nicotine intake and/or effects; (2) nicotine intake and effects may be influenced by menstrual cycle phase; (3) oral contraceptive use and estrogen replacement therapy may affect intake and effects of nicotine; (4) the effects of chronic nicotine use on female reproductive endocrinology may have implications for the reinforcement of smoking; and (5) pharmacological agents used to treat smoking may have different effects in women than in men. Guidelines and suggestions are presented by future biobehavioural research in women, including standardization of assessment procedures, attention to the use of appropriate controls, and use of pharmacological probes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73978/1/j.1360-0443.1991.tb01802.x.pd
Vegetation-based landscape regions of Hungary.
he first version of the map of the Hungarian vegetation-based landscape regions were prepared
at the scale of 1 : 200,000 (1 km or higher resolution). The primary goal of the map was
to provide an exact background for the presentation and evaluation of the data of theMÉTA
database. Secondly, we intended to give an up-to-date and detailed vegetation-based division
of Hungary with a comprehensive nomenclature of the regions. Regions were primarily defined on the basis of their present zonal vegetation, or their dominant extrazonal or
edaphic vegetation. Where this was not possible, abiotic factors that influence the potential
vegetation, the flora were taken into consideration, thus, political and economical factors
were ignored. All region borders were defined by local expert botanists, mainly based on
their field knowledge. The map differs in many features from the currently used, country-
wide, flora- or geography-based divisions in many features. We consider our map to be
temporary (i.e. a work map), and we plan to refine and improve it after 5 years of testing
Symptom patterns in women with premenstrual syndrome complaints: a prospective assessment using a marker for ovulation and screening criteria for adequate ovarian function
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72929/1/j.1365-2648.1991.tb01727.x.pd
Neonatal Administration of Thimerosal Causes Persistent Changes in Mu Opioid Receptors in the Rat Brain
Thimerosal added to some pediatric vaccines is suspected in pathogenesis of several neurodevelopmental disorders. Our previous study showed that thimerosal administered to suckling rats causes persistent, endogenous opioid-mediated hypoalgesia. Here we examined, using immunohistochemical staining technique, the density of μ-opioid receptors (MORs) in the brains of rats, which in the second postnatal week received four i.m. injections of thimerosal at doses 12, 240, 1,440 or 3,000 μg Hg/kg. The periaqueductal gray, caudate putamen and hippocampus were examined. Thimerosal administration caused dose-dependent statistically significant increase in MOR densities in the periaqueductal gray and caudate putamen, but decrease in the dentate gyrus, where it was accompanied by the presence of degenerating neurons and loss of synaptic vesicle marker (synaptophysin). These data document that exposure to thimerosal during early postnatal life produces lasting alterations in the densities of brain opioid receptors along with other neuropathological changes, which may disturb brain development
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